Patents by Inventor Paul Sammak

Paul Sammak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for determining the organization of a cellular component of interest
    Patent number: 8050868
    Abstract: The present invention provides automated methods and associated software for determining the organization of a component of interest in individual cells by determining the amount or distribution of the cellular component of interest as a function of position relative to a reference component in the individual cells.
    Type: Grant
    Filed: March 25, 2002
    Date of Patent: November 1, 2011
    Assignee: Cellomics, Inc.
    Inventors: Gustavo Rosania, Paul Sammak, Richard Rubin
  • METHODS AND SYSTEMS FOR IMAGING CELLS
    Publication number: 20100260406
    Abstract: The invention generally provides methods and systems for determining characteristics of cellular structures. The methods include non-invasive, non-perturbing, automatable, and quantitative methods and may be applied to the examination of cells such as stem cells, embryos, and egg cells.
    Type: Application
    Filed: April 19, 2010
    Publication date: October 14, 2010
    Inventors: Paul Sammak, Rami Mangoubi, Mukund Desai, Christopher Jeffreys
  • Methods and systems for imaging cells
    Patent number: 7711174
    Abstract: The invention generally provides methods and systems for determining characteristics of cellular structures. The methods include non-invasive, non-perturbing, automatable, and quantitative methods and may be applied to the examination of cells such as stem cells, embryos, and egg cells.
    Type: Grant
    Filed: May 13, 2005
    Date of Patent: May 4, 2010
    Assignees: The Charles Stark Draper Laboratory, Inc., University of Pittsburgh of the Commonwealth System of Higher Education
    Inventors: Paul Sammak, Rami Mangoubi, Mukund Desai, Christopher Jeffreys
  • Microbead-based test methods for fluorescence imaging systems
    Patent number: 7482167
    Abstract: The present invention provides a test plate and methods for adjusting fluorescence imaging systems involving using a plate with fluorescent microbeads bound to a surface.
    Type: Grant
    Filed: March 11, 2005
    Date of Patent: January 27, 2009
    Assignee: Cellomics, Inc.
    Inventors: Paul Sammak, Gustavo Rosania, Lawrence J. Zana, Kim Ippolito, Jason Bush, Alex Friedman, Sarah Burroughs Tencza, Ravi Kapur
  • Transplantable cell growth niche and related compositions and methods
    Publication number: 20070077649
    Abstract: Provided is a method of culturing a successor cell from a precursor cell comprising co-culturing a precursor cell such as, without limitation, a human embryonic stem cell or a neuronal stem cell with an adult mesenchymal stem cell. In one embodiment, the adult mesenchymal stem cell is derived from adipose tissue. Also provided is a composition comprising mesenchymal stem cells in a growth matrix biologically-compatible with the cells. In another embodiment, a method of regenerating tissue is provided comprising introducing into a patient a cell growth niche comprising either or both of mesenchymal stem cells and neuronal stem cell or successor cell in a growth matrix biologically-compatible with the cells. In another embodiment, a method of regenerating tissue is provided comprising introducing into a patient a cell growth niche comprising matrix, cells and slow release polymer beads containing growth factors.
    Type: Application
    Filed: September 6, 2006
    Publication date: April 5, 2007
    Inventors: Paul Sammak, Lauren Kokai, Kacey Marra
  • Methods and systems for imaging cells
    Publication number: 20060039593
    Abstract: The invention generally provides methods and systems for determining characteristics of cellular structures. The methods include non-invasive, non-perturbing, automatable, and quantitative methods and may be applied to the examination of cells such as stem cells, embryos, and egg cells.
    Type: Application
    Filed: May 13, 2005
    Publication date: February 23, 2006
    Inventors: Paul Sammak, Rami Mangoubi, Mukund Desai, Christopher Jeffreys
  • Microbead-based test plates and test methods for fluorescence imaging systems
    Publication number: 20050176056
    Abstract: The present invention provides a test plate and methods for adjusting fluorescence imaging systems involving using a plate with fluorescent microbeads bound to a surface.
    Type: Application
    Filed: March 11, 2005
    Publication date: August 11, 2005
    Inventors: Paul Sammak, Gustavo Rosania, Lawrence Zana, Kim Ippolito, Jason Bush, Alex Friedman, Sarah Burroughs Tencza, Ravi Kapur
  • Automated assay for identification of individual cells during kinetic assays
    Patent number: 6917884
    Abstract: The present invention provides methods and software for tracking individual cells during a kinetic cell screening assay.
    Type: Grant
    Filed: December 21, 2001
    Date of Patent: July 12, 2005
    Inventors: Paul Sammak, Gustavo Rosania, Richard Rubin, Michel Nederlof, Oleg P. Lapets, Randall O. Shopoff, Murugan Kannan
  • Microbead-based test plates and test methods for fluorescence imaging systems
    Patent number: 6905881
    Abstract: The present invention provides a test plate and methods for adjusting fluorescence imaging systems involving using a plate with fluorescent microbeads bound to a surface.
    Type: Grant
    Filed: November 30, 2001
    Date of Patent: June 14, 2005
    Inventors: Paul Sammak, Gustavo Rosania, Lawrence J. Zana, Kim Ippolito, Jason Bush, Alex Friedman, Sarah Burroughs Tencza, Ravi Kapur
  • System for cell-based screening
    Patent number: 6716588
    Abstract: The present invention provides automated systems, methods, screens, and software for the analysis of cell spreading. The invention involves providing cells containing fluorescent reporter molecules in an array of locations, contacting the cells with a test stimulus, acquiring images from the cells, and automatically calculating one or more morphological features that provide a measure of cell spreading.
    Type: Grant
    Filed: December 8, 2000
    Date of Patent: April 6, 2004
    Assignee: Cellomics, Inc.
    Inventors: Paul Sammak, Thomas D. Duensing, Richard A. Rubin
  • Methods for determining the organization of a cellular component of interest
    Publication number: 20030059093
    Abstract: The present invention provides automated methods and associated software for determining the organization of a component of interest in individual cells by determining the amount or distribution of the cellular component of interest as a function of position relative to a reference component in the individual cells.
    Type: Application
    Filed: March 25, 2002
    Publication date: March 27, 2003
    Applicant: Cellomics, Inc.
    Inventors: Gustavo Rosania, Paul Sammak, Richard Rubin
  • Automated assay for identification of individual cells during kinetic assays
    Publication number: 20030036853
    Abstract: The present invention provides methods and software for tracking individual cells during a kinetic cell screening assay.
    Type: Application
    Filed: December 21, 2001
    Publication date: February 20, 2003
    Applicant: Cellomics, Inc.
    Inventors: Paul Sammak, Gustavo Rosania, Richard Rubin, Michel Nederlof, Oleg P. Lapets, Randall O. Shopoff, Murugan Kannan
  • Microbead-based test plates and test methods for fluorescence imaging systems
    Publication number: 20020098588
    Abstract: The present invention provides a test plate and methods for adjusting fluorescence imaging systems involving using a plate with fluorescent microbeads bound to a surface.
    Type: Application
    Filed: November 30, 2001
    Publication date: July 25, 2002
    Inventors: Paul Sammak, Gustavo Rosania, Lawrence J. Zana, Kim Ippolito, Jason Bush, Alex Friedman, Sarah Burroughs Tencza, Ravi Kapur
  • System for cell-based screening
    Publication number: 20010041347
    Abstract: The present invention provides automated systems, methods, screens, and software for the analysis of cell spreading. The invention involves providing cells containing fluorescent reporter molecules in an array of locations, contacting the cells with a test stimulus, acquiring images from the cells, and automatically calculating one or more morphological features that provide a measure of cell spreading.
    Type: Application
    Filed: December 8, 2000
    Publication date: November 15, 2001
    Inventors: Paul Sammak, Thomas D. Duensing, Richard A. Rubin