Patents by Inventor Peilin Chen
Peilin Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11939555Abstract: A fabric care composition is provided including water; a modified carbohydrate polymer having a weight average molecular weight of <500,000 Daltons and a Kjeldahl nitrogen content corrected for ash and volatiles, TKN, of ?0.5 wt %; and a cleaning surfactant; wherein the modified carbohydrate polymer is a carbohydrate polymer functionalized with quaternary ammonium moieties; wherein the quaternary ammonium moieties on the modified carbohydrate polymer include: trimethyl ammonium moieties having formula (I) and dimethyl(alkyl) ammonium moieties having formula (II) wherein each R is independently selected from a C8-22 alkyl group.Type: GrantFiled: August 29, 2019Date of Patent: March 26, 2024Assignees: Dow Global Technologies LLC, Rohm and Haas CompanyInventors: Emmett M. Partain, III, Jan E. Shulman, Aline Migliore, Yunshen Chen, John Hayes, Asghar A. Peera, Peilin Yang, Mariann Clark, Stephen J. Donovan, Jennifer P. Todd, Cynthia Leslie
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Patent number: 11857940Abstract: The present disclosure provides a “looping amplification” method to increase the specificity of nucleic acid amplification. This increased specificity facilitates multiplexing to a much higher degree than was previously possible.Type: GrantFiled: August 10, 2021Date of Patent: January 2, 2024Assignee: Fluidigm CorporationInventor: Peilin Chen
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Patent number: 11807560Abstract: A water treatment system includes an ozone generator combined with an electrolytic chlorine generator in a compact, efficient and serviceable assembly. The system may include a modular and replaceable ozone generator, which allows a damaged or non-functional ozone generator to be quickly and efficiently replaced. In order to protect the ozone generator from damage, a fail-safe drain valve assembly may also be provided which will expel backflowing pool water before it is allowed to backflow into the ozone generator. The water treatment system may further include an insulated electrolytic chlorine generator that mitigates or eliminates current leakage for efficient operation.Type: GrantFiled: August 31, 2021Date of Patent: November 7, 2023Assignee: Intex Marketing Ltd.Inventors: Zhi Xiong Huang, Yonggui Chen, Yaw Yuan Hsu, Peilin Chen
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Patent number: 11795078Abstract: A water treatment system includes an ozone generator combined with an electrolytic chlorine generator in a compact, efficient and serviceable assembly. The system may include a modular and replaceable ozone generator, which allows a damaged or non-functional ozone generator to be quickly and efficiently replaced. In order to protect the ozone generator from damage, a fail-safe drain valve assembly may also be provided which will expel backflowing pool water before it is allowed to backflow into the ozone generator. The water treatment system may further include an insulated electrolytic chlorine generator that mitigates or eliminates current leakage for efficient operation.Type: GrantFiled: August 31, 2021Date of Patent: October 24, 2023Assignee: Intex Marketing Ltd.Inventors: Zhi Xiong Huang, Yonggui Chen, Yaw Yuan Hsu, Peilin Chen
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Patent number: 11795494Abstract: In certain embodiments, the present invention provides amplification methods in which nucleotide tag(s) and, optionally, a barcode nucleotide sequence are added to target nucleotide sequences. In other embodiments, the present invention provides a microfluidic device that includes a plurality of first input lines and a plurality of second input lines. The microfluidic device also includes a plurality of sets of first chambers and a plurality of sets of second chambers. Each set of first chambers is in fluid communication with one of the plurality of first input lines. Each set of second chambers is in fluid communication with one of the plurality of second input lines. The microfluidic device further includes a plurality of first pump elements in fluid communication with a first portion of the plurality of second input lines and a plurality of second pump elements in fluid communication with a second portion of the plurality of second input lines.Type: GrantFiled: February 3, 2021Date of Patent: October 24, 2023Assignee: FLUIDIGM CORPORATIONInventors: Andrew May, Peilin Chen, Jun Wang, Fiona Kaper, Megan Anderson
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Publication number: 20220119874Abstract: Described herein are methods useful for incorporating one or more adaptors and/or nucleotide tag(s) and/or barcode nucleotide sequence(s) one, or typically more, target nucleotide sequences. In particular embodiments, nucleic acid fragments having adaptors, e.g., suitable for use in high-throughput DNA sequencing are generated. In other embodiments, information about a reaction mixture is encoded into a reaction product. Also described herein are methods and kits useful for amplifying one or more target nucleic acids in preparation for applications such as bidirectional nucleic acid sequencing. In particular embodiments, methods of the invention entail additionally carrying out bidirectional DNA sequencing. Also described herein are methods for encoding and detecting and/or quantifying alleles by primer extension.Type: ApplicationFiled: September 20, 2021Publication date: April 21, 2022Applicant: Fluidigm CorporationInventors: Megan Anderson, Peilin Chen, Brian Fowler, Robert C. Jones, Fiona Kaper, Ronald Lebofsky, Andrew May
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Publication number: 20220088560Abstract: The present disclosure provides a “looping amplification” method to increase the specificity of nucleic acid amplification. This increased specificity facilitates multiplexing to a much higher degree than was previously possible.Type: ApplicationFiled: August 10, 2021Publication date: March 24, 2022Applicant: Fluidigm CorporationInventor: Peilin Chen
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Patent number: 11274052Abstract: A water treatment system (10) includes an ozone generator (3) combined with an electrolytic chlorine generator (4010) in a compact, efficient and serviceable assembly. The system (10) may include a modular and replaceable ozone generator (3), which allows a damaged or non-functional ozone generator (3) to be quickly and efficiently replaced. In order to protect the ozone generator (3) from damage, a fail-safe drain valve assembly may also be provided which will expel backflowing pool water before it is allowed to backflow into the ozone generator (3). The water treatment system (10) may further include an insulated electrolytic chlorine generator (4010) that mitigates or eliminates leakage current for efficient operation.Type: GrantFiled: March 31, 2018Date of Patent: March 15, 2022Assignee: INTEX MARKETING LTD.Inventors: Zhi Xiong Huang, Yonggui Chen, Yaw Yuan Hsu, Peilin Chen
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Publication number: 20210395118Abstract: A water treatment system includes an ozone generator combined with an electrolytic chlorine generator in a compact, efficient and serviceable assembly. The system may include a modular and replaceable ozone generator, which allows a damaged or non-functional ozone generator to be quickly and efficiently replaced. In order to protect the ozone generator from damage, a fail-safe drain valve assembly may also be provided which will expel backflowing pool water before it is allowed to backflow into the ozone generator. The water treatment system may further include an insulated electrolytic chlorine generator that mitigates or eliminates current leakage for efficient operation.Type: ApplicationFiled: August 31, 2021Publication date: December 23, 2021Applicant: Intex Marketing Ltd.Inventors: Zhi Xiong Huang, Yonggui Chen, Yaw Yuan Hsu, Peilin Chen
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Publication number: 20210395119Abstract: A water treatment system includes an ozone generator combined with an electrolytic chlorine generator in a compact, efficient and serviceable assembly. The system may include a modular and replaceable ozone generator, which allows a damaged or non-functional ozone generator to be quickly and efficiently replaced. In order to protect the ozone generator from damage, a fail-safe drain valve assembly may also be provided which will expel backflowing pool water before it is allowed to backflow into the ozone generator. The water treatment system may further include an insulated electrolytic chlorine generator that mitigates or eliminates current leakage for efficient operation.Type: ApplicationFiled: August 31, 2021Publication date: December 23, 2021Applicant: Intex Marketing Ltd.Inventors: Zhi Xiong Huang, Yonggui Chen, Yaw Yuan Hsu, Peilin Chen
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Publication number: 20210324446Abstract: In certain embodiments, the present invention provides amplification methods in which nucleotide tag(s) and, optionally, a barcode nucleotide sequence are added to target nucleotide sequences. In other embodiments, the present invention provides a microfluidic device that includes a plurality of first input lines and a plurality of second input lines. The microfluidic device also includes a plurality of sets of first chambers and a plurality of sets of second chambers. Each set of first chambers is in fluid communication with one of the plurality of first input lines. Each set of second chambers is in fluid communication with one of the plurality of second input lines. The microfluidic device further includes a plurality of first pump elements in fluid communication with a first portion of the plurality of second input lines and a plurality of second pump elements in fluid communication with a second portion of the plurality of second input lines.Type: ApplicationFiled: February 3, 2021Publication date: October 21, 2021Applicant: Fluidigm CorporationInventors: Andrew May, Peilin Chen, Jun Wang, Fiona Kaper, Megan Anderson
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Patent number: 11117113Abstract: The present disclosure provides a “looping amplification” method to increase the specificity of nucleic acid amplification. This increased specificity facilitates multiplexing to a much higher degree than was previously possible.Type: GrantFiled: December 16, 2016Date of Patent: September 14, 2021Assignee: FLUIDIGM CORPORATIONInventor: Peilin Chen
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Patent number: 11078476Abstract: This invention provides a technology for isolating nucleic acids from wax-embedded samples that is superior to the current state of the art. Standard protocols with this objective typically comprise dissolving the wax-embedded sample in an organic solvent, extracting nucleic acids from the organic solvent into an aqueous buffer, and isolating the nucleic acids from the aqueous buffer. The technology described here includes using hexadecane as the solvent to dissolve the sample, precipitating and washing the extracted nucleic acids, and dissolving the nucleic acids in a lysis buffer that includes NP40 and SDS. By implementing the reagents and techniques described in this disclosure, the user can obtain a product that has better yield, less degradation, and contains more unique mRNA transcripts for subsequent sequencing and analysis.Type: GrantFiled: August 20, 2018Date of Patent: August 3, 2021Assignee: FLUIDIGM CORPORATIONInventors: Jian Qin, Peilin Chen, Ramesh Ramakrishnan
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Publication number: 20210087085Abstract: A water treatment system (10) includes an ozone generator (3) combined with an electrolytic chlorine generator (4010) in a compact, efficient and serviceable assembly. The system (10) may include a modular and replaceable ozone generator (3), which allows a damaged or non-functional ozone generator (3) to be quickly and efficiently replaced. In order to protect the ozone generator (3) from damage, a fail-safe drain valve assembly may also be provided which will expel backflowing pool water before it is allowed to backflow into the ozone generator (3). The water treatment system (10) may further include an insulated electrolytic chlorine generator (4010) that mitigates or eliminates leakage current for efficient operation.Type: ApplicationFiled: March 31, 2018Publication date: March 25, 2021Applicant: Intex Marketing Ltd.Inventors: Zhi Xiong Huang, Yonggui Chen, Yaw Yuan Hsu, Peilin Chen
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Publication number: 20200102594Abstract: In certain embodiments, the present invention provides amplification methods in which nucleotide tag(s) and, optionally, a barcode nucleotide sequence are added to target nucleotide sequences. In other embodiments, the present invention provides a microfluidic device that includes a plurality of first input lines and a plurality of second input lines. The microfluidic device also includes a plurality of sets of first chambers and a plurality of sets of second chambers. Each set of first chambers is in fluid communication with one of the plurality of first input lines. Each set of second chambers is in fluid communication with one of the plurality of second input lines. The microfluidic device further includes a plurality of first pump elements in fluid communication with a first portion of the plurality of second input lines and a plurality of second pump elements in fluid communication with a second portion of the plurality of second input lines.Type: ApplicationFiled: May 16, 2019Publication date: April 2, 2020Inventors: Andrew May, Peilin Chen, Jun Wang, Fiona Kaper, Megan Anderson
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Patent number: 10501786Abstract: Described herein are methods useful for incorporating one or more adaptors and/or nucleotide tag(s) and/or barcode nucleotide sequence(s) one, or typically more, target nucleotide sequences. In particular embodiments, nucleic acid fragments having adaptors, e.g., suitable for use in high-throughput DNA sequencing are generated. In other embodiments, information about a reaction mixture is encoded into a reaction product. Also described herein are methods and kits useful for amplifying one or more target nucleic acids in preparation for applications such as bidirectional nucleic acid sequencing. In particular embodiments, methods of the invention entail additionally carrying out bidirectional DNA sequencing. Also described herein are methods for encoding and detecting and/or quantifying alleles by primer extension.Type: GrantFiled: May 28, 2015Date of Patent: December 10, 2019Assignee: Fluidigm CorporationInventors: Megan Anderson, Peilin Chen, Brian Fowler, Robert C. Jones, Fiona Kaper, Ronald Lebofsky, Andrew May
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Publication number: 20190256881Abstract: The present invention provides reagents, kits, and methods for single-cell whole genome amplification using Phi 29 DNA polymerase.Type: ApplicationFiled: January 24, 2019Publication date: August 22, 2019Inventors: Peilin Chen, Jing Wang, Andrew May
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Patent number: 10344318Abstract: In certain embodiments, the present invention provides amplification methods in which nucleotide tag(s) and, optionally, a barcode nucleotide sequence are added to target nucleotide sequences. In other embodiments, the present invention provides a microfluidic device that includes a plurality of first input lines and a plurality of second input lines. The microfluidic device also includes a plurality of sets of first chambers and a plurality of sets of second chambers. Each set of first chambers is in fluid communication with one of the plurality of first input lines. Each set of second chambers is in fluid communication with one of the plurality of second input lines. The microfluidic device further includes a plurality of first pump elements in fluid communication with a first portion of the plurality of second input lines and a plurality of second pump elements in fluid communication with a second portion of the plurality of second input lines.Type: GrantFiled: May 9, 2017Date of Patent: July 9, 2019Assignee: FLUIDIGM CORPORATIONInventors: Andrew May, Peilin Chen, Jun Wang, Fiona Kaper, Megan Anderson
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Patent number: D884031Type: GrantFiled: July 16, 2018Date of Patent: May 12, 2020Assignee: Intex Marketing Ltd.Inventors: Zhi Xiong Huang, Yonggui Chen, Peilin Chen, Yaw Yuan Hsu, James Sener, Christopher David Hageman, Scott Herman Smith
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Patent number: D884032Type: GrantFiled: July 16, 2018Date of Patent: May 12, 2020Assignee: Intex Marketing Ltd.Inventors: Zhi Xiong Huang, Yonggui Chen, Peilin Chen, Yaw Yuan Hsu, James Sener, Christopher David Hageman, Scott Herman Smith