Patents by Inventor Paul Trubiano

Paul Trubiano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6086917
    Abstract: The present invention is directed to a tablet, particularly a pharmaceutical dosage form, which contains an encapsulating agent comprising a modified starch which is prepared by enzymatic hydrolysis of a starch molecule after the preparation of a starch derivative containing a hydrophobic group or both a hydrophobic and a hydrophilic group, particularly octenyl succinic anhydride starch hydrolyzed by .beta.-amylase or glucoamylase. Such starch allows for good compressibility and hardness of a pharmaceutical dosage form. In addition, the starch may consistently allow for high load and retention of a variety of active agents as well as oxidative resistance.
    Type: Grant
    Filed: October 23, 1998
    Date of Patent: July 11, 2000
    Assignee: National Starch and Chemical Investment Holding Corporation
    Inventors: Paul Trubiano, Dennis Boyd
  • Patent number: 5935826
    Abstract: The present invention relates to modified starches which are prepared by enzymatic hydrolysis of a starch molecule using glucoamylase after the preparation of a starch derivative containing a hydrophobic group or both a hydrophobic and a hydrophilic group, particularly octenyl succinic anhydride starch hydrolyzed by glucoamylase. Such modified starches are useful as emulsifying and/or encapsulating agents, particularly in systems where high load and retention of the active ingredient, low surface oil exposure, and excellent oxidation resistance is desired.
    Type: Grant
    Filed: October 31, 1997
    Date of Patent: August 10, 1999
    Assignee: National Starch and Chemical Investment Holding Corporation
    Inventors: Emily Keller Blue, Chung-Wai Chiu, Zahera Hussain, Himanshu Shah, Paul Trubiano