Abstract: A rock rail assembly for a vehicle includes a mounting structure, an arm mounted to the mounting structure, a motor bracket coupled to the mounting structure, a motor mounted to the motor bracket, a pivot bar pivotably coupled with the mounting structure, a rail coupled with the pivot bar and operable to move between stowed and deployed positions, and a sector gear coupled to the pivot bar. The motor has a shaft that includes a first end, a second end, and a worm gear portion. Operation of the motor drives rotation of the shaft. The sector gear is operably engaged with the worm gear portion of the shaft, such that rotation of the shaft by the motor drives pivotal movement of the pivot bar relative to the mounting structure, causing movement of the rail coupled thereto between the stowed and deployed positions.

Abstract: A rock rail assembly for a vehicle includes a mounting assembly coupled to the vehicle and comprising a shock absorption pad, and a rail assembly pivotably coupled to the mounting assembly and having a rail. The shock absorption pad is the vehicle-laterally-outboardmost portion of the mounting assembly. The rail assembly is operable to pivot relative to the mounting assembly to move the rail between a stowed position and a deployed position. In the stowed position of the rail, a portion of the rail abuts the shock absorption pad.

Abstract: A tire rolling resistance estimation system estimates a real-time rolling resistance coefficient of a tire, and includes a tire sensor unit that measures a tire inflation pressure and a tire temperature. A processor is in electronic communication with the tire sensor unit. A steady state coefficient determination module in communication with the processor determines a steady state rolling resistance coefficient of the tire. A steady state tire temperature module in communication with the processor receives the steady state rolling resistance coefficient of the tire and estimates a steady state tire temperature of the tire. A real-time rolling resistance coefficient module in communication with the processor receives the steady state tire temperature of the tire and estimates a real-time rolling resistance coefficient of the tire from the steady state rolling resistance coefficient and a difference between the steady state tire temperature and a current tire temperature from the tire sensor unit.

Abstract: Estimating soot comprises connecting exhaust pipe to engine, exhaust pipe has diesel oxidation catalyst and diesel particulate filter. Fuel injector is connected to exhaust pipe upstream from diesel oxidation catalyst and diesel particulate filter. Delta exhaust pressure sensor measures difference in exhaust pressure at inlet and outlet to diesel particulate filter. Controller is connected to fuel injector and to delta exhaust pressure sensor. Controller determines when to conduct active regeneration of diesel particulate filter based on estimated amount of soot accumulated therein. Controller, in first regeneration mode, causes fuel injector to inject fuel at first rate into exhaust stream, and re-evaluates soot accumulated within diesel particulate filter under increased volumetric flow of exhaust stream. Controller, in second regeneration mode, causes fuel injector to inject fuel at second rate, larger than first rate, into exhaust stream to combust soot trapped in diesel particulate filter.

Abstract: Provided herein are bioengineered immunomodulatory fusion proteins and uses thereof for modulating immune responses, as well as uses for improving a response of a subject to a vaccine, or uses for treating a disease or disorder, such as cancer or a pathogen infection. Provided herein is a single chain trimeric CD40L Fc fusion protein comprising (a) three CD40 ligand CD40L subunits covalently linked to one another by peptide linkers (CD40L trimer); and (b) an Fc monomer peptide.

Abstract: The present disclosure generally relates to auditory nerve stimulation to create the perception of sound in the brain of a subject such as an animal or human being. In one form, a system includes an implantable electrode array including a plurality of spaced apart micro-needles. The system also includes a first electrical lead electrically coupled to and extending from the implantable electrode array, and an auditory signal device configured to produce one or more electrical signals representative of communications received from an external processor. An interposer is configured to electrically couple the implantable electrode array and the auditory signal device in an arrangement where one or more electrical signals produced by the auditory signal device may be transmitted through the first electrical lead to the implantable electrode array. Various novel stimulation strategies can be employed, such as place modulated stimulation signals.

Abstract: The present invention relates to a solid pharmaceutical preparation comprising ?-lipoic acid, dicalcium phosphate and a binder. The solid pharmaceutical preparation has an improved stability and thereby improved bioavailability.

Abstract: Disclosed herein are an exemplary apparatus, system, and methods (e.g., Tactical Passive RFID transponder gloves with Morphological Actuation) comprising a glove made predominately of a resistive fabric that varies resistance per degree of deformation; comprising near field communication RFID tag readers, and a controller coupled to the glove to evaluate the varied resistance. A method of classifying RFID tags is also disclosed.

Abstract: A protein language natural language processing (NLP) system is trained to predict specific biophysiochemical properties. Amino acids of proteins are tokenized and masked. A first neural network is trained on a library of amino acid sequences in an unsupervised or self-supervised manner. The information obtained from the first phase of training is applied in a subsequent training operation via transfer learning, to a second neural network. In aspects, an annotated compact dataset is used to fine-tune the second neural network in a second phase of training, and in a supervised manner, to predict biophysiochemical properties of proteins, including TCR-epitope binding.

Abstract: A method of assembling a vehicle component, a system for assembling a vehicle component, and a vehicle component assembly. A blank is formed from a steel sheet, wherein the steel sheet includes a coating on a surface. The coating is removed from a first interface surface of the blank and the blank is stamped either prior to or after removing the coating. The first dynamic interface surface is arranged relative to a second interface surface and thermally joined to form a joint.

Abstract: A clipping system includes an adapter configured to be mounted over an insertion device and a clip including first and second jaws movable between an insertion configuration and an initial deployed configuration. A first extending member is releasably coupled to the clip and movably connected to the adapter to permit a movement of the clip relative to the adapter from the insertion configuration to the initial deployed configuration. The first extending member is configured to permit withdrawal of the adapter away from the clip to place the system in a review configuration to enhance a visual observation of the clip. The first extending member is operable to retract the clip over the adapter so that the clip is forced open, freeing the clip from tissue on which it has been clipped. The first extending member is configured to release the clip therefrom in a final deployed configuration.

Abstract: Disclosed herein are virus-like particle (VLP)-based bivalent vaccine compositions. The compositions may comprise a spherical retroviral Group-specific Antigen (“Gag”) protein core and at least two Ebola glycoproteins. The at least two Ebola glycoproteins may be located at the exterior surface of the spherical Gag protein core, such that the VLP-based vaccine presents at least two Ebola glycoprotein antigens. In one aspect, the at least two Ebola glycoproteins are a Zaire (EBOV) glycoprotein, and a Sudan (SUDV) glycoprotein.

Abstract: A medical device, comprising a handle, wherein the handle includes a movable body and a stationary body; an end cap, the end cap comprising an inner cap and an outer cap, wherein the inner cap is coupled to the movable body by a control element such that movement of the movable body relative to the stationary body extends the inner cap relative to the outer cap; and a patch disposed between the inner cap and the outer cap such that movement of the inner cap relative to the outer cap at least partially deploys the patch.

Abstract: Examples are disclosed that relate to generating expressive avatars using multi-modal three-dimensional face modeling and tracking. One example includes a computer system comprising a processor coupled to a storage system that stores instructions. Upon execution by the processor, the instructions cause the processor to receive initialization data describing an initial state of a facial model. The instructions further cause the processor to receive a plurality of multi-modal data signals. The instructions further cause the processor to perform a fitting process using the initialization data and the plurality of multi-modal data signals. The instructions further cause the processor to determine a set of parameters based on the fitting process, wherein the determined set of parameters describes an updated state of the facial model.

Abstract: An integrated circuit (IC), including: a set of cascaded clock gating control (CGC) circuits, wherein a first one of the set of cascaded CGC circuits includes a clock input configured to receive a clock signal; an observation flip-flop including a clock input coupled to a clock output of a last one of the set of cascaded CGC circuits; an input register configured to provide logic zeros (0s) to clock enable (CE) inputs of the set of cascaded CGC circuits pursuant to a stuck-at-one (SA1) fault testing on the CE input of a selected one of the set of cascaded CGC circuits; and a set of one or more test enable (TE) control registers configured to provide one or more logic ones (1s) to one or more TE inputs of one or more of the set of cascaded CGC circuits not undergoing the stuck-at-one (SA1) fault testing, respectively.

Abstract: A humidification system can include a heater base, a humidification chamber, and a breathing circuit. A cartridge can be removably coupled to the heater base. The cartridge can include various sensors, probes, sensor wire connectors, heater wire connectors, and/or other features. The cartridge can include features configured to mate with corresponding features on the humidification chamber and the heater base. The cartridge includes a memory, such as an EEPROM, or other suitable storage device. When the cartridge is installed on the heater base, the memory is electrically connected to a processor and/or memory of the heater base. Various models of cartridges can be produced for use with different humidification chambers, breathing circuits, and/or therapies. A connector can be configured to couple an inspiratory conduit to an outlet port of the humidification chamber. The connector can provide a pneumatic connection to the outlet port and an electrical connection to the cartridge.

Abstract: A drive mode hierarchy includes drive mode categories and drive modes belonging to each category. Each drive mode defines values for attributes of the drivetrain and/or suspension of a vehicle. Each drive mode may further have towing and non-towing sub-modes with the towing sub-mode being used when a trailer is detected. An interface is provided for selecting drive modes from the hierarchy and modifying the attributes. The vehicle may define a plurality of trailer profiles including attributes of trailers, such as weight and aerodynamic drag. A user may select among trailer profiles and define the attributes of the trailer profiles. Interfaces displayed by the vehicle may vary according to the selected drive mode and may include a chassis view with interface elements displaying real-time information of components of the vehicle, such as wheels, suspension, and battery. Tiles including real-time information may be displayed according to the selected drive mode.

Abstract: Described herein are examples of a computerized method that comprises: in response to obtaining information regarding a potential collision between a vehicle and an object, obtaining data describing the vehicle for a time period extending before and after a time of the potential collision. The method may determine a likelihood that the potential collision is a non-collision event based on the data describing the vehicle by performing one or more assessments. The assessments may include telematics monitor assessment, driver behavior assessment, road surface feature assessment, trip correlation assessment, and/or context assessment. In response to determining that the likelihood indicates that the potential collision is not a non-collision event, the method may trigger one or more actions responding to the potential collision.

Abstract: The embodiments herein provide a method and system for an augmented reality based indoor navigation. The system creates an augmented reality (AR) based fingerprinting to perform the dynamic routing. A floor wise plan of the building is uploaded. The floor plan is converted to a floor plan graph. Then cloud anchors are created and placed across the floor. An anchor is a fixed position and orientation in the real world as recognized by any Augmented Reality (AR) device. Each time an anchor is placed, its position information is fingerprinted on the floorplan graph and that fingerprinting is saved in the database. When user scans for nearest QR code to identify their current position, the user location is identified and the planogram details, fingerprinting and pre-processed floorplan matrix are obtained from database. When user selects his destination, dynamic routing is performed to obtain shortest/optimized path viewed through augmented reality fingerprinting.

Abstract: A system for increasing joint strength and reducing embrittlement in a resistance spot weld of metal workpieces is disclosed. The system comprises a stackup of first and second metal workpieces, and an interface member disposed between the first and second metal workpieces. The interface member comprises a peripheral wall defining a hollow inner portion. The peripheral wall has a first open end extending to a second open end. The first open end is in contact with the first metal workpiece defining a first weld portion thereon. The second open end is in contact with the second metal workpiece defining a second weld portion thereon. The system further comprises a first electrode configured to contact the first metal workpiece to heat the peripheral wall at the first weld portion and join the first metal workpiece with the first open end of the peripheral wall.