Patents by Inventor Paul Trescony
Paul Trescony has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20120277748Abstract: A plate for connecting a first portion of bone and a second portion of bone is disclosed. The plate comprises a central longitudinal axis, a first end portion extending along the central longitudinal axis and configured to affix to the first portion of bone, a second end portion extending along the central longitudinal axis and configured to affix to the second portion of bone, and an intermediary portion extending along the central longitudinal axis and between the first end portion and the second end portion. The intermediary portion comprises three continuous segments of material, two segments of which extend along a direction substantially parallel to the central longitudinal axis, and one segment of which extends along a direction substantially perpendicular to the central longitudinal axis.Type: ApplicationFiled: April 28, 2011Publication date: November 1, 2012Applicant: Warsaw Orthopedic, Inc.Inventors: Paul Trescony, Jeffrey Rouleau, Matthew Jolly
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Publication number: 20080103352Abstract: In general, the invention is directed to devices and methods that are useful for surface preparation of implantable medical devices. In the case of a vascular graft, the invention presents devices and methods that enhance endothelial cell seeding by providing recesses in the luminal surface that can receive endothelial cells. When the device is constructed of a material such as expanded polytetrafluoroethylene (ePTFE), the recesses may be created by physical processing of the microstructures of the material. The physical processing lifts nodes from the surface, forming recesses that can receive endothelial cells.Type: ApplicationFiled: January 9, 2008Publication date: May 1, 2008Inventors: Nicolas Rivron, Paul Trescony, Michael Wolf
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Publication number: 20070059335Abstract: Apparatus and methods for seeding an implantable medical device, such as a vascular prosthesis, with cells, such as endothelial cells, are described. The invention supports techniques for seeding a luminal surface of the device with axial centrifugation. Cells are introduced in suspension into the lumen of the device. The introduction of the cells may occur after a blood centrifugation product, such as platelet-poor plasma, is applied to the luminal surface. After the cells are introduced, the device is then subjected to centrifugation around a longitudinal axis defined by the lumen. Axial centrifugation causes the cells to concentrate toward and adhere to the luminal surface. Shortly after axial centrifugation, the seeded device can be presented for implantation in a patient. The implantable medical device may be inserted into a protective sleeve prior to seeding the device with cells, and the sleeve may or may not be removed prior to implantation.Type: ApplicationFiled: September 1, 2006Publication date: March 15, 2007Applicant: Medtronic, Inc.Inventors: Michael Wolf, Laurie Yunker, Paul Trescony
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Publication number: 20070048352Abstract: A method for making a medical device having at least one biomolecule immobilized on a substrate surface is provided. One method of the present invention includes immobilizing a biomolecule comprising an unsubstituted amide moiety on a biomaterial surface. Another method of the present invention includes immobilizing a biomolecule on a biomaterial surface comprising an unsubstituted amide moiety. Still another method of the present invention may be employed to crosslink biomolecules comprising unsubstituted amide moieties immobilized on medical device surfaces. Additionally, one method of the present invention may be employed to crosslink biomolecules comprising unsubstituted amide moieties in solution, thereby forming a crosslinked biomaterial or a crosslinked medical device coating.Type: ApplicationFiled: August 21, 2006Publication date: March 1, 2007Applicant: Medtronic, Inc.Inventors: James Keogh, Paul Trescony
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Publication number: 20070020248Abstract: The present invention provides an electrophoretic system, apparatus, and method of use thereof for the preparation of a tissue-derived bioprosthesis.Type: ApplicationFiled: March 1, 2006Publication date: January 25, 2007Inventors: Frank Everaerts, Mark Torrianni, Frans Everaerts, Paul Trescony, Wilfred Hartog
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Publication number: 20060210596Abstract: Apparatus and methods for seeding an implantable medical device, such as a vascular prosthesis, with cells, such as endothelial cells, are described. The invention supports techniques for seeding a luminal surface of the device with axial centrifugation. Cells are introduced in suspension into the lumen of the device. The introduction of the cells may occur after a blood centrifugation product, such as platelet-poor plasma, is applied to the luminal surface. After the cells are introduced, the device is then subjected to centrifugation around a longitudinal axis defined by the lumen. Axial centrifugation causes the cells to concentrate toward and adhere to the luminal surface. Shortly after axial centrifugation, the seeded device can be presented for implantation in a patient. The implantable medical device may be inserted into a protective sleeve prior to seeding the device with cells, and the sleeve may or may not be removed prior to implantation.Type: ApplicationFiled: March 2, 2006Publication date: September 21, 2006Applicant: Medtronic, Inc.Inventors: Michael Wolf, Laurie Yunker, Paul Trescony
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Publication number: 20060199265Abstract: The invention is directed to apparatus and methods for seeding an implantable medical device, such as a vascular prosthesis, with cells, such as endothelial cells. The invention supports techniques for seeding a luminal surface of the device with axial centrifugation. Cells are introduced in suspension into the lumen of the device, and the device is subjected to centrifugation around a longitudinal axis defined by the lumen. Axial centrifugation causes the cells to concentrate toward the luminal surface. Shortly after axial centrifugation, the seeded device can be presented for implantation in a patient.Type: ApplicationFiled: March 2, 2005Publication date: September 7, 2006Inventors: Michael Wolf, Laurie Yunker, Paul Trescony
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Publication number: 20060193968Abstract: A method for making a medical device having at least one biomolecule immobilized on a substrate surface is provided. One method of the present invention includes immobilizing a biomolecule comprising an unsubstituted amide moiety on a biomaterial surface. Another method of the present invention includes immobilizing a biomolecule on a biomaterial surface comprising an unsubstituted amide moiety. Still another method of the present invention may be employed to crosslink biomolecules comprising unsubstituted amide moieties immobilized on medical device surfaces. Additionally, one method of the present invention may be employed to crosslink biomolecules comprising unsubstituted amide moieties in solution, thereby forming a crosslinked biomaterial or a crosslinked medical device coating.Type: ApplicationFiled: April 26, 2006Publication date: August 31, 2006Inventors: James Keogh, Paul Trescony
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Publication number: 20060184235Abstract: In general, the invention is directed to devices and methods that are useful for surface preparation of implantable medical devices. In the case of a vascular graft, the invention presents devices and methods that enhance endothelial cell seeding by providing recesses in the luminal surface that can receive endothelial cells. When the device is constructed of a material such as expanded polytetrafluoroethylene (ePTFE), the recesses may be created by physical processing of the microstructures of the material. The physical processing lifts nodes from the surface, forming recesses that can receive endothelial cells.Type: ApplicationFiled: April 12, 2006Publication date: August 17, 2006Inventors: Nicolas Rivron, Paul Trescony, Michael Wolf
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Publication number: 20060099326Abstract: A method for making a medical device having at least one biomolecule immobilized on a substrate surface is provided. One method of the present invention includes immobilizing a biomolecule comprising an unsubstituted amide moiety on a biomaterial surface. Another method of the present invention includes immobilizing a biomolecule on a biomaterial surface comprising an unsubstituted amide moiety. Still another method of the present invention may be employed to crosslink biomolecules comprising unsubstituted amide moieties immobilized on medical device surfaces. Additionally, one method of the present invention may be employed to crosslink biomolecules comprising unsubstituted amide moieties in solution, thereby forming a crosslinked biomaterial or a crosslinked medical device coating.Type: ApplicationFiled: December 7, 2005Publication date: May 11, 2006Inventors: James Keogh, Paul Trescony
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Publication number: 20050143729Abstract: A device for ablating tissue is provided. The device comprises a conductive element with a channel for irrigating fluid formed therein, which is in contact with a non-conductive microporous interface. All or a portion of the interface may be removable. When the interface is removed, a portion of the conductive element is exposed for use in ablating tissue. Methods of using the device and of removing the interface are also provided.Type: ApplicationFiled: February 18, 2005Publication date: June 30, 2005Inventors: David Francischelli, Richard Comben, Michael Hoey, Rahul Mehra, Jon Ocel, Robert Pearson, Paul Trescony, Scott Jahns
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Publication number: 20050055085Abstract: In general, the invention is directed to devices and methods that are useful for surface preparation of implantable medical devices. In the case of a vascular graft, the invention presents devices and methods that enhance endothelial cell seeding by providing recesses in the luminal surface that can receive endothelial cells. When the device is constructed of a material such as expanded polytetrafluoroethylene (ePTFE), the recesses may be created by physical processing of the microstructures of the material. The physical processing lifts nodes from the surface, forming recesses that can receive endothelial cells.Type: ApplicationFiled: September 4, 2003Publication date: March 10, 2005Inventors: Nicolas Rivron, Paul Trescony, Michael Wolf
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Patent number: 5994444Abstract: A polymeric material formed from a biodegradable polymer matrix is impregnated with a nitric oxide donor for continuous release of nitric oxide upon hydration.Type: GrantFiled: October 16, 1997Date of Patent: November 30, 1999Assignee: Medtronic, Inc.Inventors: Paul Trescony, Ken Rohly, Michael Dror
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Patent number: 5102402Abstract: Balloon catheters are prepared to include a coating of body affecting chemicals on the exterior of the balloon. The coating releases from the balloon when the balloon is inflated into contact with the lumen to be treated. The device provides accurate placement of the dosage required at the location in need of treatment. The coating preferably includes drugs in microcapsules or microspheres. The catheters are especially useful in balloon angioplasty procedures.Type: GrantFiled: January 4, 1991Date of Patent: April 7, 1992Assignee: Medtronic, Inc.Inventors: Michael Dror, Paul Trescony