Patents by Inventor Paul T. Englund

Paul T. Englund has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Furyl containing fatty acids, glycosyl phosphatidylinositol (GPI) analogues used for inhibiting parasitic activity
    Patent number: 6048989
    Abstract: A method of inhibiting parasitic activity is disclosed in which the biosynthesis, structure and/or function of the glycosyl phosphatidylinositol (GPI) anchor of said parasite may be affected by incorporating into said GPI anchor selected analogs of myristic acid containing various heteroatoms, substituents and unsaturated bonds, including ester-containing analogs, ketocarbonyl-containing analogs, sulfur-containing analogs, double bond- and triple bond-containing analogs, aromatic moiety-containing analogs, nitrated analogs and halogenated analogs.
    Type: Grant
    Filed: December 15, 1997
    Date of Patent: April 11, 2000
    Assignee: Washington University
    Inventors: Jeffrey I. Gordon, George W. Gokel, Paul T. Englund
  • Method of inhibiting parasitic activity
    Patent number: 6025511
    Abstract: A method of inhibiting parasitic activity is disclosed in which the biosynthesis, structure and/or function of the glycosyl phosphatidylinositol (GPI) anchor of said parasite may be affected by incorporating into said GPI anchor selected analogs of myristic acid containing various heteroatoms, substituents and unsaturated bonds, including ester-containing analogs, ketocarbonyl-containing analogs, sulfur-containing analogs, double bond- and triple bond-containing analogs, aromatic moiety-containing analogs, nitrated analogs and halogenated analogs.
    Type: Grant
    Filed: March 31, 1998
    Date of Patent: February 15, 2000
    Assignees: Washington University, Johns Hopkins University
    Inventors: Jeffrey I. Gordon, George W. Gokel, Paul T. Englund
  • Method of inhibiting parasitic activity
    Patent number: 6001869
    Abstract: A method of inhibiting parasitic activity is disclosed in which the biosynthesis, structure and/or function of the glycosyl phosphatidylinositol (GPI) anchor of said parasite may be affected by incorporating into said GPI anchor selected analogs of myristic acid containing various heteroatoms, substituents and unsaturated bonds, including ester-containing analogs, ketocarbonyl-containing analogs, sulfur-containing analogs, double bond- and triple bond-containing analogs, aromatic moiety-containing analogs, nitrated analogs and halogenated analogs.
    Type: Grant
    Filed: December 15, 1997
    Date of Patent: December 14, 1999
    Assignees: Washington University, Johns Hopkins University
    Inventors: Jeffrey I. Gordon, George W. Gokel, Paul T. Englund
  • Thienyl-containing fatty acid glycosyl phosphatidylinosital analogues used for inhibiting parasitic activity
    Patent number: 5998642
    Abstract: A method of inhibiting parasitic activity is disclosed in which the biosynthesis, structure and/or function of the glycosyl phosphatidylinositol (GPI) anchor of said parasite may be affected by incorporating into said GPI anchor selected analogs of myristic acid containing various heteroatoms, substituents and unsaturated bonds, including ester-containing analogs, ketocarbonyl-containing analogs, sulfur-containing analogs, double bond- and triple bond-containing analogs, aromatic moiety-containing analogs, nitrated analogs and halogenated analogs.
    Type: Grant
    Filed: December 15, 1997
    Date of Patent: December 7, 1999
    Assignee: Washington University
    Inventors: Jeffrey I. Gordon, George W. Gokel, Paul T. Englund
  • Tetradecadienoic acid, a glycosyl phosphatidylinositol (GPI) analogue used for inhibiting parasitic activity
    Patent number: 5760259
    Abstract: A method of inhibiting parasitic activity is disclosed in which the biosynthesis, structure and/or function of the glycotyl phosphatidylinositol (GPI) anchor of said parasite may be affected by incorporating into said GPI anchor selected analogs of myristic acid containing various heteroatoms, substituents and unsaturated bonds, including ester-containing analogs, ketocarbonyl-containing analogs, sulfur-containing analogs, double bond- and triple bond-containing analogs, aromatic moiety-containing analogs, nitrated analogs and halogenated analogs.
    Type: Grant
    Filed: March 18, 1996
    Date of Patent: June 2, 1998
    Assignees: Washington University, Johns Hopkins Univ.
    Inventors: Jeffrey I. Gordon, George W. Gokel, Paul T. Englund
  • Method of inhibiting parasitic activity
    Patent number: 5747537
    Abstract: A method of inhibiting parasitic activity is disclosed in which the biosynthesis, structure and/or function of the glycosyl phosphatidylinositol (GPI) anchor of said parasite may be affected by incorporating into said GPI anchor selected analogs of myristic acid containing various heteroatoms, substituents and unsaturated bonds, including ester-containing analogs, ketocarbonyl-containing analogs, sulfur-containing analogs, double bond- and triple bond-containing analogs, aromatic moiety-containing analogs, nitrated analogs and halogenated analogs.
    Type: Grant
    Filed: September 5, 1995
    Date of Patent: May 5, 1998
    Assignees: Washington University, Johns Hopkins University
    Inventors: Jeffrey I. Gordon, George W. Gokel, Paul T. Englund