Patents by Inventor Pengchin Chen

Pengchin Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for Fragmentation and Labeling of Nucleic Acids
    Publication number: 20140065692
    Abstract: The invention provides methods, compositions, and kits for fragmentation and labeling of nucleic acids. More particularly, the invention relates to methods for fragmentation of nucleic acids to produce fragments with 3? end hydroxyl groups within a desired size range. In methods of the invention, nucleic acids are fragmented at abasic sites to produce fragments with blocked 3? ends. The 3? ends are unblocked to produce polynucleotide fragments with hydroxyl groups at their 3? ends. Methods, kits, and compositions for carrying out fragmentation of a polynucleotide template in a single reaction mixture to yield fragments with 3?-hydroxl ends within the desired size range are disclosed.
    Type: Application
    Filed: August 28, 2013
    Publication date: March 6, 2014
    Inventors: Nurith KURN, Pengchin Chen
  • Methods for fragmentation and labeling of nucleic acids
    Patent number: 8551709
    Abstract: The invention provides methods, compositions, and kits for fragmentation and labeling of nucleic acids. More particularly, the invention relates to methods for fragmentation of nucleic acids to produce fragments with 3? end hydroxyl groups within a desired size range. In methods of the invention, nucleic acids are fragmented at abasic sites to produce fragments with blocked 3? ends. The 3? ends are unblocked to produce polynucleotide fragments with hydroxyl groups at their 3? ends. Methods, kits, and compositions for carrying out fragmentation of a polynucleotide template in a single reaction mixture to yield fragments with 3?-hydroxyl ends within the desired size range are disclosed.
    Type: Grant
    Filed: March 2, 2012
    Date of Patent: October 8, 2013
    Assignee: NuGEN Technologies, Inc.
    Inventors: Nurith Kurn, Pengchin Chen
  • METHODS FOR FRAGMENTATION AND LABELING OF NUCLEIC ACIDS
    Publication number: 20120220483
    Abstract: The invention provides methods, compositions, and kits for fragmentation and labeling of nucleic acids. More particularly, the invention relates to methods for fragmentation of nucleic acids to produce fragments with 3? end hydroxyl groups within a desired size range. In methods of the invention, nucleic acids are fragmented at abasic sites to produce fragments with blocked 3? ends. The 3? ends are unblocked to produce polynucleotide fragments with hydroxyl groups at their 3? ends. Methods, kits, and compositions for carrying out fragmentation of a polynucleotide template in a single reaction mixture to yield fragments with 3?-hydroxyl ends within the desired size range are disclosed.
    Type: Application
    Filed: March 2, 2012
    Publication date: August 30, 2012
    Applicant: NuGen Technologies, Inc.
    Inventors: Nurith KURN, Pengchin Chen
  • METHODS FOR FRAGMENTATION AND LABELING OF NUCLEIC ACIDS
    Publication number: 20100022403
    Abstract: The invention provides methods, compositions, and kits for fragmentation and labeling of nucleic acids. More particularly, the invention relates to methods for fragmentation of nucleic acids to produce fragments with 3? end hydroxyl groups within a desired size range. In methods of the invention, nucleic acids are fragmented at abasic sites to produce fragments with blocked 3? ends. The 3? ends are unblocked to produce polynucleotide fragments with hydroxyl groups at their 3? ends. Methods, kits, and compositions for carrying out fragmentation of a polynucleotide template in a single reaction mixture to yield fragments with 3?-hydroxyl ends within the desired size range are disclosed.
    Type: Application
    Filed: July 2, 2007
    Publication date: January 28, 2010
    Inventors: Nurith Kurn, Pengchin Chen