Patents by Inventor Paula M. KOELLE

Paula M. KOELLE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions, methods and devices comprising stem-loop captor molecules
    Patent number: 11713482
    Abstract: Disclosed herein are methods, devices and compositions comprising nucleic acid captor molecules with a stem region and a loop region for detecting target nucleic acids.
    Type: Grant
    Filed: June 15, 2017
    Date of Patent: August 1, 2023
    Assignee: GENECAPTURE, INC.
    Inventors: Paula M. Koelle, Krishnan Chittur, Valentin Korman, Zachary McGee
  • METHODS AND SYSTEMS FOR DETERMINING TARGET SENSITIVITY TO A THERAPEUTIC FORMULA
    Publication number: 20220111378
    Abstract: Systems and methods are disclosed herein for determining the sensitivity of a target to a therapeutic formula. The systems include a measurement device for measuring properties of a target sample fluid housed within a cartridge (the cartridge having at least one test compartment and at least one control compartment). Methods can include determining the concentration of the target suspended in a target sample fluid and placing the target sample fluid into at least one test compartment comprising a first therapeutic formula. The system, via a processor, measures the properties of the sample fluid, compares the measured properties to a threshold property, determines the sensitivity of a target species to a therapeutic formula, and presents an indicator of the target sensitivity to an end user. In some embodiments, the sensitivity data can be stored to a database for later use by an adaptive machine learning tool.
    Type: Application
    Filed: January 17, 2020
    Publication date: April 14, 2022
    Inventors: Paula M. KOELLE, Krishnan CHITTUR, Zachary MCGEE, Thomas M. CANTEY, Valentin KORMAN, Greg THOMPSON
  • COMPOSITIONS, METHODS AND DEVICES COMPRISING STEM-LOOP CAPTOR MOLECULES
    Publication number: 20200354779
    Abstract: Disclosed herein are methods, devices and compositions comprising nucleic acid captor molecules with a stem region and a loop region for detecting target nucleic acids.
    Type: Application
    Filed: June 15, 2017
    Publication date: November 12, 2020
    Inventors: Paula M. KOELLE, Krishnan CHITTUR, Valentin KORMAN, Zachary McGEE