Abstract: The invention is directed to novel probiotic bacterial strains that colonize animal tissues, and in particular the gastrointestinal (GI) tract of aquatic animals grown in aquaculture environments and may further be engineered to express and deliver interfering RNA molecules configured to downregulate expression of one or more pathogen, or endogenous host genes.

Abstract: The inventive technology includes novel systems, methods, and compositions for the generation of genetically engineered prokaryotic organisms configured to produce eukaryotic-like mRNA that may be introduced to, and translated in a eukaryotic host. Additional aspects may include novel eukaryotic-like nucleotide constructs and mRNA molecules, as well as methods and systems for the efficient delivery from prokaryotic cells to target eukaryotic hosts cells. Still further aspects of the invention include systems, methods and compositions for the the non-integrative transformation of eukaryotic cell.

Abstract: A memory dispatcher, including an address decoder configured to decode a write address of received write data; a lockstep processor configured to generate, based on the decoded write address, primary and redundant memory write addresses and corresponding primary and redundant copies of the write data, if the decoded write address corresponds with a lockstep region of the memory; and a comparator coupled to the lockstep processor, and configured to compare the primary and redundant copies of the write data, and to compare the primary and redundant memory write addresses.

Abstract: An articulation rigidity assessment device comprises a single-axis angular velocity sensor attachable to a limb such that an axis of measurement is parallel to a predetermined rotation axis of a bending motion imposed during a dosage administration regime of a drug in order to identify a clinically effective dose as having been administered. A data processor is configured to process an angular velocity sensor signal during the dosage administration, calculate a non-rigidity index of the articulation using the processed signal, wherein the non-rigidity index is the square root of the multiplication of the average of the angular velocity signal by the average peak value of the angular velocity signal. The device outputs feedback of the non-rigidity index at a current dose of the drug, whereby the clinically effective dose is identified as having been administered as a function of the output. A method is also disclosed.

Abstract: A device for accessing memory configured to store an image data cube, wherein the memory has memory banks, and each memory bank has memory rows and memory columns. The device includes an input configured to receive a memory access request having a logical start address, which specifies a logical bank, a logical row, and a logical column, and a burst size; and a memory address generator configured to generate physical memory addresses based on the logical start address and the burst size, wherein any consecutive logical start addresses mapped to different memory rows are mapped to different memory banks.

Abstract: It is disclosed an articulation rigidity assessment device for assessing the rigidity of the articulation when a bending motion is imposed to a limb of said articulation around a predetermined rotation axis of the articulation, said device comprising: a one-axis angular velocity sensor for attaching to said limb such that the axis of measurement is parallel to the axis of rotation of the imposed bending motion; a data processor configured to process the signal of the angular velocity sensor and to distinguish between non-rigid and rigid states of the articulation using the processed angular velocity signal. The articulation may be the wrist articulation of the patient and the limb is the respective hand. The device may comprise a skin-contacting patch for applying to the limb of the patient wherein the one-axis angular velocity sensor is attached to said skin-contacting patch. The skin-contacting patch may be applied to the palm or back of the hand.

Abstract: A memory dispatcher, including an address decoder configured to decode a write address of received write data; a lockstep processor configured to generate, based on the decoded write address, primary and redundant memory write addresses and corresponding primary and redundant copies of the write data, if the decoded write address corresponds with a lockstep region of the memory; and a comparator coupled to the lockstep processor, and configured to compare the primary and redundant copies of the write data, and to compare the primary and redundant memory write addresses.

Abstract: A device for accessing memory configured to store an image data cube, wherein the memory has memory banks, and each memory bank has memory rows and memory columns. The device includes an input configured to receive a memory access request having a logical start address, which specifies a logical bank, a logical row, and a logical column, and a burst size; and a memory address generator configured to generate physical memory addresses based on the logical start address and the burst size, wherein any consecutive logical start addresses mapped to different memory rows are mapped to different memory banks.

Abstract: The inventive technology may include novel systems for regulation of the expression of bacterial genes through the introduction of antisense RNA (asRNA) that may disrupt expression of targeted pathogenic genes and/or their products (mRNA, proteins). In some embodiments, the inventive technology may include novel genetically engineered donor bacterial strains that are configured to efficiently and continuously deliver asRNA polynucleotides to a recipient pathogen and downregulate expression or one or more essential genes.

Abstract: The inventive technology relates to novel systems, methods, and strategies for the control of plant pathogens and herbivores. The inventive technology may specifically include novel compositions, systems, and methods configured to deliver inhibitory RNA molecules to a pathogen-infected plant. In a preferred embodiment, the invention may include genetically engineered endophytic bacteria configured to deliver one or more inhibitory RNA molecules to a pathogen-infected plant. One preferred embodiment may include a novel trans-kingdom delivery of hairpin RNA targeting viral encoded proteins resulting in the reduction of viral protein accumulation levels.

Abstract: A modulator having a pulse density modulator configured to generate from bit stream information a Pulse Density Modulation (PDM) stream based on a PDM clock; and a bit stream adjuster configured to divide the PDM clock into a PDM multi-phase clock, adjust a duration of at least one pulse of the generated PDM stream by selecting a PDM clock phase of the PDM multi-phase clock for sampling the generated PDM stream, and output an adjusted PDM stream.

Abstract: A modulator having a pulse density modulator configured to generate from bit stream information a Pulse Density Modulation (PDM) stream based on a PDM clock; and a bit stream adjuster configured to divide the PDM clock into a PDM multi-phase clock, adjust a duration of at least one pulse of the generated PDM stream by selecting a PDM clock phase of the PDM multi-phase clock for sampling the generated PDM stream, and output an adjusted PDM stream.

Abstract: A timer including a Pulse Width Modulation (PWM) signal generator configured to generate, based on a clock, a PWM signal having a first frequency resolution; a PWM time shifter configured to receive from the PWM signal generator the PWM signal having the first frequency resolution, and output a PWM signal having a second frequency resolution, wherein the second frequency resolution is higher than the first frequency resolution; and a control monitor configured to: control the PWM time shifter to time shift rising edges or falling edges of the PWM signal by an amount corresponding with a second frequency resolution.

Abstract: In some examples, a device includes control circuitry configured to receive a first input signal, receive a second input signal, and cause gate driver circuitry to deliver a driver signal to a switch to cause the switch to deliver electrical power to an electrical load. In some examples, the control circuitry is further configured to determine whether the first input signal has an active value and determine whether the second input signal has an active value. In some examples, the control circuitry is also configured to cause the gate driver circuitry to change the driver signal across a switching cycle of the switch to increase or decrease the electrical power delivered by the switch to the electrical load in response to determining that the first input signal has the active value or in response to determining that the second input signal has the active value.

Abstract: A timer including a Pulse Width Modulation (PWM) signal generator configured to generate, based on a clock, a PWM signal having a first frequency resolution; a PWM time shifter configured to receive from the PWM signal generator the PWM signal having the first frequency resolution, and output a PWM signal having a second frequency resolution, wherein the second frequency resolution is higher than the first frequency resolution; and a control monitor configured to: control the PWM time shifter to time shift rising edges or falling edges of the PWM signal by an amount corresponding with a second frequency resolution.

Abstract: It is disclosed an articulation rigidity assessment device for assessing the rigidity of the articulation when a bending motion is imposed to a limb of said articulation around a predetermined rotation axis of the articulation, said device comprising: a one-axis angular velocity sensor for attaching to said limb such that the axis of measurement is parallel to the axis of rotation of the imposed bending motion; a data processor configured to process the signal of the angular velocity sensor and to distinguish between non-rigid and rigid states of the articulation using the processed angular velocity signal. The articulation may be the wrist articulation of the patient and the limb is the respective hand. The device may comprise a skin-contacting patch for applying to the limb of the patient wherein the one-axis angular velocity sensor is attached to said skin-contacting patch. The skin-contacting patch may be applied to the palm or back of the hand.

Abstract: The disclosure generally relates to a method and an apparatus for providing an adjustable high resolution dead time, and more specifically, to a method and an apparatus for inserting an adjustable high resolution dead time in a PWM signal. A method for inserting an adjustable high resolution dead time in a PWM signal includes receiving a clock signal at a delaying circuitry and generating, by the delaying circuitry, a plurality of phases, receiving the generated plurality of phases at a first multiplexer, and selecting and forwarding, by the first multiplexer, a first phase of the plurality of phases based on a first high resolution dead time value. The method further includes shifting a rising edge and/or a falling edge of the PWM signal using the received first phase forwarded by the first multiplexer.