Patents by Inventor Per Uselius
Per Uselius has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20180229152Abstract: A parallel assembly (2; 11; 51) of chromatography column modules (3a,b,c; 13a,b,c; 53a,b,c, 90a, b) connected in a rigid housing (21; 61), the assembly having one common assembly inlet (15; 55) and one common assembly outlet (17; 57), each column module comprising a bed space (29) filled with chromatography medium and each column module comprises integrated fluid conduits which when the column module is connected with other column modules in the rigid housing are adapted to connect the bed space (29) of the column module with the assembly inlet (15; 55) and the assembly outlet (17; 57), wherein the total length and/or volume of the fluid conduit from the assembly inlet to one bed space together with the length and/or volume of the fluid conduit from the same bed space to the assembly outlet is substantially the same for all bed spaces and modules installed in the parallel assembly.Type: ApplicationFiled: April 16, 2018Publication date: August 16, 2018Applicant: GE Healthcare BioProcess R&D ABInventors: Klaus Gebauer, Manoj Kumar Ramakrishna, Daniel Salomonsson, Per Uselius
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Patent number: 9943781Abstract: A parallel assembly (2; 11; 51) of chromatography column modules (3a,b,c; 13a,b,c; 53a,b,c, 90a, b) connected in a rigid housing (21; 61), the assembly having one common assembly inlet (15; 55) and one common assembly outlet (17; 57), each column module comprising a bed space (29) filled with chromatography medium and each column module comprises integrated fluid conduits which when the column module is connected with other column modules in the rigid housing are adapted to connect the bed space (29) of the column module with the assembly inlet (15; 55) and the assembly outlet (17; 57), wherein the total length and/or volume of the fluid conduit from the assembly inlet to one bed space together with the length and/or volume of the fluid conduit from the same bed space to the assembly outlet is substantially the same for all bed spaces and modules installed in the parallel assembly.Type: GrantFiled: June 1, 2011Date of Patent: April 17, 2018Assignee: GE HEALTHCARE BIOPROCESS R&D ABInventors: Klaus Gebauer, Manoj Kumar Ramakrishna, Daniel Salomonsson, Per Uselius
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Patent number: 9155979Abstract: A method for performing maintenance on a chromatography column (1; 41) comprising the steps of: a) when maintenance is required, detaching a detachable joint (7; 63) between a bottom plate (5; 53) of the chromatography column and a stand (3; 43) on which the chromatography column is provided; b) attaching an adaptor (15; 59) provided in the chromatography system to any part of the chromatography column (1; 41) making it possible to lift the bottom plate (5; 53) from the stand (3; 43) with the adaptor (15; 59); and c) raising the adaptor (15; 59) and thereby also the bottom plate (5; 53) such that maintenance can be performed under the bottom plate (5; 53).Type: GrantFiled: January 20, 2014Date of Patent: October 13, 2015Assignee: GE Healthcare Bio-Sciences ABInventors: Manoj Kumar Ramakrishna, Daniel Salomonsson, Per Uselius
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Patent number: 8778188Abstract: A chromatography column having a longitudinal axis and comprising a column wall with a first end and a second end, a first end plate assembly removably connectable to said first end of the column wall, a second end plate assembly removably connectable to said second end of the column wall, wherein said first end plate assembly, said column wall and said second end plate assembly are arranged along the longitudinal axis of the column wherein the column wall, and/or first end plate assembly and/or second end plate assembly is/are rotatable about an axis of rotation wherein said axis of rotation is parallel to the longitudinal axis of said column and positioned outside the column.Type: GrantFiled: October 14, 2008Date of Patent: July 15, 2014Assignee: GE Healthcare Bio-Sciences ABInventors: Per Uselius, Mats Olsson, Sven Wounder, Jerker Persson
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Publication number: 20140131267Abstract: A method for conducting maintenance on a chromatography column (1; 51), said column comprising a column tube (32), a top end cell (20) and a bottom end cell (26), where during chromatography said column tube (32) is secured between said top end cell (20) and said bottom end cell (26). Said method comprises the step of rotating at least the top end cell (20) 180 degrees around a horizontal axis before maintenance is conducted to the top end cell (20).Type: ApplicationFiled: January 21, 2014Publication date: May 15, 2014Applicant: GE HEALTHCARE BIO-SCIENCES ABInventors: PER USELIUS, KYRIL DAMBULEFF, JOHN DAVIS
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Publication number: 20140131266Abstract: A method for performing maintenance on a chromatography column (1; 41) comprising the steps of: a) when maintenance is required, detaching a detachable joint (7; 63) between a bottom plate (5; 53) of the chromatography column and a stand (3; 43) on which the chromatography column is provided; b) attaching an adaptor (15; 59) provided in the chromatography system to any part of the chromatography column (1; 41) making it possible to lift the bottom plate (5; 53) from the stand (3; 43) with the adaptor (15; 59); and c) raising the adaptor (15; 59) and thereby also the bottom plate (5; 53) such that maintenance can be performed under the bottom plate (5; 53).Type: ApplicationFiled: January 20, 2014Publication date: May 15, 2014Applicant: GE HEALTHCARE BIO-SCIENCES ABInventors: MANOJ KUMAR RAMAKRISHNA, DANIEL SALOMONSSON, PER USELIUS
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Patent number: 8668829Abstract: A method for performing maintenance on a chromatography column (1; 41) comprising the steps of: a) when maintenance is required, detaching a detachable joint (7; 63) between a bottom plate (5; 53) of the chromatography column and a stand (3; 43) on which the chromatography column is provided; b) attaching an adaptor (15; 59) provided in the chromatography system to any part of the chromatography column (1; 41) making it possible to lift the bottom plate (5; 53) from the stand (3; 43) with the adaptor (15; 59); and c) raising the adaptor (15; 59) and thereby also the bottom plate (5; 53) such that maintenance can be performed under the bottom plate (5; 53).Type: GrantFiled: June 16, 2011Date of Patent: March 11, 2014Assignee: GE Healthcare Bio-Sciences ABInventors: Manoj Kumar Ramakrishna, Daniel Salomonsson, Per Uselius
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Patent number: 8663477Abstract: A method for conducting maintenance on a chromatography column (1; 51), said column comprising a column tube (32), a top end cell (20) and a bottom end cell (26), where during chromatography said column tube (32) is secured between said top end cell (20) and said bottom end cell (26). Said method comprises the step of rotating at least the top end cell (20) 180 degrees around a horizontal axis before maintenance is conducted to the top end cell (20).Type: GrantFiled: June 21, 2012Date of Patent: March 4, 2014Assignee: GE Healthcare Bio-Sciences ABInventors: Per Uselius, Kyril Dambuleff, John Davis
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Publication number: 20130341482Abstract: A method for conducting maintenance on a chromatography column (1; 51), said column comprising a column tube (32), a top end cell (20) and a bottom end cell (26), where during chromatography said column tube (32) is secured between said top end cell (20) and said bottom end cell (26). Said method comprises the step of rotating at least the top end cell (20) 180 degrees around a horizontal axis before maintenance is conducted to the top end cell (20).Type: ApplicationFiled: June 21, 2012Publication date: December 26, 2013Applicant: GE HEALTHCARE BIO-SCIENCES ABInventors: PER USELIUS, KYRIL DAMBULEFF, JOHN DAVIS
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Patent number: 8585894Abstract: A nozzle assembly (1) provided in a chromatography column (3), said nozzle assembly comprising a nozzle tube (21) through which chromatography media slurry is to be provided to the column (3). According to the invention said nozzle assembly (1) further comprises a pivot (39) connected in a first end (40a) to a pivot point arm (35), said pivot (39) can be pivoted into at least two different locked pivot positions and said pivot (39) being connected to the nozzle tube (21) such that a nozzle tip (25) of said nozzle tube is adjusted into at least two different locked nozzle tip positions corresponding to the at least two different locked pivot positions.Type: GrantFiled: November 21, 2012Date of Patent: November 19, 2013Assignee: GE Healthcare Bio-Sciences ABInventor: Per Uselius
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Patent number: 8562827Abstract: In a chromatography column, at least one plastic retaining mesh is attached to a distributor plate using a fixture element comprising an elongated edge that penetrates into the plastic mesh to ensure sealing and to prevent radial movement of the plastic mesh.Type: GrantFiled: March 10, 2011Date of Patent: October 22, 2013Assignee: GE Healthcare Bio-Sciences ABInventors: Daniel Salomonsson, Petter Bennemo, Per Uselius
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Publication number: 20130087491Abstract: A method for performing maintenance on a chromatography column (1; 41) comprising the steps of: a) when maintenance is required, detaching a detachable joint (7; 63) between a bottom plate (5; 53) of the chromatography column and a stand (3; 43) on which the chromatography column is provided; b) attaching an adaptor (15; 59) provided in the chromatography system to any part of the chromatography column (1; 41) making it possible to lift the bottom plate (5; 53) from the stand (3; 43) with the adaptor (15; 59); and c) raising the adaptor (15; 59) and thereby also the bottom plate (5; 53) such that maintenance can be performed under the bottom plate (5; 53).Type: ApplicationFiled: June 16, 2011Publication date: April 11, 2013Applicant: GE HEALTHCARE BIO-SCIENCES ABInventors: Manoj Kumar Ramakrishna, Daniel Salomonsson, Per Uselius
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Publication number: 20130068671Abstract: A parallel assembly (2; 11; 51) of chromatography column modules (3a,b,c; 13a,b,c; 53a,b,c, 90a, b) connected in a rigid housing (21; 61), the assembly having one common assembly inlet (15; 55) and one common assembly outlet (17; 57), each column module comprising a bed space (29) filled with chromatography medium and each column module comprises integrated fluid conduits which when the column module is connected with other column modules in the rigid housing are adapted to connect the bed space (29) of the column module with the assembly inlet (15; 55) and the assembly outlet (17; 57), wherein the total length and/or volume of the fluid conduit from the assembly inlet to one bed space together with the length and/or volume of the fluid conduit from the same bed space to the assembly outlet is substantially the same for all bed spaces and modules installed in the parallel assembly.Type: ApplicationFiled: June 1, 2011Publication date: March 21, 2013Applicant: GE HEALTHCARE BIO-SCIENCES ABInventors: Klaus Gebauer, Manoj Kumar Ramakrishna, Daniel Salomonsson, Per Uselius
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Publication number: 20130001147Abstract: In a chromatography column, at least one plastic retaining mesh is attached to a distributor plate using a fixture element comprising an elongated edge that penetrates into the plastic mesh to ensure sealing and to prevent radial movement of the plastic mesh.Type: ApplicationFiled: March 10, 2011Publication date: January 3, 2013Applicant: GE HEALTHCARE BIO-SCIENCES ABInventors: Daniel Salomonsson, Petter Bennemo, Per Uselius
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Publication number: 20090039023Abstract: A chromatography column having a longitudinal axis and comprising a column wall with a first end and a second end, a first end plate assembly removably connectable to said first end of the column wall, a second end plate assembly removably connectable to said second end of the column wall, wherein said first end plate assembly, said column wall and said second end plate assembly are arranged along the longitudinal axis of the column wherein the column wall, and/or first end plate assembly and/or second end plate assembly is/are rotatable about an axis of rotation wherein said axis of rotation is parallel to the longitudinal axis of said column and positioned outside the column.Type: ApplicationFiled: October 14, 2008Publication date: February 12, 2009Applicant: GE HEALTHCARE BIO-SCIENCES ABInventors: PER USELIUS, Mats Olsson, Sven Woulder, Jerker Persson
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Patent number: 7452464Abstract: A chromatography column having a longitudinal axis and comprising a column wall with a first end and a second end, a first end plate assembly removably connectable to said first end of the column wall, a second end plate assembly removably connectable to said second end of the column wall, wherein said first end plate assembly, said column wall and said second end plate assembly are arranged along the longitudinal axis of the column wherein the column wall, and/or first end plate assembly and/or second end plate assembly is/are rotatable about an axis of rotation wherein said axis of rotation is parallel to the longitudinal axis of said column and positioned outside the column.Type: GrantFiled: July 18, 2005Date of Patent: November 18, 2008Assignee: GE Healthcare Bio-Sciences ABInventors: Per Uselius, Mats Olsson, Sven Wounder, Jerker Persson
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Publication number: 20060091052Abstract: A chromatography column having a longitudinal axis and comprising a column wall with a first end and a second end, a first end plate assembly removably connectable to said first end of the column wall, a second end plate assembly removably connectable to said second end of the column wall, wherein said first end plate assembly, said column wall and said second end plate assembly are arranged along the longitudinal axis of the column wherein the column wall, and/or first end plate assembly and/or second end plate assembly is/are rotatable about an axis of rotation wherein said axis of rotation is parallel to the longitudinal axis of said column and positioned outside the column.Type: ApplicationFiled: July 18, 2005Publication date: May 4, 2006Inventors: Per Uselius, Mats Olsson, Sven Wounder, Jerker Persson
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Patent number: D715957Type: GrantFiled: November 21, 2012Date of Patent: October 21, 2014Assignee: GE Healthcare Bio-Sciences ABInventor: Per Uselius