Abstract: A camera system comprises: a main control chip, wherein the main control chip includes at least one main control unit; at least one group of cameras, wherein each camera in each group of cameras includes an image acquisition control chip; and at least one pair of bidirectional differential data lines, wherein each pair of bidirectional differential data lines is connected to a single main control unit and all image acquisition control chips in a single group of cameras.

Abstract: This application discloses a configuration method for a network coding function and a related apparatus. The network coding function is implemented on a first access network device. Information needed for a terminal device to perform network coding and/or network decoding is configured by the first access network device, to enable network coding and decoding between the first access network device and the terminal device to be possible. After the network coding function is introduced to an access layer, both latency performance and spectral efficiency performance are considered by transmitting an encoded packet. To be specific, the first access network device may flexibly adjust a quantity of sent encoded packets based on quality of an air interface link, to ensure that the terminal device can successfully perform decoding, reducing a data transmission latency while ensuring service transmission reliability.

Abstract: A cordycepin-based derived compound with an anti-tumor effect, and a structure of the compound is as shown in formula I; a cordycepin derivative and a pharmaceutical composition thereof provided by the invention have a good anti-tumor proliferation effect; compared with a parent drug, the cordycepin derivative has better affinity to cell membranes, so that a half-life period of in-vivo metabolism of the drug is longer, and in-vivo remaining time of the drug is longer; compared with other nucleoside anti-tumor drugs, the cordycepin derivative and the pharmaceutical composition thereof provided by the invention have wider types and action ranges of tumors, have excellent inhibition effects on a gastric cancer, a pancreatic cancer, a liver cancer, a small cell lung cancer, a colorectal cancer, melanoma, an ovarian cancer and the like, and have lower side effects and better curative effects.

Abstract: A natural gas separation and purification and mercury collection system for oil and gas wells includes a cyclone separator, a condensation purification and separation mechanism, pressure buffer mechanisms, mercury collection and separation mechanisms, and natural gas storage tanks. An inlet end of the cyclone separator is communicated with an external gas source through a pressure buffer mechanism, and an outlet end of the cyclone separator is communicated with the condensation purification and separation mechanism through a pressure buffer mechanism. The condensation purification and separation mechanism is communicated with the mercury collection and separation mechanism through a pressure buffer mechanism. The mercury collection and separation mechanism is communicated with the natural gas storage tank through a guide tube. A method of use of the natural gas separation and purification and mercury collection system includes gas collection, gas purification, mercury separation, and mercury analysis.

Abstract: A method is provided that a transmitting end generates a data segment, where the data segment includes header information and data parts of a plurality of CBs that are obtained by dividing a TB, there is a position mapping relationship between the data parts of the plurality of CBs and N sub-PDUs included in a MAC PDU, and the header information of each CB indicates a position mapping relationship between the CB and a sub-PDU corresponding to the CB. The transmitting end sends the TB that carries the data segment. Therefore, at a receiving end, if a CRC error occurs on the TB, the receiving end obtains a position of each CB and performs a CRC decision by using a CB as a granularity, to obtain a correct CB. Thereby performance of a wireless communication system is improved.

Abstract: The present applications discloses an NLS-optimized SpCas9-based prime editor that improves genome editing efficiency exemplified by endogenous loci in cultured cell lines. Using this genome modification system, tumor formation can be initiated through somatic cell editing in the adult mouse. Furthermore, a dual adeno-associated vims (AAVs) is utilized for the delivery of a split-intein prime editor for correction of in vivo pathogenic mutations.

Abstract: RNA-guided programmable cytosine and adenine base editors are a powerful class of genome editing tool for the introduction of localized base transitions without generating a double-stranded DNA break. Base editors (BE) have an optimal window of activity relative to the PAM recognized by the Cas9 enzyme and these constructs are strand selective. Here we demonstrate that fusion of a programmable DNA-binding domain (pDBD) or another Cas9 orthologue to spCas9-BE, we can produce an RNA-programmable Cas9-BE-pDBD chimera or Cas9-BE-Cas9 chimeras with dramatically improved activities and increased targeting range. Cas9-pDBD or Cas9-Cas9 fusion base editors display an expanded targeting repertoire and achieve highly specific genome editing, which can be tailored to achieve extremely precise genome editing at nearly any genomic locus.

Abstract: The present invention is related to the field of gene editing. In particular, the gene editing is directed toward single nucleotide base editing. For example, such single nucleotide base editing results in a conversion of a OG base pair to a T*A base pair. The high accuracy and precision of the presently disclosed single nucleotide base gene editor is accomplished by an NmeCas9 nuclease that is fused to a nucleotide deaminase protein. The compact nature of the NmeCas9 coupled with a larger number of compatible protospacer adjacent motifs provide the Cas9 fusion constructs contemplated herein to have a gene editing window that can edit sites that are not targetable by other conventional SpyCas9 base editor platforms.

Abstract: A binocular image-based model training method and apparatus, and a data processing device are provided. An image matching model includes a teacher model and a student model. In the method, two groups of sample images acquired at different time points by a binocular image acquisition apparatus are first obtained; then, for any two sample images in the two groups of sample images, optical flow estimation is performed according to a preset geometric constraint between the two sample images by means of the teacher model, so as to obtain a more accurate high-confidence optical flow estimation result, the preset geometric constraint being a binocular image-based geometric constraint; and finally, machine learning training of image element matching is performed on the student model by using the two sample image, with the high-confidence optical flow estimation result taken as labeling information.

Abstract: Provided are a monocular image-based model training method and apparatus, and a data processing device. The method includes: first obtaining a first training image and a second training image acquired at different time points by a monocular image acquisition apparatus; then obtaining a first optical flow prediction result from the first training image to the second training image according to a photometric loss between the first training image and the second training image; and taking the first optical flow prediction result as an agent label, and performing optical flow prediction training by using the first training image and the second training image.

Abstract: Provided herein are synthetic nucleic acids that encode a CRISPR enzyme fused to a series of nuclear localization signal sequences for the use of altering expression of a gene in a cell. Further provided herein are methods for altering gene expression in a cell comprising introducing the synthetic nucleic acids and a guide RNA, or a polypeptide and a guide RNA into a cell. In certain embodiments the cell is a quiescent cell, for example, a hematopoietic stem cell.

Abstract: Provided herein are methods and compositions for increasing fetal hemoglobin levels in a cell by disrupting BCL11A expression at the genomic level. Also provided herein are methods and compositions relating to the treatment of hemoglobinopathies by reinduction of fetal hemoglobin levels.

Abstract: The present disclosure discloses a voice remote controller and a power supplying method thereof. The voice remote controller comprises: a noise gathering module for gathering ambient noise at the periphery of the voice remote controller by using a sound aperture array; a sound-electricity converting module for converting the ambient noise gathered by the noise gathering module into an electrical signal; and an energy storing module for storing the electrical signal converted by the sound-electricity converting module as electric energy and supplying power to the voice remote controller. According to the present disclosure, ambient noise is gathered by a sound aperture array and converted into electricity used as the working energy, thereby avoiding battery replacing or frequent charging. When a voice function of a voice remote controller is turned off, all of the gathered ambient noise is converted into electricity, thereby improving the energy utilization rate.

Abstract: The present disclosure discloses a voice remote controller and a power supplying method thereof. The voice remote controller comprises: a noise gathering module for gathering ambient noise at the periphery of the voice remote controller by using a sound aperture array; a sound-electricity converting module for converting the ambient noise gathered by the noise gathering module into an electrical signal; and an energy storing module for storing the electrical signal converted by the sound-electricity converting module as electric energy and supplying power to the voice remote controller. According to the present disclosure, ambient noise is gathered by a sound aperture array and converted into electricity used as the working energy, thereby avoiding battery replacing or frequent charging. When a voice function of a voice remote controller is turned off, all of the gathered ambient noise is converted into electricity, thereby improving the energy utilization rate.