Patents by Inventor Pengfei Dong

Pengfei Dong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240169524
    Abstract: The present disclosure, in some embodiments, relates to a method of determining a stent effectiveness. The method includes accessing a pre-stent intravascular image of a blood vessel of a patient. One or more pre-stent label volumes of the blood vessel are determined and one or more treatment variables associated with the pre-stent intravascular image are determined. One or more FEM-mimic simulations are generated by applying a first deep learning model to the one or more pre-stent label volumes and the one or more treatment variables. The one or more FEM-mimic simulations are used to determine a stent effectiveness metric.
    Type: Application
    Filed: June 12, 2023
    Publication date: May 23, 2024
    Inventors: David L. Wilson, Yazan Gharaibeh, Juhwan Lee, Linxia Gu, Pengfei Dong, Sadeer Al-Kindi, Hiram Bezerra
  • Publication number: 20240158480
    Abstract: Disclosed in the present invention is an anti-Nipah virus monoclonal antibody having neutralization activity. The antibody consists of a monkey-derived variable region and a human constant region, and both light and heavy chains of the monkey-derived variable region have unique CDR regions. The antibody provided by the present invention has an excellent antigen binding capability, and has good binding activity with Bangladesh Nipah virus and Malaysia Nipah virus glycoprotein G. The antibody can effectively neutralize the Nipahpseudovirus. Moreover, the neutralization activity of the antibody is enhanced as the concentration of the antibody increases, and nearly 100% neutralization of the Nipahpseudovirus can be achieved at a concentration of 1 ?g/mL. Also disclosed in the present invention is an application of the monoclonal antibody against the Nipah virus glycoprotein G in preparation of a Nipah virus treatment drug.
    Type: Application
    Filed: June 26, 2021
    Publication date: May 16, 2024
    Applicant: ACADEMY OF MILITARY MEDICAL SCIENCE, PLA
    Inventors: Wei Chen, Changming Yu, Yujiao Liu, Pengfei Fan, Guanying Zhang, Yaohui Li, Jianmin Li, Xiangyang Chi, Meng Hao, Ting Fang, Yunzhu Dong, Xiaohong Song, Yi Chen, Shuling Liu
  • Publication number: 20240077489
    Abstract: Styryl compounds useful for preparing biological detections probes, and the use of the Styryl compounds for the detection, discrimination and quantification of biological targets.
    Type: Application
    Filed: October 16, 2023
    Publication date: March 7, 2024
    Inventors: Zhenjun Diwu, Zhen Luo, Jixiang Liu, Pengfei Dong
  • Patent number: 11821901
    Abstract: Styryl compounds useful for preparing biological detections probes, and the use of the Styryl compounds for the detection, discrimination and quantification of biological targets.
    Type: Grant
    Filed: August 15, 2020
    Date of Patent: November 21, 2023
    Assignee: AAT Bioquest, Inc.
    Inventors: Zhenjun Diwu, Zhen Luo, Jixiang Liu, Pengfei Dong
  • Publication number: 20230362317
    Abstract: The present application is applicable to the field of video processing, and provides a method for generating a rotation direction of a gyroscope, a method for achieving a bullet time photographing effect, a computer readable storage medium, a computer device, and a camera.
    Type: Application
    Filed: September 24, 2021
    Publication date: November 9, 2023
    Inventors: PENGFEI DONG, CONG CHEN
  • Publication number: 20230223152
    Abstract: The present disclosure, in some embodiments, relates to a method of predicting stent expansion. The method includes accessing a pre-stent intravascular image of a blood vessel of a patient and segmenting the pre-stent intravascular image to identify a lumen and a calcification lesion. A plurality of features are extracted from one or more of the lumen and the calcification lesion. A regression model is applied to one or more of the plurality of features to determine a minimum stent expansion metric (mSEM). The mSEM indicating how much a stent will expand after implantation. The mSEM is used to generate a classification of the blood vessel as an under-expanded area or a well-expanded area.
    Type: Application
    Filed: January 5, 2023
    Publication date: July 13, 2023
    Inventors: David L. Wilson, Yazan Gharaibeh, Juhwan Lee, Sadeer Al-Kindi, Vladislav N. Zimin, Linxia Gu, Pengfei Dong, Hiram Bezerra
  • Patent number: 11237170
    Abstract: Styryl compounds useful for preparing biological detections probes, and the use of the Styryl compounds for the detection, discrimination and quantification of biological targets.
    Type: Grant
    Filed: December 4, 2018
    Date of Patent: February 1, 2022
    Assignee: AAT BIOQUEST, INC.
    Inventors: Zhenjun Diwu, Zhen Luo, Jixiang Liu, Pengfei Dong
  • Publication number: 20200378975
    Abstract: Styryl compounds useful for preparing biological detections probes, and the use of the Styryl compounds for the detection, discrimination and quantification of biological targets.
    Type: Application
    Filed: August 15, 2020
    Publication date: December 3, 2020
    Applicant: AAT BIOQUEST, INC.
    Inventors: Zhenjun Diwu, Zhen Luo, Jixiang Liu, Pengfei Dong
  • Publication number: 20200174006
    Abstract: Styryl compounds useful for preparing biological detections probes, and the use of the Styryl compounds for the detection, discrimination and quantification of biological targets.
    Type: Application
    Filed: December 4, 2018
    Publication date: June 4, 2020
    Inventors: Zhenjun Diwu, Zhen Luo, Jixiang Liu, Pengfei Dong