Patents by Inventor Peer F. Stähler
Peer F. Stähler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10876110Abstract: The invention relates to methods and devices for preparing synthetic nucleic acids.Type: GrantFiled: March 21, 2017Date of Patent: December 29, 2020Assignee: Codex DNA, Inc.Inventors: Peer F. Staehler, Raphael Carapito, Cord F. Staehler, Mark Matzas, Jack T. Leonard, Joachim Jaeger, Markus Beier
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Publication number: 20170267999Abstract: The invention relates to methods and devices for preparing synthetic nucleic acids.Type: ApplicationFiled: March 21, 2017Publication date: September 21, 2017Inventors: Peer F. STAEHLER, Raphael CARAPITO, Cord F. STAEHLER, Mark MATZAS, Jack T. LEONARD, Joachim JAEGER, Markus BEIER
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Publication number: 20170147748Abstract: The invention relates to a method for producing polymers, in particular synthetic nucleic acid double strands of optional sequence, comprising the steps: (a) provision of a support having a surface area which contains a plurality of individual reaction areas, (b) location-resolved synthesis of nucleic acid fragments having in each case different base sequences in several of the individual reaction areas, and (c) detachment of the nucleic acid fragments from individual reaction areas.Type: ApplicationFiled: February 7, 2017Publication date: May 25, 2017Inventors: Peer F. Staehler, Cord F. Staehler, Manfred Mueller
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Patent number: 9611511Abstract: The present invention relates to single polynucleotides or sets of polynucleotides for detecting single miRNAs or sets of miRNAs for diagnosing and/or prognosing of an acute coronary syndrome in a blood sample from a human. Further, the present invention relates to means for diagnosing and/or prognosing of an acute coronary syndrome comprising said polynucleotides or sets of polynucleotides. Furthermore, the present invention relates to a method for diagnosing and/or prognosing of an acute coronary syndrome based on the determination of expression profiles of single miRNAs or sets of miRNAs representative for an acute coronary syndrome compared to a reference. In addition, the present invention relates to a kit for diagnosing and/or prognosing of an acute coronary syndrome comprising means for determining expression profiles of single miRNAs or sets of miRNAs representative for an acute coronary syndrome and at least one reference.Type: GrantFiled: April 19, 2011Date of Patent: April 4, 2017Assignee: COMPREHENSIVE BIOMARKER CENTER GMBHInventors: Andreas Keller, Peer F. Stähler, Markus Beier, Benjamin Meder, Hugo A. Katus, Wolfgang Rottbauer
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Patent number: 9568839Abstract: The invention relates to a method for producing polymers, in particular synthetic nucleic acid double strands of optional sequence, comprising the steps: (a) provision of a support having a surface area which contains a plurality of individual reaction areas, (b) location-resolved synthesis of nucleic acid fragments having in each case different base sequences in several of the individual reaction areas, and (c) detachment of the nucleic acid fragments from individual reaction areas.Type: GrantFiled: March 9, 2009Date of Patent: February 14, 2017Assignee: Synthetic Genomics, Inc.Inventors: Peer F. Stähler, Cord F. Stähler, Manfred Müller
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Publication number: 20130157883Abstract: The present invention relates to single polynucleotides or sets of polynucleotides for detecting single miRNAs or sets of miRNAs for diagnosing and/or prognosing of an acute coronary syndrome in a blood sample from a human. Further, the present invention relates to means for diagnosing and/or prognosing of an acute coronary syndrome comprising said polynucleotides or sets of polynucleotides. Furthermore, the present invention relates to a method for diagnosing and/or prognosing of an acute coronary syndrome based on the determination of expression profiles of single miRNAs or sets of miRNAs representative for an acute coronary syndrome compared to a reference. In addition, the present invention relates to a kit for diagnosing and/or prognosing of an acute coronary syndrome comprising means for determining expression profiles of single miRNAs or sets of miRNAs representative for an acute coronary syndrome and at least one reference.Type: ApplicationFiled: April 19, 2011Publication date: June 20, 2013Applicant: FEBIT HOLDING GMBHInventors: Andreas Keller, Peer F. Stähler, Markus Beier, Benjamin Meder, Hugo A. Katus, Wolfgang Rottbauer
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Publication number: 20120071327Abstract: The invention relates to a method for acquisition of genetic information, in particular for personalized medicine.Type: ApplicationFiled: December 11, 2009Publication date: March 22, 2012Applicant: FEBIT HOLDING GMBHInventors: Peer F. Staehler, Cord F. Staehler, Markus Beier, Mark S. Chee, Nadine Schracke
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Publication number: 20120045771Abstract: The invention relates to a method for isolation of target molecules from a nucleic acid population.Type: ApplicationFiled: December 11, 2009Publication date: February 23, 2012Applicant: FEBIT HOLDING GMBHInventors: Markus Beier, Peer F. Staehler, Cord F. Staehler, Daniel Summerer, Jack T. Leonard, Stephan Bau, Anthony Caruso, Nadine Schracke, Andreas Keller, Helmut Hanenberg, Olaf Eckermann
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Patent number: 7901886Abstract: The invention relates to an extraction method for isolating target molecules from a sample using a microfluidic carrier.Type: GrantFiled: November 28, 2007Date of Patent: March 8, 2011Assignee: Febit Holding GmbHInventors: Cord F. Staehler, Peer F. Staehler, Manfred Mueller
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Publication number: 20100256012Abstract: The invention relates to an extraction method for isolating target molecules from a sample with the help of a molecule library.Type: ApplicationFiled: November 24, 2008Publication date: October 7, 2010Applicant: FEBIT HOLDING GMBHInventors: Markus Beier, Stephan Bau, Daniel Summerer, Mark Matzas, Peer F. Staehler
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Patent number: 7790369Abstract: The invention relates to a method for producing polymers, in particular synthetic nucleic acid double strands of optional sequence, comprising the steps: (a) providing a support having a surface area which contains a plurality of individual reaction areas, (b) location-resolved synthesizing nucleic acid fragments each having different base sequences in several of the individual reaction areas, and (c) detaching the nucleic acid fragments from individual reaction areas.Type: GrantFiled: June 6, 2003Date of Patent: September 7, 2010Assignee: febit holding GmbHInventors: Peer F. Stähler, Cord F. Stähler, Manfred Müller
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Publication number: 20100216648Abstract: The invention relates to methods and devices for preparing synthetic nucleic acids.Type: ApplicationFiled: February 19, 2010Publication date: August 26, 2010Applicant: FEBIT HOLDING GMBHInventors: Peer F. STAEHLER, Raphael CARAPITO, Cord F. STAEHLER, Mark MATZAS, Jack T. LEONARD, Joachim JAEGER, Markus BEIER
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Patent number: 7737088Abstract: The present invention relates to arrays of biochemical and/or biofunctional elements such as nucleic acids (oligonucleotides, for example) or other biomolecules on a carrier surface and methods of producing such arrays using photoactivation of predetermined areas for synthesis using an illumination matrix that is computer-controlled to generate an exposure pattern. This exposure pattern can be adjusted and monitored by computer using a light sensor matrix, for example a CCD matrix, to allow precise, controlled illumination of specific regions and therefore attachment of array building blocks to those specific regions. The methods and compositions of the invention permit spatially resolved photochemical synthesis of polymer probes on a carrier.Type: GrantFiled: August 27, 1999Date of Patent: June 15, 2010Assignee: Febit Holding GmbHInventors: Cord F. Stähler, Peer F. Stähler, Manfred Müller, Fritz Stähler, Hans Lindner
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Patent number: 7470540Abstract: A method for preparing receptor-coated particles is described which comprises the following steps: a) providing a support body, b) conducting a liquid containing particles into or onto the support body, c) immobilizing the particles on at least one surface area of the support body, d) conducting a liquid which contains receptors or receptor building blocks for synthesizing polymeric receptors over the immobilized particles, e) coupling the receptors or receptor building blocks location—or/and time-specifically to the immobilized particles at in each case predetermined positions of the support body, f) repeating, where appropriate, the steps (d) and (e), until the desired receptors have been synthesized on the immobilized particles at the in each case predetermined positions of the support body.Type: GrantFiled: October 17, 2001Date of Patent: December 30, 2008Assignee: Febit AGInventors: Cord F. Stähler, Ramon Güimil, Matthias Scheffler, Peer F. Stähler, Anke Heidbrede
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Patent number: 7355036Abstract: The invention relates to a method for the synthesis of a nucleic acid by gradual breakdown from protected synthesis building blocks carrying two-stage protective groups.Type: GrantFiled: July 3, 2002Date of Patent: April 8, 2008Assignee: Febit AGInventors: Ramon Güimil, Matthias Scheffler, Peer F. Stähler, Barbro Beijer
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Patent number: 7320862Abstract: The invention relates to an extraction method for isolating target molecules from a sample using a microfluidic carrier.Type: GrantFiled: October 10, 2002Date of Patent: January 22, 2008Inventors: Cord F. Stähler, Peer F. Stähler, Manfred Müller
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Patent number: 7097974Abstract: A method for producing a support for determining analytes. The method comprises the steps of (a) providing a support comprising at least one channel, comprising a conduit having an intake and an outlet for passing fluid from the intake to the outlet, in the support body, (b) passing liquid with building blocks for synthesizing polymeric receptors through the channel or channels of the support body, (c) site- and/or time-specifically immobilizing the receptor building blocks in each case on predetermined positions in the channel or channels by illumination and (d) repeating steps (b) and (c) until the required receptors have been synthesized in each case on the predetermined positions.Type: GrantFiled: August 27, 1999Date of Patent: August 29, 2006Assignee: febit biotech GmbHInventors: Cord F. Stähler, Peer F. Stähler, Manfred Müller, Fritz Stähler, Hans Lindner
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Patent number: 6586211Abstract: The invention relates to a method for producing polymers, in particular synthetic nucleic acid double strands of optional sequence, comprising the steps: (a) provision of a support having a surface area which contains a plurality of individual reaction areas, (b) location-resolved synthesis of nucleic acid fragments having in each case different base sequences in several of the individual reaction areas, and (c) detachment of the nucleic acid fragments from individual reaction areas.Type: GrantFiled: July 26, 2001Date of Patent: July 1, 2003Assignee: FeBit Ferrarius Biotechnology GmbHInventors: Peer F. Stähler, Cord F. Stähler, Manfred Müller