Patents by Inventor Per Olaf Huusfeldt

Per Olaf Huusfeldt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Derivatives of GLP-1 analogs
    Patent number: 8097698
    Abstract: The present invention relates to a pharmaceutical composition comprising a GLP-1 derivative having a lipophilic substituent; and a surfactant.
    Type: Grant
    Filed: November 26, 2007
    Date of Patent: January 17, 2012
    Assignee: Novo Nordisk A/S
    Inventors: Liselotte Bjerre Knudsen, Per Olaf Huusfeldt, Per Franklin Nielsen, Niels C. Kaarsholm, Helle Birk Olsen, Soren Erik Bjorn, Freddy Zimmerdahl Pedersen, Kjeld Madsen
  • GLP-1 Derivatives II
    Publication number: 20110053839
    Abstract: The present invention relates to a derivative of GLP-1(7-C), wherein C is 35 or 36 which derivative has just one lipophilic substituent which is attached to the C-terminal amino acid residue.
    Type: Application
    Filed: August 23, 2010
    Publication date: March 3, 2011
    Applicant: NOVO NORDISK A/S
    Inventors: LISELOTTE BJERRE KNUDSEN, PER OLAF HUUSFELDT, PER FRANKLIN NIELSEN, KJELD MADSEN
  • Derivatives Of GLP-1 Analogs
    Publication number: 20090176700
    Abstract: The present invention relates to a pharmaceutical composition comprising a GLP-1 derivative having a lipophilic substituent; and a surfactant.
    Type: Application
    Filed: November 26, 2007
    Publication date: July 9, 2009
    Applicant: Novo Nordisk A/S
    Inventors: Liselotte Bjerre Knudsen, Per Olaf Huusfeldt, Per Franklin Nielsen, Niels C. Kaarsholm, Helle Birk Olsen, Soren Erik Bjorn, Freddy Zimmerdahl Pedersen, Kjeld Madsen
  • GLP-1 derivatives II
    Publication number: 20080103097
    Abstract: The present invention relates to a derivative of GLP-1(7-C), wherein C is 35 or 36 which derivative has just one lipophilic substituent which is attached to the C-terminal amino acid residue.
    Type: Application
    Filed: April 26, 2007
    Publication date: May 1, 2008
    Applicant: Novo Nordisk A/S
    Inventors: Liselotte Bjerre Knudsen, Per Olaf Huusfeldt, Per Franklin Nielsen, Kjeld Madsen
  • Derivatives of GLP-1 analogs
    Patent number: 7235627
    Abstract: The present invention relates to a pharmaceutical composition comprising a GLP-1 derivative having a lipophilic substituent; and a surfactant.
    Type: Grant
    Filed: August 19, 2002
    Date of Patent: June 26, 2007
    Assignee: Novo Nordisk A/S
    Inventors: Liselotte Bjerre Knudson, Per Olaf Huusfeldt, Per Franklin Nielsen
  • Extendin derivatives
    Patent number: 7226990
    Abstract: The present invention relates to novel derivatives of exendin-4 or exendin-4 fragments, wherein the derivatives have a lipophilic substituent attached, optionally via a spacer, to an amino acid residue, which is not the N-terminal or C-terminal amino acid residue of the derivative.
    Type: Grant
    Filed: June 21, 2001
    Date of Patent: June 5, 2007
    Assignee: Novo Nordisk A/S
    Inventors: Liselotte Bjerre Knudsen, Per Olaf Huusfeldt, Per Franklin Nielsen, Kjeld Madsen
  • GLP-2 derivatives
    Publication number: 20040127418
    Abstract: Analogs of GLP-2, pharmaceutical compositions comprising GLP-2 analogs, and methods of treating diseases and disorders comprising administering such analogs or compositions are provided.
    Type: Application
    Filed: December 8, 2003
    Publication date: July 1, 2004
    Inventors: Liselotte Bjerre Knudsen, Per Olaf Huusfeldt, Per Franklin Nielsen, Niels C. Kaarsholm, Helle Birk Olsen, Lars Thim, Soren Erik Bjorn
  • Derivatives of GLP-1 analogs
    Publication number: 20030199672
    Abstract: The present invention relates to a pharmaceutical composition comprising a GLP-1 derivative having a lipophilic substituent; and a surfactant.
    Type: Application
    Filed: August 19, 2002
    Publication date: October 23, 2003
    Inventors: Liselotte Bjerre Knudsen, Per Olaf Huusfeldt, Per Franklin Nielsen, Niels C. Kaarsholm, Helle Birk Olsen, Soren Erik Bjorn, Freddy Zimmerdahl Pedersen, Kjeld Madsen
  • Derivatives of GLP-1 analogs
    Patent number: 6458924
    Abstract: The present invention relates to a pharmaceutical composition comprising a GLP-1 derivative having a lipophilic substituent; and a surfactant.
    Type: Grant
    Filed: September 16, 1999
    Date of Patent: October 1, 2002
    Assignee: Novo Nordisk A/S
    Inventors: Liselotte Bjerre Knudsen, Per Olaf Huusfeldt, Per Franklin Nielsen
  • GLP-2 derivatives
    Publication number: 20020025933
    Abstract: The present invention relates to derivatives of hGLP-2 and analogues and/or fragments thereof having a lipophilic substituent have interesting pharmacological properties, in particular they have a more protracted profile of action than the parent peptides.
    Type: Application
    Filed: July 18, 2001
    Publication date: February 28, 2002
    Inventors: Liselotte Bjerre Knudsen, Per Olaf Huusfeldt, Per Franklin Nielsen, Niels C. Kaarsholm, Helle Birk Olsen, Lars Thim, Soren Erik Bjorn
  • Extendin derivatives
    Publication number: 20010047084
    Abstract: The present invention relates to a derivative of GLP-1 (7-C), wherein C is 35 or 36 which derivative has just one lipophilic substituent which is attached to the C-terminal amino acid residue.
    Type: Application
    Filed: June 21, 2001
    Publication date: November 29, 2001
    Inventors: Liselotte Bjerre Knudsen, Per Olaf Huusfeldt, Per Franklin Nielsen, Kjeld Madsen
  • DERIVATIVES OF GLP-1 ANALOGS
    Publication number: 20010011071
    Abstract: The present invention relates to a pharmaceutical composition comprising a GLP-1 derivative having a lipophilic substituent; and a surfactant.
    Type: Application
    Filed: September 16, 1999
    Publication date: August 2, 2001
    Inventors: LISELOTTE BJERRE KNUDSEN, PER OLAF HUUSFELDT, PER FRANKLIN NIELSEN, NIELS C. KAARSHOLM, HELLE BIRK OLSEN, SOREN ERIK BJORN, FREDDY ZIMMERDAHL PEDERSEN, KJELD MADSEN
  • Derivatives of GLP-1 analogs
    Patent number: 6268343
    Abstract: The present invention relates to GLP-1 derivatives having a lipophilic substituent, pharmaceutical compositions comprising same, and methods of making an using same. The GLP-1 derivatives of the present invention have a protracted profile of action.
    Type: Grant
    Filed: February 26, 1999
    Date of Patent: July 31, 2001
    Assignee: Novo Nordisk A/S
    Inventors: Liselotte Bjerre Knudsen, Per Olaf Huusfeldt, Per Franklin Nielsen, Niels C. Kaarsholm, Helle Birk Olsen, Søren Erik Bjørn, Freddy Zimmerdahl Pedersen, Kjeld Madsen
  • Carbazolypiperines as GABA uptake inhibitors
    Patent number: 6071932
    Abstract: A compound of formula (I). ##STR1## The present invention relates to thereutically active carbazole derivatives, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in treating a central nervous system ailment related to the inhibition of GABA uptake via the GAT-4 subtype carrier.
    Type: Grant
    Filed: October 21, 1997
    Date of Patent: June 6, 2000
    Assignee: British Technology Group Intercorporate Licensing Limited
    Inventors: Jesper Lau, Jane Marie Lundbeck, Birgitte Soekilde, Per Olaf Huusfeldt
  • Heterocyclic chemistry
    Patent number: 5834482
    Abstract: A compound of formula (I). The present invention relates to therapeutically active .beta.-carboline derivatives, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in treating a central nervous system ailment related to the inhibition of GABA uptake via the GAT-4 subtype carrier.
    Type: Grant
    Filed: October 21, 1997
    Date of Patent: November 10, 1998
    Assignee: Novo Nordisk A/S
    Inventors: Jane Marie Lundbeck, Birgitte Soekilde, Per Olaf Huusfeldt