Abstract: A hydraulic system for controlling bleed down and retraction of a boom within a safety envelope includes a backup battery power supply, and at least a first boom lift hydraulic cylinder configured to raise and lower the boom. The first boom lift hydraulic cylinder includes a solenoid bleed valve electrically connected to the backup battery power supply. The hydraulic system also includes an input device controllable by an operator of the boom. The input device may, for instance, be used by the operator to initiate bleed down and retraction of the boom from an elevated position. To accommodate independent failsafe features of the system, the input device is configured to selectively actuate the solenoid bleed valve using electrical power supplied from the backup battery power supply.

Abstract: Catheter-based devices and associated methods for immune system neuromodulation of human patients are disclosed herein. One aspect of the present technology is directed to methods of treating a human patient diagnosed with an immune system condition. The methods can include intravascularly positioning a neuromodulation catheter within a blood vessel proximate to neural fibers innervating an immune system organ of the patient. The method also includes reducing sympathetic neural activity in the patient by delivering energy to the neural fibers innervating the immune system organ via the neuromodulation catheter. Reducing sympathetic neural activity improves a measurable physiological parameter corresponding to the immune system condition of the patient.

Abstract: Catheter-based devices and associated methods for immune system neuromodulation of human patients are disclosed herein. One aspect of the present technology is directed to methods of treating a human patient diagnosed with an immune system condition. The methods can include intravascularly positioning a neuromodulation catheter within a blood vessel proximate to neural fibers innervating an immune system organ of the patient. The method also includes reducing sympathetic neural activity in the patient by delivering energy to the neural fibers innervating the immune system organ via the neuromodulation catheter. Reducing sympathetic neural activity improves a measurable physiological parameter corresponding to the immune system condition of the patient.

Abstract: A method of operating a construction machine that includes a base, support arms each pivotally coupled to the base, and a plurality of wheel assemblies each coupled to the one of the support arms, the method including, in a transport mode of the construction machine, turning a wheel of each of the wheel assemblies, independently from a wheel of another of the wheel assemblies, to a toe out orientation. The method also includes driving each support arm to a deployed condition of the support arm in an operational mode of the construction machine. Driving each support arm to the deployed condition causes the distal ends of each of the support arms to move away from one another and outwardly from the base. The method also includes locking each support arm in the deployed condition and controlling steering of each wheel in the operational mode of the construction machine.

Abstract: A support system for a vehicle includes a base and at least a first and a second support arm. Each of the first and the second support arms include a base end pivotally coupled to the base through a respective hinge assembly. Each of the first and the second support arms further include a distal end opposite the base end. The support system also includes a respective wheel assembly coupled to each distal end. Each wheel assembly includes an independently powered and steerable wheel configured to engage a travel surface, a propelling motor configured to drive a respective first support arm between a stowed condition and a deployed condition unaided while the vehicle remains stationary, and a steer actuator configured to change an angle of the wheel with respect to a respective support arm.

Abstract: A catheter-based device for determining the radial expansion force required to displace an occlusion in a vessel located in a subject. The device comprises an elongate body defining proximal and distal termini. The body comprises a sheath that encloses a hollow lumen within, which extends along substantially the full length of the body. The proximal terminal region of the body comprises: a user-interfacing hub, the hub comprising a handle for maneuvering the body and configured for handling by an operator; a control interface for controlling the device; and a sensor configured to measure one or more parameters relevant to a force applied to the vessel by the device. The distal terminal region of the body comprises an expandable member movable between a retracted position, in which the expandable member is within the hollow lumen, and a deployed position, in which the expandable member is disposed beyond the distal terminus, and controllable via the control interface to expand radially.

Abstract: A stent system is provided comprising a primary stent for location in a lumen of a target vessel, such as a vein or artery that may be fully or partially occluded. The primary stent contacts a vessel wall and at least one secondary stent element is deployed wholly within the primary stent and configured to engage with the interior surface of the primary stent. The secondary stent element is configured to apply a chronic outward radial force to the interior surface of the primary stent so as to effect modification of or to resist change to an aspect ratio of the lumen of the target vessel at the location where the secondary stent element is deployed. In this way the secondary stent element cooperates with the primary stent to restore patency to the target vessel. Various configurations of the stent system are provided as well as deployment devices and methods of treating fully or partially occluded vessels.

Abstract: Systems and methods include differential diagnosis for acute heart failure to provide treatment to a patient including determining whether the patient has cardiac volume overload, determining whether the patient has decreased abdominal venous system volume, and providing the appropriate treatment in response to the determinations. A multi-sensor system may be used to determine cardiac volume and abdominal venous system volume. Fluid redistribution treatment may be provided when cardiac volume overload is accompanied by a decrease in abdominal venous system volume. Fluid accumulation treatment may be provided when cardiac volume overload is not accompanied by a decrease in abdominal venous system volume.

Abstract: Methods for treating dyspnea with therapeutic renal neuromodulation and associated system and methods are disclosed herein. One aspect of the present technology, for example, is directed to methods that block, reduce, and/or inhibit renal sympathetic nerve activity to achieve a reduction in central sympathetic tone. Renal sympathetic nerve activity may be altered or modulated along the afferent and/or efferent pathway. The achieved reduction in central sympathetic tone may carry therapeutic benefits for patients with dyspnea.

Abstract: A hydraulic system for controlling bleed down and retraction of a boom within a safety envelope includes a backup battery power supply, and at least a first boom lift hydraulic cylinder configured to raise and lower the boom. The first boom lift hydraulic cylinder includes a solenoid bleed valve electrically connected to the backup battery power supply. The hydraulic system also includes an input device controllable by an operator of the boom. The input device may, for instance, be used by the operator to initiate bleed down and retraction of the boom from an elevated position. To accommodate independent failsafe features of the system, the input device is configured to selectively actuate the solenoid bleed valve using electrical power supplied from the backup battery power supply.

Abstract: Aspects of the invention provide a self-expanding stent device. The device comprises: an elongated body that defines a lumen within. The body has a first and a second terminus and a longitudinal axis located therebetween. The body comprises a first zone and a second zone along the longitudinal axis. When the device is in an expanded configuration the first zone has a first radial strength that is resistant to an external compressive force, and the second zone has a second radial strength that is resistant to an external compressive force. The radial strength of the first zone is greater than that of the second zone. The diameter of the body lumen proximal to the first terminus is greater than that of the lumen proximal to the second terminus.

Abstract: Methods for treating polycystic kidney disease with therapeutic renal neuromodulation and associated systems and methods are disclosed herein. One aspect of the present technology is directed to methods that at least partially inhibit sympathetic neural activity in nerves proximate a renal artery of a kidney of a patient. One or more measurable physiological parameter corresponding to the polycystic kidney disease can thereby be reduced. Moreover, central sympathetic drive in the patient can be reduced in a manner that treats the patient for the polycystic kidney disease. Renal sympathetic nerve activity can be modulated along the afferent and/or efferent pathway. The modulation can be achieved, for example, using an intravascularly positioned catheter carrying a neuromodulation assembly, e.g., a neuromodulation assembly configured to cryotherapeutically cool the renal nerve or to deliver an energy field to the renal nerve.

Abstract: An aerial work vehicle (AWV) includes a boom, and a work platform coupled to a distal end of the boom, where the work platform has a forward end in a direction of travel and an aft end opposite the forward end. The AWV also includes a first control device mechanically coupled to one of the forward end of the work platform or the aft end of the work platform and configured to control operation of at least the boom. In addition, the AWV includes an alternate, second, control device configured to control operation of at least the boom, which may be at least one of wireless and/or mechanically coupled to the work platform at a location different from a location of the first control device.

Abstract: A support system for a vehicle includes a base and at least a first and a second support arm. Each of the first and the second support arms include a base end pivotally coupled to the base through a respective hinge assembly. Each of the first and the second support arms further include a distal end opposite the base end. The support system also includes a respective wheel assembly coupled to each distal end. Each wheel assembly includes an independently powered and steerable wheel configured to engage a travel surface, a propelling motor configured to drive a respective first support arm between a stowed condition and a deployed condition unaided while the vehicle remains stationary, and a steer actuator configured to change an angle of the wheel with respect to a respective support arm.

Abstract: Catheter-based devices and associated methods for immune system neuromodulation of human patients are disclosed herein. One aspect of the present technology is directed to methods of treating a human patient diagnosed with an immune system condition. The methods can include intravascularly positioning a neuromodulation catheter within a blood vessel proximate to neural fibers innervating an immune system organ of the patient. The method also includes reducing sympathetic neural activity in the patient by delivering energy to the neural fibers innervating the immune system organ via the neuromodulation catheter. Reducing sympathetic neural activity improves a measurable physiological parameter corresponding to the immune system condition of the patient.

Abstract: Methods for treating polycystic ovary syndrome with therapeutic ovarian neuromodulation and associated systems and methods are disclosed herein. Polycystic ovary syndrome can be associated, for example, with a condition including at least one of oligo/amenorrhea, infertility, hirsutism, obesity, metabolic syndrome, insulin resistance, and increased cardiovascular risk profile. One aspect of the present technology is directed to methods that at least partially inhibit sympathetic neural activity in nerves proximate an ovarian artery of an ovary of a patient. Sympathetic drive in the patient can thereby be reduced in a manner that treats the patient for the polycystic ovary syndrome. Ovarian sympathetic nerve activity can be modulated along afferent and/or efferent pathways. The modulation can be achieved, for example, using an intravascularly positioned catheter carrying a therapeutic assembly, e.g.

Abstract: Systems and methods include differential diagnosis for acute heart failure to provide treatment to a patient including determining whether the patient has cardiac volume overload, determining whether the patient has decreased abdominal venous system volume, and providing the appropriate treatment in response to the determinations. A multi-sensor system may be used to determine cardiac volume and abdominal venous system volume. Fluid redistribution treatment may be provided when cardiac volume overload is accompanied by a decrease in abdominal venous system volume. Fluid accumulation treatment may be provided when cardiac volume overload is not accompanied by a decrease in abdominal venous system volume.

Abstract: Methods for treating dyspnea with therapeutic renal neuromodulation and associated system and methods are disclosed herein. One aspect of the present technology, for example, is directed to methods that block, reduce, and/or inhibit renal sympathetic nerve activity to achieve a reduction in central sympathetic tone. Renal sympathetic nerve activity may be altered or modulated along the afferent and/or efferent pathway. The achieved reduction in central sympathetic tone may carry therapeutic benefits for patients with dyspnea.

Abstract: Methods for treating dyspnea with therapeutic renal neuromodulation and associated system and methods are disclosed herein. One aspect of the present technology, for example, is directed to methods that block, reduce, and/or inhibit renal sympathetic nerve activity to achieve a reduction in central sympathetic tone. Renal sympathetic nerve activity may be altered or modulated along the afferent and/or efferent pathway. The achieved reduction in central sympathetic tone may carry therapeutic benefits for patients with dyspnea.

Abstract: Methods for therapeutic renal denervation are disclosed herein. One aspect of the present application, for example, is directed to methods that block, reduce and/or inhibit renal sympathetic nerve activity to achieve a reduction in central sympathetic tone. Renal sympathetic nerve activity may be altered or modulated along the afferent and/or efferent pathway. The achieved reduction in central sympathetic tone may carry several therapeutic benefits across many disease states.