Patents by Inventor Paul S. Yu

Paul S. Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for treating pulmonary hypertension with a ligand binding domain of a TGF-beta type II receptor
    Patent number: 11951156
    Abstract: In some aspects, the invention teaches pharmaceutical compositions that include a TGF-? ligand trap, and methods of using a TGF-? ligand trap to treat, prevent, or reduce the progression rate of pulmonary hypertension (PH). The invention also provides methods of using a TGF-? ligand trap to treat, prevent, or reduce the progression rate of a variety of conditions including, but not limited to, pulmonary vascular remodeling, pulmonary fibrosis, right ventricular hypertrophy, diseases associated with excessive TGF-? signaling, diseases associated with excessive GDF15 signaling, and diseases associated with excessive PAI-1 signaling. The invention further provides methods of using a TGF-? ligand trap to reduce right ventricular systolic pressure in a subject.
    Type: Grant
    Filed: April 17, 2020
    Date of Patent: April 9, 2024
    Assignees: THE BRIGHAM AND WOMEN'S HOSPITAL, INC., ACCELERON PHARMA, INC.
    Inventors: Paul B. Yu, Asya Grinberg, Dianne S. Sako, Roselyne Castonguay, Rita Steeves, Ravindra Kumar
  • Systems, apparatuses, methods and computer-readable medium for automatically generating playlists based on taste profiles
    Patent number: 10872110
    Abstract: Methods, systems and computer program products for periodically generating a personalized playlist of media objects based on a most recent taste profile of a user. An N-dimensional latent factor vector that defines a taste profile of a user is constructed and matched to an M-dimensional latent factor vector that defines attributes of a media object. A playlist including the first media object is generated based on the matching.
    Type: Grant
    Filed: July 18, 2016
    Date of Patent: December 22, 2020
    Assignee: SPOTIFY AB
    Inventors: Matthew S. Ogle, Christopher Johnson, Edward J. Newett, Paul S. Yu
  • SYSTEMS, APPARATUSES, METHODS AND COMPUTER-READABLE MEDIUM FOR AUTOMATICALLY GENERATING PLAYLISTS BASED ON TASTE PROFILES
    Publication number: 20160335266
    Abstract: Methods, systems and computer program products for periodically generating a personalized playlist of media objects based on a most recent taste profile of a user. A first media object is selected from a media content play history of a first user. A first playlist containing the first media object is identified. A second media object that is not in the media content play history is extracted from the first playlist and a second playlist including the second media object is generated.
    Type: Application
    Filed: July 18, 2016
    Publication date: November 17, 2016
    Inventors: Matthew S. Ogle, Christopher Johnson, Edward J. Newett, Paul S. Yu
  • SYSTEMS, APPARATUSES, METHODS AND COMPUTER-READABLE MEDIUM FOR AUTOMATICALLY GENERATING PLAYLISTS BASED ON TASTE PROFILES
    Publication number: 20160328409
    Abstract: Methods, systems and computer program products for periodically generating a personalized playlist of media objects based on a most recent taste profile of a user. An N-dimensional latent factor vector that defines a taste profile of a user is constructed and matched to an M-dimensional latent factor vector that defines attributes of a media object. A playlist including the first media object is generated based on the matching.
    Type: Application
    Filed: July 18, 2016
    Publication date: November 10, 2016
    Inventors: Matthew S. Ogle, Christopher Johnson, Edward J. Newett, Paul S. Yu
  • Media player display screen with graphical user interface
    Patent number: D930031
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: September 7, 2021
    Assignee: Spotify AB
    Inventors: Thomas Gayno, Jeffrey Paul Baxter, Paul S. Yu, Mark Kizelshteyn
  • Media player display screen with graphical user interface
    Patent number: D979599
    Type: Grant
    Filed: August 3, 2021
    Date of Patent: February 28, 2023
    Assignee: Spotify AB
    Inventors: Thomas Gayno, Jeffrey Paul Baxter, Paul S. Yu, Mark Kizelshteyn