Patents by Inventor Pedro Michael Cavaleiro Miranda

Pedro Michael Cavaleiro Miranda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11642514
    Abstract: When electrodes are used to impose an electric field in target tissue within an anatomic volume (e.g., to apply TTFields to treat a tumor), the position of the electrodes can be optimized by generating a 3D map of electrical conductivity or resistivity of the anatomic volume. A location of the target tissue within the anatomic volume is identified, and a dipole is added to the 3D map at a location that corresponds to the target tissue. positions for the electrodes that maximize a potential attributable to the dipole are determined based on the 3D map of electrical conductivity or resistivity and the location of the dipole.
    Type: Grant
    Filed: March 3, 2021
    Date of Patent: May 9, 2023
    Assignee: Novocure GmbH
    Inventors: Yoram Wasserman, Cornelia Wenger, Pedro Michael Cavaleiro Miranda, Zeev Bomzon, Noa Urman, Eilon Kirson, Yoram Palti
  • Publication number: 20210187277
    Abstract: When electrodes are used to impose an electric field in target tissue within an anatomic volume (e.g., to apply TTFields to treat a tumor), the position of the electrodes can be optimized by generating a 3D map of electrical conductivity or resistivity of the anatomic volume. A location of the target tissue within the anatomic volume is identified, and a dipole is added to the 3D map at a location that corresponds to the target tissue. positions for the electrodes that maximize a potential attributable to the dipole are determined based on the 3D map of electrical conductivity or resistivity and the location of the dipole.
    Type: Application
    Filed: March 3, 2021
    Publication date: June 24, 2021
    Applicant: Novocure GmbH
    Inventors: Yoram WASSERMAN, Cornelia WENGER, Pedro Michael Cavaleiro MIRANDA, Zeev BOMZON, Noa URMAN, Eilon KIRSON, Yoram PALTI
  • Patent number: 11013909
    Abstract: When electrodes are used to impose an electric field in target tissue within an anatomic volume (e.g., to apply TTFields to treat a tumor), the position of the electrodes can be optimized by obtaining electrical conductivity measurements in an anatomic volume and generating a 3D map of the conductivity directly from the obtained electrical conductivity or resistivity measurements, without segmenting the anatomic volume into tissue types. A location of the target tissue is identified within the anatomic volume, and the positions for the electrodes are determined based on the 3D map of electrical conductivity and the position of the target tissue.
    Type: Grant
    Filed: December 17, 2018
    Date of Patent: May 25, 2021
    Assignee: Novocure GmbH
    Inventors: Cornelia Wenger, Pedro Michael Cavaleiro Miranda, Zeev Bomzon, Noa Urman, Eilon Kirson, Yoram Wasserman, Yoram Palti
  • Patent number: 10463855
    Abstract: A system and a method for optimizing the configuration of multisite transcranial current stimulation, including providing an electric field characteristic target map on the brain's cortex, the target map including multiple cortical targets, the multiple cortical targets are localized and/or continuously varying and spatially extended, providing a weight map on the cortical surface prioritizing the important of areas in the target map for the purposes of optimization; and calculating, based on the target and weight maps, optimal currents and optimal locations for a plurality of electrodes intended for providing transcranial current stimulation to globally stimulate at once the multiple cortical targets with excitatory, inhibitory or neutral stimulation.
    Type: Grant
    Filed: May 16, 2017
    Date of Patent: November 5, 2019
    Assignees: NEUROELECTRICS BARCELONA S.L., BETH ISRAEL DEACONESS MEDICAL CENTER
    Inventors: Giulio Ruffini, Oscar Ripolles Mateu, Alvaro Pascual-Leone, Michael D. Fox, Pedro Michael Cavaleiro Miranda
  • Publication number: 20190117956
    Abstract: When electrodes are used to impose an electric field in target tissue within an anatomic volume (e.g., to apply TTFields to treat a tumor), the position of the electrodes can be optimized by obtaining electrical conductivity measurements in an anatomic volume and generating a 3D map of the conductivity directly from the obtained electrical conductivity or resistivity measurements, without segmenting the anatomic volume into tissue types. A location of the target tissue is identified within the anatomic volume, and the positions for the electrodes are determined based on the 3D map of electrical conductivity and the position of the target tissue.
    Type: Application
    Filed: December 17, 2018
    Publication date: April 25, 2019
    Applicant: Novocure Limited
    Inventors: Cornelia WENGER, Pedro Michael Cavaleiro MIRANDA, Zeev BOMZON, Noa URMAN, Eilon KIRSON, Yoram WASSERMAN, Yoram PALTI
  • Patent number: 10188851
    Abstract: When electrodes are used to impose an electric field in target tissue within an anatomic volume (e.g., to apply TTFields to treat a tumor), the position of the electrodes can be optimized by obtaining electrical conductivity measurements in an anatomic volume and generating a 3D map of the conductivity directly from the obtained electrical conductivity or resistivity measurements, without segmenting the anatomic volume into tissue types. A location of the target tissue is identified within the anatomic volume, and the positions for the electrodes are determined based on the 3D map of electrical conductivity and the position of the target tissue.
    Type: Grant
    Filed: October 27, 2016
    Date of Patent: January 29, 2019
    Assignee: NOVOCURE LIMITED
    Inventors: Cornelia Wenger, Pedro Michael Cavaleiro Miranda, Zeev Bomzon, Noa Urman, Eilon Kirson, Yoram Wasserman, Yoram Palti
  • Publication number: 20170340882
    Abstract: A system and a method for optimizing the configuration of multisite transcranial current stimulation, including providing an electric field characteristic target map on the brain's cortex, the target map including multiple cortical targets, the multiple cortical targets are localized and/or continuously varying and spatially extended, providing a weight map on the cortical surface prioritizing the important of areas in the target map for the purposes of optimization; and calculating, based on the target and weight maps, optimal currents and optimal locations for a plurality of electrodes intended for providing transcranial current stimulation to globally stimulate at once the multiple cortical targets with excitatory, inhibitory or neutral stimulation.
    Type: Application
    Filed: May 16, 2017
    Publication date: November 30, 2017
    Inventors: Giulio Ruffini, Oscar Ripolles Mateu, Alvaro Pascual-Leone, Michael D. Fox, Pedro Michael Cavaleiro Miranda
  • Patent number: 9694178
    Abstract: A system and a method for optimizing the configuration of multisite transcranial current stimulation, including providing an electric field characteristic target map on the brain's cortex, the target map including multiple cortical targets, the multiple cortical targets are localized and/or continuously varying and spatially extended, providing a weight map on the cortical surface prioritizing the important of areas in the target map for the purposes of optimization; and calculating, based on the target and weight maps, optimal currents and optimal locations for a plurality of electrodes intended for providing transcranial current stimulation to globally stimulate at once the multiple cortical targets with excitatory, inhibitory or neutral stimulation.
    Type: Grant
    Filed: October 21, 2013
    Date of Patent: July 4, 2017
    Assignees: NEUROELECTRONICS BARCELONA S.L., BETH ISRAEL DEACONESS MEDICAL CENTER
    Inventors: Giulio Ruffini, Oscar Ripolles Mateu, Alvaro Pascual-Leone, Michael D. Fox, Pedro Michael Cavaleiro Miranda
  • Publication number: 20170120041
    Abstract: When electrodes are used to impose an electric field in target tissue within an anatomic volume (e.g., to apply TTFields to treat a tumor), the position of the electrodes can be optimized by obtaining electrical conductivity measurements in an anatomic volume and generating a 3D map of the conductivity directly from the obtained electrical conductivity or resistivity measurements, without segmenting the anatomic volume into tissue types. A location of the target tissue is identified within the anatomic volume, and the positions for the electrodes are determined based on the 3D map of electrical conductivity and the position of the target tissue.
    Type: Application
    Filed: October 27, 2016
    Publication date: May 4, 2017
    Applicant: Novocure Limited
    Inventors: Cornelia WENGER, Pedro Michael Cavaleiro MIRANDA, Zeev BOMZON, Noa URMAN, Eilon KIRSON, Yoram WASSERMAN, Yoram PALTI
  • Publication number: 20150112403
    Abstract: A system and a method for optimizing the configuration of multisite transcranial current stimulation, including providing an electric field characteristic target map on the brain's cortex, the target map including multiple cortical targets, the multiple cortical targets are localized and/or continuously varying and spatially extended, providing a weight map on the cortical surface prioritizing the important of areas in the target map for the purposes of optimization; and calculating, based on the target and weight maps, optimal currents and optimal locations for a plurality of electrodes intended for providing transcranial current stimulation to globally stimulate at once the multiple cortical targets with excitatory, inhibitory or neutral stimulation.
    Type: Application
    Filed: October 21, 2013
    Publication date: April 23, 2015
    Inventors: Giulio Ruffini, Oscar Ripolles Mateu, Alvaro Pascual-Leone, Michael D. Fox, Pedro Michael Cavaleiro Miranda