Abstract: A bladder fullness monitoring system includes a controller and an active optical sensor that is affixed to a patient's bladder. The sensor emits light onto the bladder and further detects light reflected from the bladder, in order to generate an output signal that indicates an amount of emitted light was reflected back to the detector. The controller is coupled to the optical sensor to receive and interpret the output signals, e.g., to determine when the bladder is full. The controller may be operatively coupled to a urinary control apparatus which uses the output signals to trigger urination in patients who have lost the ability to voluntarily urinate. Embodiments are particularly useful for monitoring bladder fullness in patients who have lost bladder sensation and/or the ability to voluntary urinate and rely on a urinary control apparatus in order to urinate.

Abstract: A bladder fullness monitoring systems includes a controller and an active optical sensor that is affixed to a patient's bladder. The sensor emits light onto the bladder and further detects light reflected from the bladder, in order to generate an output signal that indicates an amount of emitted light was reflected back to the detector. The controller is coupled to the optical sensor to receive and interpret the output signals, e.g., to determine when the bladder is full. The controller may be operatively coupled to a urinary control apparatus which uses the output signals to trigger urination in patients who have lost the ability to voluntarily urinate. Embodiments are particularly useful for monitoring bladder fullness in patients who have lost bladder sensation and/or the ability to voluntary urinate and rely on a urinary control apparatus in order to urinate.

Abstract: A header lock assembly includes a header lock pin and mating lead lock collar that provide a releasable coupling for attaching one or more leads to a device. The header lock assembly is configured to engage the lead to assure closure while not applying undue pressure on the lead. One or more notches in the header lock pin allow the lead to pass the header lock pin unimpeded while the header lock assembly is in an unlocked configuration. Rotation of the header lock pin engages a circumferential groove in the lead lock collar to secure the lead to the header. A slot in the top of the header lock pin provides an interface surface with a lead locking tool for rotating the header lock pin. The slot orientation provides a visual indication of the header lock assembly being in a locked or unlocked configuration.

Abstract: The devices, systems, and methods include a catheter including a flexible tube having a proximal end and a distal end, the catheter defining a lumen extending from the proximal end to the distal end. The tube defines a plurality of slits. The distal end of the tube includes an atraumatic tip configured to be advanced through an opening in a skull to a target treatment site within the brain. A detachable connector is attached to the proximal end of the tube. Upon delivery of a fluid to the catheter from an external fluid source, the slits in the tube are responsive to pressure of the fluid within the catheter, by the slits opening to disperse the fluid from the lumen of the tube. The slits are responsive to a drop in pressure of the fluid within the catheter, by the slits closing.

Abstract: A cuff is described for a target anatomic feature within a body, along with a system for utilizing the cuff. The cuff includes a band defining a circumferential opening extending along a length of the band; and a pair of engagement surfaces defined by or affixed to the cuff, the engagement surfaces structured for application of a spreading force to be distributed continuously along a portion of the circumferential opening, thereby increasing the circumferential opening and expanding the cuff for a closed configuration to an open configuration sized for placement of the cuff. The cuff is structured to remain in the closed configuration in the absence of the spreading force and automatically return to the closed configuration after removal of the spreading force.

Abstract: A lead device is provided for a medical treatment apparatus, where the lead device includes protruding anchoring mechanisms for anchoring the lead device in tissue. The anchoring mechanism include permanent anchoring mechanisms, or a combination of permanent and dissolvable anchoring mechanisms, to anchor the device in tissue. The anchoring mechanism resists migration of the lead device in at least one or both axial directions.

Abstract: A lead device is provided for a medical treatment apparatus, where the lead device includes mechanisms for anchoring the lead device in tissue.

Abstract: Various embodiments provide an apparatus, system method for treating neurological conditions by delivering solid form medication to the ventricles or other areas of the brain. Particular embodiments provide an apparatus and method for treating epilepsy and other neurological conditions by delivering solid form medication to ventricles in the brain wherein the medication is contained in a diffusion chamber so as to allow the medication to dissolve in the cerebrospinal fluid of the brain and then diffuse out of the diffusion chamber to be delivered to the ventricles and brain tissue. In one or more embodiments, portions of apparatus have sufficient flexibility to conform to the shape of the ventricles of the brain when advanced into them and/or to not cause deformation of the ventricle sufficient to cause a significant physiologic effect.

Abstract: A device for detecting a being left within a vehicle includes a sensor that detects when a being (e.g. a pet, a child, etc.) is within a vehicle and the operator of the vehicle has moved away from the vehicle by more than, for example five feet. Upon detection of such, the device emits a sound to notify others nearby of the being that was left within the vehicle. The sound is preferably different than a sound of a typical vehicle theft alarm system. In a preferred embodiment, determination that the operator has left the vehicle is by a loss of a signal from a personal transmitter that is attached to the operator's key ring or worn by the operator. After moving away from the vehicle by more than five feet, the signal from the personal transmitter decreases and initiates determination if a being remains within the vehicle.

Abstract: Various embodiments provide an apparatus, system method for treating neurological conditions by delivering solid form medication to the ventricles or other areas of the brain. Particular embodiments provide an apparatus and method for treating epilepsy and other neurological conditions by delivering solid form medication to ventricles in the brain wherein the medication is contained in a diffusion chamber so as to allow the medication to dissolve in the cerebrospinal fluid of the brain and then diffuse out of the diffusion chamber to be delivered to the ventricles and brain tissue. In one or more embodiments, portions of apparatus have sufficient flexibility to conform to the shape of the ventricles of the brain when advanced into them and/or to not cause deformation of the ventricle sufficient to cause a significant physiologic effect.

Abstract: A device for detecting a being left within a vehicle includes a sensor that detects when a being (e.g. a pet, a child, etc.) is within a vehicle and the operator of the vehicle has moved away from the vehicle by more than, for example five feet. Upon detection of such, the device emits a sound to notify others nearby of the being that was left within the vehicle. The sound is preferably different than a sound of a typical vehicle theft alarm system. In a preferred embodiment, determination that the operator has left the vehicle is by a loss of a signal from a personal transmitter that is attached to the operator's key ring or worn by the operator. After moving away from the vehicle by more than five feet, the signal from the personal transmitter decreases and initiates determination if a being remains within the vehicle.

Abstract: Various embodiments provide an apparatus, system method for treating neurological conditions by delivering solid form medication to the ventricles or other areas of the brain. Particular embodiments provide an apparatus and method for treating epilepsy and other neurological conditions by delivering solid form medication to ventricles in the brain wherein the medication is contained in a diffusion chamber so as to allow the medication to dissolve in the cerebrospinal fluid of the brain and then diffuse out of the diffusion chamber to be delivered to the ventricles and brain tissue. In one or more embodiments, portions of apparatus have sufficient flexibility to conform to the shape of the ventricles of the brain when advanced into them and/or to not cause deformation of the ventricle sufficient to cause a significant physiologic effect.

Abstract: Embodiments of the invention provide drug packaging and methods for producing drug packaging which can be sealed at room temperature and/or without the need for elevated temperatures above room temperature. Many embodiments provide drug packaging comprising pierceable tubing having a capsule shape (also referred to herein as a pierceable capsule and/or pierceable drug capsule) containing a solid drug such as a drug pellet and methods for producing pierceable drug capsules which can be sealed at room temperature. Embodiments are particularly useful for the packaging and delivery of drugs used in implantable drug delivery devices as well as packaging of drugs that are easily thermally degraded.

Abstract: A device for detecting a being left within a vehicle includes a sensor that detects when a being (e.g. a pet, a child, etc.) is within a vehicle and the operator of the vehicle has moved away from the vehicle by more than, for example five feet. Upon detection of such, the device emits a sound to notify others nearby of the being that was left within the vehicle. The sound is preferably different than a sound of a typical vehicle theft alarm system. In a preferred embodiment, determination that the operator has left the vehicle is by a loss of a signal from a personal transmitter that is attached to the operator's key ring or worn by the operator. After moving away from the vehicle by more than five feet, the signal from the personal transmitter decreases and initiates determination if a being remains within the vehicle.

Abstract: A device for detecting a being left within a vehicle includes a sensor that detects when a being (e.g. a pet, a child, etc.) is within a vehicle and the operator of the vehicle has moved away from the vehicle by more than, for example five feet. Upon detection of such, the device emits a sound to notify others nearby of the being that was left within the vehicle. The sound is preferably different than a sound of a typical vehicle theft alarm system. In a preferred embodiment, determination that the operator has left the vehicle is by a loss of a signal from a personal transmitter that is attached to the operator's key ring or worn by the operator. After moving away from the vehicle by more than five feet, the signal from the personal transmitter decreases and initiates determination if a being remains within the vehicle.

Abstract: Embodiments of the invention provide bladder fullness monitoring systems and associated methods for such monitoring. One includes a controller and an active optical sensor that is affixed to a patient's bladder. The sensor emits light onto the bladder and further detects light reflected from the bladder, in order to generate an output signal that indicates an amount of emitted light was reflected back to the detector. The controller is coupled to the optical sensor to receive and interpret the output signals, e.g., to determine when the bladder is full. The controller may be operatively coupled to a urinary control apparatus which uses the output signals to trigger urination in patients who have lost the ability to voluntarily urinate. Embodiments are particularly useful for monitoring bladder fullness in patients who have lost bladder sensation and/or the ability to voluntary urinate and rely on a urinary control apparatus in order to urinate.

Abstract: Embodiments of the invention provide drug packaging and methods for producing drug packaging which can be sealed at room temperature and/or without the need for elevated temperatures above room temperature. Many embodiments provide drug packaging comprising pierceable tubing having a capsule shape (also referred to herein as a pierceable capsule and/or pierceable drug capsule) containing a solid drug such as a drug pellet and methods for producing pierceable drug capsules which can be sealed at room temperature. Embodiments are particularly useful for the packaging and delivery of drugs used in implantable drug delivery devices as well as packaging of drugs that are easily thermally degraded.

Abstract: Embodiments of the invention provide drug packaging and methods for producing drug packaging which can be sealed at room temperature and/or without the need for elevated temperatures above room temperature. Many embodiments provide drug packaging comprising pierceable tubing having a capsule shape (also referred to herein as a pierceable capsule and/or pierceable drug capsule) containing a solid drug such as a drug pellet and methods for producing pierceable drug capsules which can be sealed at room temperature. Embodiments are particularly useful for the packaging and delivery of drugs used in implantable drug delivery devices as well as packaging of drugs that are easily thermally degraded.

Abstract: Embodiments provide apparatus and methods for delivering solid form medications such as drug cords (DC) to various locations in the body. The DCs may comprise one or more drugs and excipients. One embodiment provides an apparatus for in vivo delivery of DCs comprising a housing including a port, a DC disposed in the housing on a spool or like device and a mechanism for advancing the DCs from the inside the housing to a delivery site (DS) outside the housing. The apparatus can be used to deliver selected lengths of DC corresponding to a dose of drug to treat a medical condition. The DC can be delivered to the DS at regular intervals or responsive to a detected biological event. Embodiments of the invention are particularly useful for delivering medication to treat a selected medical condition over an extended period without requiring a patient to take external medication.

Abstract: Embodiments of the invention provide drug packaging and methods for producing drug packaging which can be sealed at room temperature and/or without the need for elevated temperatures above room temperature. Many embodiments provide drug packaging comprising pierceable tubing having a capsule shape (also referred to herein as a pierceable capsule and/or pierceable drug capsule) containing a solid drug such as a drug pellet and methods for producing pierceable drug capsules which can be sealed at room temperature. Embodiments are particularly useful for the packaging and delivery of drugs used in implantable drug delivery devices as well as packaging of drugs that are easily thermally degraded.