Patents by Inventor Paula T. Hammond

Paula T. Hammond has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200046760
    Abstract: Disclosed herein are polymers containing repeating units of formula (I) or copolymers containing the repeating units of formula (I) and (II), where R1 to R12, m, n, p, q, x and y are as defined herein. The polymers and copolymers have an antimicrobial effect and may be used therapeutically or in formulations intended for use as detergents.
    Type: Application
    Filed: April 18, 2017
    Publication date: February 13, 2020
    Inventors: Bee Eng Mary CHAN, Paula T. HAMMOND, Bo LIU, Wenbin ZHONG
  • Publication number: 20200052300
    Abstract: The present disclosure provides a composite material comprising an electrically conductive polymer, such as poly(3,4-ethylenedioxythiophene) (PEDOT) and an ionically conductive polymer, such as poly(ethylene oxide) (PEO). This composite forms a dual conductor for three-dimensional electrodes in electrochemical applications including lithium ion batteries.
    Type: Application
    Filed: October 17, 2017
    Publication date: February 13, 2020
    Inventors: Michael McDonald, Paula T. Hammond
  • Patent number: 10535908
    Abstract: A lithium ion conducting protective film produced using a layer-by-layer assembly process. The lithium ion conducting protective film is assembled on a substrate by a sequential exposure of the substrate to a first poly(ethylene oxide) (PEO) layer including a cross-linking silane component on the first side of the substrate, a graphene oxide (GO) layer on the first PEO layer, a second poly(ethylene oxide) (PEO) layer including a cross-linking silane component on the GO layer and a poly(acrylic acid) (PAA) layer on the second PEO layer. The film functions as a lithium ion conducting protective film that isolates the lithium anode from the positive electrochemistry of the cathode in a lithium-air battery, thereby preventing undesirable lithium dendrite growth.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: January 14, 2020
    Assignees: SAMSUNG ELECTRONICS CO., LTD., MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Mariya Khiterer, Paula T. Hammond, Sun Hwa Lee
  • Publication number: 20200000713
    Abstract: A pharmaceutical composition, comprising a particle (micro-depot) that includes silk fibroin and at least one active pharmaceutical ingredient (API). The particle can be suspended in carboxymethyl cellulose to form an injectable pharmaceutical composition.
    Type: Application
    Filed: January 19, 2018
    Publication date: January 2, 2020
    Inventors: Nitasha Bennett, Darrell J. Irvine, Paula T. Hammond
  • Patent number: 10278927
    Abstract: Systems and methods for coating a particle core with a layer-by-layer film are disclosed.
    Type: Grant
    Filed: April 23, 2013
    Date of Patent: May 7, 2019
    Assignee: Massachusetts Institute of Technology
    Inventors: Paula T. Hammond, Zhiyong Poon
  • Publication number: 20190125895
    Abstract: Disclosed are particles for delivering cytokinese, such as IL-12, for the treatment of cancer. The particles comprise cytokines non-covalently bound to liposomes, where the liposomes are coated with polyelectrolytes.
    Type: Application
    Filed: October 30, 2018
    Publication date: May 2, 2019
    Inventors: Antonio Eric Barberio, Santiago Correa Echavarria, Mariane Bandeira Melo, Talar Tokatlian, Erik Christopher Dreaden, Paula T. Hammond, Darrell J. Irvine
  • Patent number: 10276309
    Abstract: A dye-sensitized solar cell can include a plurality of a plasmon-forming nanostructures. The plasmon-forming nanostructures can include an oxide core, an inner metallic shell on a surface of the oxide core, and an outer oxide shell on a surface of the inner metallic shell.
    Type: Grant
    Filed: October 8, 2013
    Date of Patent: April 30, 2019
    Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Jifa Qi, Xiangnan Dang, Angela M. Belcher, Paula T. Hammond
  • Patent number: 10256516
    Abstract: Provided are electrochemical cells that include a compound having the general formula wherein R1 is moiety associated with a lithium ion, X1 and X3 are unsubstituted methylene moieties, X2 and X4 are each independently selected from a substituted or unsubstituted methylene moiety, X is a substituted or unsubstituted C1-C10 alkylene moiety, arylene moiety or heteroarylene moiety, R2 is selected from Li, H, an alkyl moiety, or a heteroalkyl moiety, 0<m?1, 0?n?1, and m+n=1.
    Type: Grant
    Filed: November 23, 2015
    Date of Patent: April 9, 2019
    Assignees: SAMSUNG ELECTRONICS CO., LTD., MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Sang Bok Ma, Mariya Khiterer, Young-Gyoon Ryu, Paula T. Hammond, Yang Shao-Horn, Chibueze Vincent Amanchukwu
  • Patent number: 10199588
    Abstract: A planar mixed-metal perovskite solar cell can exhibit many favorable properties including high efficiencies and tunable electronic properties. The incorporation of different metal species (i.e. Co, Cu, Fe, Mg, Mn, Ni, Sn, Sr, and Zn) into the film is made possible by the solubility of either each metal's divalent acetate or halide compound in a solvent.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: February 5, 2019
    Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Angela M. Belcher, Matthew T. Klug, Paula T. Hammond
  • Publication number: 20180326092
    Abstract: The invention relates to methods of improving efficacy and enhancing silencing of target genes using Ago2 protein-dsRNA complex (RNP) of the invention.
    Type: Application
    Filed: May 11, 2018
    Publication date: November 15, 2018
    Inventors: Jiahe Je, Paula T. Hammond, Yanpu He, Wade Wang
  • Patent number: 10074839
    Abstract: Battery separators for lithium-air batteries are provided. In some embodiments, a lithium-air battery may comprise one or more electrochemical cells including an anode, a cathode, an electrolyte, and a battery separator positioned between the anode and the cathode. The battery separator may comprise a porous membrane having a lithium ion conductive film on at least a portion of the porous membrane. The lithium ion conductive film may comprise layers designed to impart beneficial properties to the porous membrane and/or battery, such as resistance to dendrite formation, while having relatively minimal or no adverse effects on one or more important properties of the porous membrane (e.g., ionic conductivity, electrolyte permeability, weight, mechanical stability) and/or the overall battery.
    Type: Grant
    Filed: July 26, 2016
    Date of Patent: September 11, 2018
    Assignee: Massachusetts Institute of Technology
    Inventors: Paula T. Hammond-Cunningham, Sun Hwa Lee
  • Publication number: 20180185513
    Abstract: Disclosed herein are conjugated polymers comprising a polymer and an all-trans retinoic acid (ATRA) prodrug covalently bound to the polymer by a hydrolysable linker L or a pharmaceutically acceptable salt thereof, and methods of using same to treat certain disorders. In an embodiment, the conjugated polymer comprises poly (vinyl alcohol) covalently bound to ATRA through an ester linkage.
    Type: Application
    Filed: June 23, 2016
    Publication date: July 5, 2018
    Inventors: Steven A. CASTLEBERRY, Mohiuddin A. QUADIR, Paula T. HAMMOND
  • Publication number: 20180034031
    Abstract: Battery separators for lithium-air batteries are provided. In some embodiments, a lithium-air battery may comprise one or more electrochemical cells including an anode, a cathode, an electrolyte, and a battery separator positioned between the anode and the cathode. The battery separator may comprise a porous membrane having a lithium ion conductive film on at least a portion of the porous membrane. The lithium ion conductive film may comprise layers designed to impart beneficial properties to the porous membrane and/or battery, such as resistance to dendrite formation, while having relatively minimal or no adverse effects on one or more important properties of the porous membrane (e.g., ionic conductivity, electrolyte permeability, weight, mechanical stability) and/or the overall battery.
    Type: Application
    Filed: July 26, 2016
    Publication date: February 1, 2018
    Applicant: Massachusetts Institute of Technology
    Inventors: Paula T. Hammond-Cunningham, Sun Hwa Lee
  • Publication number: 20170365900
    Abstract: A lithium ion conducting protective film produced using a layer-by-layer assembly process. The lithium ion conducting protective film is assembled on a substrate by a sequential exposure of the substrate to a first poly(ethylene oxide) (PEO) layer including a cross-linking silane component on the first side of the substrate, a graphene oxide (GO) layer on the first PEO layer, a second poly(ethylene oxide) (PEO) layer including a cross-linking silane component on the GO layer and a poly(acrylic acid) (PAA) layer on the second PEO layer. The film functions as a lithium ion conducting protective film that isolates the lithium anode from the positive electrochemistry of the cathode in a lithium-air battery, thereby preventing undesirable lithium dendrite growth.
    Type: Application
    Filed: June 29, 2017
    Publication date: December 21, 2017
    Inventors: Mariya Khiterer, Paula T. Hammond, Sun Hwa Lee
  • Patent number: 9805841
    Abstract: Virus multilayers can be used as templates for growth of inorganic nanomaterials. For example, layer-by-layer construction of virus multilayers on functionalized surfaces form nanoporous structures onto which metal particles or metal oxide nanoparticles can be nucleated to result in an interconnected network of nanowires.
    Type: Grant
    Filed: July 3, 2013
    Date of Patent: October 31, 2017
    Assignee: Massachusetts Institute of Technology
    Inventors: Noemie-Manuelle Dorval Courchesne, Angela M. Belcher, Paula T. Hammond, Matthew T. Klug
  • Publication number: 20170258738
    Abstract: The present invention provides, among other things, multilayer film coating compositions, coated substrates and methods thereof. In some embodiments, a structure, comprising a substrate and a multilayer film on the substrate, wherein the multilayer film comprises a release layer and one or more layer-by-layer films. In some embodiments, a structure comprising a microneedle substrate and a multilayer film coated on at least portion of the microneedle substrate, wherein the multilayer film comprises an agent for delivery.
    Type: Application
    Filed: February 21, 2017
    Publication date: September 14, 2017
    Inventors: Peter C. DeMuth, Younjin Min, Darrell Irvine, Paula T. Hammond
  • Patent number: 9737557
    Abstract: The present invention provides, among other things, a particle which includes a core comprised of self-assembled one or more nucleic acid molecules, the core being characterized by an ability to adopt at least two configurations: a first configuration having a first greatest dimension greater than 2 ?m and; a second configuration having a second greatest dimension less than 500 nm, wherein addition of a film coating converts the core from its first configuration to its second configuration. Methods of making and using of provided particles are also disclosed.
    Type: Grant
    Filed: July 28, 2015
    Date of Patent: August 22, 2017
    Assignee: Massachusetts Institute of Technology
    Inventors: Paula T. Hammond, Jong Bum Lee, Young Hoon Roh
  • Patent number: 9705167
    Abstract: A lithium ion conducting protective film is produced using a layer-by-layer assembly process. The lithium ion conducting protective film is assembled on a substrate by a sequential exposure of the substrate to a first poly(ethylene oxide) (PEO) layer including a cross-linking silane component on the first side of the substrate, a graphene oxide (GO) layer on the first PEO layer, a second poly(ethylene oxide) (PEO) layer including a cross-linking silane component on the GO layer and a poly(acrylic acid) (PAA) layer on the second PEO layer, The film functions as a lithium ion conducting protective film that isolates the lithium anode from the positive electrochemistry of the cathode in a lithium-air battery, thereby preventing undesirable lithium dendrite growth.
    Type: Grant
    Filed: December 6, 2013
    Date of Patent: July 11, 2017
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Mariya Khiterer, Paula T. Hammond, Sun Hwa Lee
  • Publication number: 20170181981
    Abstract: A multi-layer film useful for controlled drug delivery is described. The multilayer film is peelable and self-supporting.
    Type: Application
    Filed: December 28, 2016
    Publication date: June 29, 2017
    Inventors: Paula T. Hammond, Bryan Boen Hsu, Samantha R. Hagerman
  • Publication number: 20170149104
    Abstract: Provided are electrochemical cells that include a compound having the general formula wherein R1 is moiety associated with a lithium ion, X1 and X3 are unsubstituted methylene moieties, X2 and X4 are each independently selected from a substituted or unsubstituted methylene moiety, X is a substituted or unsubstituted C1-C10 alkylene moiety, arylene moiety or heteroarylene moiety, R2 is selected from Li, H, an alkyl moiety, or a heteroalkyl moiety, 0<m?1, 0?n?1, and m+n=1.
    Type: Application
    Filed: November 23, 2015
    Publication date: May 25, 2017
    Inventors: Sang Bok Ma, Mariya Khiterer, Young-Gyoon Ryu, Paula T. Hammond, Yang Shao-Horn, Chibueze Vincent Amanchukwu