Abstract: A mechanical cut-off apparatus of a high-voltage electric circuit includes: in a main electrical path a main mechanical switch; in a secondary electrical path, a secondary mechanical switch; a mechanical control configured such that, the secondary mechanical switch is brought to its mechanically open state after the main mechanical switch has been brought to its mechanically open state; the apparatus includes a transition dipole comprising a capacitance, the transition dipole arranged in series with the pair of secondary electrical contacts in the secondary electrical path, and in that the apparatus includes a controlled switch which, in an electrically closed state, creates inside the mechanical cut-off apparatus a bypass that short-circuits the capacitance of the transition dipole.

Abstract: The present invention relates to a device (1) for measuring a magnetic field (B) and/or an electric field (E) comprising:—a measurement cell (3) enclosing a gas that is sensitive to the Zeeman effect and/or to the Stark effect, a polarised light source (7) the wavelength of which is tuned to an absorption line of the gas that is sensitive to the Zeeman effect and/or to the Stark effect,—at least one polarimetry system (11) configured to measure a first parameter corresponding to the rotation by a polarisation angle caused by the passage of the beam (9) through the measurement cell (3) enclosing a gas that is sensitive to the Zeeman effect and/or to the Stark effect,—a system (13) for measuring absorption, configured to measure a second parameter corresponding to the absorption of the beam (9) by the gas that is sensitive to the Zeeman effect and/or to the Stark effect in the measurement cell (3), and a processing unit (15) configured to combine the measurement of the first parameter corresponding to the rotat

Abstract: The present invention relates to a device (1) for measuring a magnetic field (B) and/or an electric field (E) comprising:—a measurement cell (3) enclosing a gas that is sensitive to the Zeeman effect and/or to the Stark effect, a polarised light source (7) the wavelength of which is tuned to an absorption line of the gas that is sensitive to the Zeeman effect and/or to the Stark effect,—at least one polarimetry system (11) configured to measure a first parameter corresponding to the rotation by a polarisation angle caused by the passage of the beam (9) through the measurement cell (3) enclosing a gas that is sensitive to the Zeeman effect and/or to the Stark effect,—a system (13) for measuring absorption, configured to measure a second parameter corresponding to the absorption of the beam (9) by the gas that is sensitive to the Zeeman effect and/or to the Stark effect in the measurement cell (3), and a processing unit (15) configured to combine the measurement of the first parameter corresponding to the rotat

Abstract: A mechanical breaker apparatus for breaking an electric circuit comprises two electrodes that are movable relative to each other, and including an electric arc splitter device having a multitude of distinct conductive elements that are spaced apart and electrically insulated relative to one another. The splitter device has a first portion and a second portion that are movable relative to each other between: an electrical contact position; and a spaced-apart position of the two portions. The splitter device has at least one series of the distinct conductive elements that, in an electrically closed position of the electrodes of the mechanical apparatus, are arranged along the continuous electrically-conductive path for the nominal electric current through the apparatus as defined by the two portions of the splitter device in the electrical contact position.

Abstract: A mechanical breaker apparatus for breaking an electric circuit comprises two electrodes that are movable relative to each other, and including an electric arc splitter device having a multitude of distinct conductive elements that are spaced apart and electrically insulated relative to one another. The splitter device has a first portion and a second portion that are movable relative to each other between: an electrical contact position; and a spaced-apart position of the two portions. The splitter device has at least one series of the distinct conductive elements that, in an electrically closed position of the electrodes of the mechanical apparatus, are arranged along the continuous electrically-conductive path for the nominal electric current through the apparatus as defined by the two portions of the splitter device in the electrical contact position.

Abstract: A mechanical breaker apparatus for breaking an electric circuit comprises two electrodes that are movable relative to each other, and including an electric arc splitter device having a multitude of distinct conductive elements that are spaced apart and electrically insulated relative to one another. The splitter device has a first portion and a second portion that are movable relative to each other between: an electrical contact position; and a spaced-apart position of the two portions. The splitter device has at least one series of the distinct conductive elements that, in an electrically closed position of the electrodes of the mechanical apparatus, are arranged along the continuous electrically-conductive path for the nominal electric current through the apparatus as defined by the two portions of the splitter device in the electrical contact position.

Abstract: A medium- or high-voltage switch (10), comprising a high-vacuum enclosure (111); first and second contacts (121, 122) that are mounted to be movable in translation relative to each other inside the enclosure (111) between an open position in which the first and second contacts (121, 122) are spaced apart; and a closed position in which the first and second contacts (121, 122) are in electrical contact. The switch (10) further comprises a conductor (210, 220, 230) arranged inside the enclosure (111) in such a manner that there exists a pressure threshold inside the enclosure (111) from which partial discharges are generated by said conductor, at least when the first and second contacts (121, 122) are in the closed position and the medium or high voltage is applied to the switch (10). The invention further relates to a switch assembly and to a method of testing such a switch.

Abstract: A mechanical breaker apparatus for breaking an electric circuit comprises two electrodes that are movable relative to each other, and including an electric arc splitter device having a multitude of distinct conductive elements that are spaced apart and electrically insulated relative to one another. The splitter device has a first portion and a second portion that are movable relative to each other between: an electrical contact position; and a spaced-apart position of the two portions. The splitter device has at least one series of the distinct conductive elements that, in an electrically closed position of the electrodes of the mechanical apparatus, are arranged along the continuous electrically-conductive path for the nominal electric current through the apparatus as defined by the two portions of the splitter device in the electrical contact position.

Abstract: A medium- or high-voltage switch (10), comprising a high-vacuum enclosure (111); first and second contacts (121, 122) that are mounted to be movable in translation relative to each other inside the enclosure (111) between an open position in which the first and second contacts (121, 122) are spaced apart; and a closed position in which the first and second contacts (121, 122) are in electrical contact. The switch (10) further comprises a conductor (210, 220, 230) arranged inside the enclosure (111) in such a manner that there exists a pressure threshold inside the enclosure (111) from which partial discharges are generated by said conductor, at least when the first and second contacts (121, 122) are in the closed position and the medium or high voltage is applied to the switch (10). The invention further relates to a switch assembly and to a method of testing such a switch.

Abstract: The present invention provides a specific binding molecule which specifically binds to a peptide having the amino acid sequence of EDGIKRIQDD and comprises a polypeptide having an immunoglobulin VL domain linked to an immunoglobulin VH domain in which the VL domain comprises Complementarity Determining Regions (CDRs) VLCDR1, VLCDR2 and VLCDR3, and in which the VH domain comprises Complementarity Determining Regions (CDRs) VHCDR1, VHCDR2, VHCDR3, each having a respective amino acid sequence as follows in which VHCDR1 is GYSFTGYNMN VHCDR2 is NIDPYYGGTTYNQKFKG VHCDR3 is EVDY VLCDR1 is RASKSVSTSTSGYSYMH VLCDR2 is LVSNLES VLCDR3 is QHIRELTRSEG or an amino acid sequence at least 70% identical thereto.

Abstract: The present invention provides a specific binding molecule which specifically binds to a peptide having the amino acid sequence of EDGIKRIQDD and comprises a polypeptide having an immunoglobulin VL domain linked to an immunoglobulin VH domain in which the VL domain comprises Complementarity Determining Regions (CDRs) VLCDR1, VLCDR2 and VLCDR3, and in which the VH domain comprises Complementarity Determining Regions (CDRs) VHCDR1, VHCDR2, VHCDR3, each having a respective amino acid sequence as follows in which VHCDR1 is GYSFTGYNMN VHCDR2 is NIDPYYGGTTYNQKFKG VHCDR3 is EVDY VLCDR1 is RASKSVSTSTSGYSYMH VLCDR2 is LVSNLES VLCDR3 is QHIRELTRSEG or an amino acid sequence at least 70% identical thereto.

Abstract: The use of monoclonal antibodies to the angiotensin-II type-I receptor is provided for the treatment of cancer and vascular smooth muscle cell proliferation. Specifically, use is provided of a monoclonal antibody or a fragment thereof to a peptide comprising the N-terminal portion of the angiotensin-II type-1 receptor defined by the sequence (SEQ?ID?NO:?1) MILNSSTEDG?IKRIQDDCPK?AGRHNYIFVM?IPTLYSIIFV?VGIFG in the preparation of a medicament for the treatment of cancer or in the preparation of a medicament for the treatment of vascular smooth muscle (VSM) cell proliferation.

Abstract: The present invention provides a specific binding molecule which specifically binds to a peptide having the amino acid sequence of EDGIKRIQDD and comprises a polypeptide having an immunoglobulin VL domain linked to an immunoglobulin VH domain in which the VL domain comprises Complementarity Determining Regions (CDRs) VLCDR1, VLCDR2 and VLCDR3, and in which the VH domain comprises Complementarity Determining Regions (CDRs) VHCDR1, VHCDR2, VHCDR3, each having a respective amino acid sequence as follows in which VHCDR1?is?GYSFTGYNMN VHCDR2?is?NIDPYYGGTTYNQKFKG VHCDR3?is?EVDY VLCDR1?is?RASKSVSTSTSGYSYMH VLCDR2?is?LVSNLES VLCDR3?is?QHIRELTRSEG or an amino acid sequence at least 70% identical thereto.

Abstract: The use of monoclonal antibodies to the angiotensin-II type-I receptor is provided for the treatment of cancer and vascular smooth muscle cell proliferation. Specifically, use is provided of a monoclonal antibody or a fragment thereof to a peptide comprising the N-terminal portion of the angiotensin-II type-1 receptor defined by the sequence MILNSSTEDG IKRIQDDCPK AGHRHNYIFVM IPTLYSIIFV VGIFG in the preparation of a medicament for the treatment of cancer or in the preparation of a medicament for the treatment of vascular smooth muscle (VSM) cell proliferation.

Abstract: The use of monoclonal antibodies to the angiotensin-II type-I receptor is provided for the treatment of cancer and vascular smooth muscle cell proliferation. Specifically, use is provided of a monoclonal antibody or a fragment thereof to a peptide comprising the N-terminal portion of the angiotensin-II type-1 receptor defined by the sequence MILNSSTEDG IKRIQDDCPK AGHRHNYIFVM IPTLYSIIFV VGIFG in the preparation of a medicament for the treatment of cancer or in the preparation of a medicament for the treatment of vascular smooth muscle (VSM) cell proliferation.

Abstract: The use of monoclonal antibodies to the angiotensin-II type-I receptor is provided for the treatment of cancer and vascular smooth muscle cell proliferation. Specifically, use is provided of a monoclonal antibody or a fragment thereof to a peptide comprising the N-terminal portion of the angiotensin-II type-1 receptor defined by the sequence MILNSSTEDG IKRIQDDCPK AGRHNYIFVM IPTLYSIIFV VGIFG in the preparation of a medicament for the treatment of cancer or in the preparation of a medicament for the treatment of vascular smooth muscle (VSM) cell proliferation.

Abstract: The present invention provides a specific binding molecule which specifically binds to a peptide having the amino acid sequence of EDGIKRIQDD and comprises a polypeptide having an immunoglobulin VL domain linked to an immunoglobulin VH domain in which the VL domain comprises Complementarity Determining Regions (CDRs) VLCDR1, VLCDR2 and VLCDR3, and in which the VH domain comprises Complementarity Determining Regions (CDRs) VHCDR1, VHCDR2, VHCDR3, each having a respective amino acid sequence as follows in which VHCDR1?is?GYSFTGYNMN VHCDR2?is?NIDPYYGGTTYNQKFKG VHCDR3?is?EVDY VLCDR1?is?RASKSVSTSTSGYSYMH VLCDR2?is?LVSNLES VLCDR3?is?QHIRELTRSEG or an amino acid sequence at least 70% identical thereto.

Abstract: The present invention relates to the use of angiotensin in a method for the treatment or prevention of cancer. The method comprises administering to a patient in need of treatment an effective amount of an angiotensin.

Abstract: The present invention relates to a novel hybridoma cell line which secretes monoclonal antibodies capable of binding to the AT1 subtype of the Angiotensin II receptor. It also relates to monoclonal antibodies secreted by the hybridoma, which antibodies may be used in diagnostic test kits as well as having therapeutic applications.

Abstract: The invention concerns a pluviometric device for measuring the diameter of individual raindrops (G) passing through a measuring volume (110), comprising optical transmission means (100), receiving means including at least a sensor receiving at least part of the light derived from at least one transmission means after it has passed through the measuring volume, and processing means (20, 30) which receive the signal at said sensor (120) output and which determine the individual diameter of raindrops. The invention is characterized in that the receiving means include at least two such sensors (124a, 124b) which receive portions of light derived from the transmitting means which are superposed along the general displacement direction of the particles and the processing means (20, 30) operate a correlative processing on the signals at the output of said sensors.