Abstract: The invention is based on a platform that has both hardware and software. The latter includes, amongst other things, an algorithm to solve the problem encountered when, on passing between countries and operators, data services have to roam between mobile networks. The invention handles and solves existing technical limitations such as existing roaming logic for switches between operators not taking into account: which services the ‘original’ operator has activated; geographical coverage; different costs for different services; and, whether services other than speech can function in the selected network.

Abstract: The invention is based on a platform that has both hardware and software. The latter includes, amongst other things, an algorithm to solve the problem encountered when, on passing between countries and operators, data services have to roam between mobile networks. The invention handles and solves existing technical limitations such as existing roaming logic for switches between operators not taking into account: which services the ‘original’ operator has activated; geographical coverage; different costs for different services; and, whether services other than speech can function in the selected network.

Abstract: The invention is based on a platform that has both hardware and software. The latter includes, amongst other things, an algorithm to solve the problem encountered when, on passing between countries and operators, data services have to roam between mobile networks. The invention handles and solves existing technical limitations such as existing roaming logic for switches between operators not taking into account: which services the ‘original’ operator has activated; geographical coverage; different costs for different services; and, whether services other than speech can function in the selected network.

Abstract: The invention is based on a platform that has both hardware and software. The latter includes, amongst other things, an algorithm to solve the problem encountered when, on passing between countries and operators, data services have to roam between mobile networks. The invention handles and solves existing technical limitations such as existing roaming logic for switches between operators not taking into account: which services the “original” operator has activated; geographical coverage; different costs for different services; and, whether services other than speech can function in the selected network.

Abstract: This invention is directed to kits for the detection of human islet amyloid polypeptide (IAPP) comprising (a) purified preparations of antibodies which react specifically with insulin or calcitonin gene-related peptides and (b) a preselected amount of human islet amyloid polypeptide which is essentially free of islet amyloid, which polypeptide is one subunit of islet amyloid and which is prepared by depolymerizing human islet amyloid; or a preselected amount of human islet amyloid polypeptide which is essentially free of islet amyloid and has the amino acid sequence: lys-cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Se r-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr.

Abstract: This invention is directed to antibodies which react with human islet amyloid polypeptide and which do not significantly react with insulin or calcitonin gene-related peptides. Preparations of antibodies are provided which bind to islet amyloid polypeptide (IAPP) which is substantially free of islet amyloid, and when isolated from humans, has the following amino acid sequence in positions 1-37:Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val- His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly- Ser-Asn-Thr-Tyr.

Abstract: Islet Amyloid Polypeptide substantially free of Islet Amyloid which can be isolated from Islet Amyloid of different mammals and when isolated from humans it has the following amino acid sequence in positions 1-37: ##STR1##

Abstract: Subunits of the full length 37 amino acid residue human Islet Amyloid Polypeptide, and feline Islet Amyloid Polypeptide essentially free of unpolymerized amyloid are provided. Islet Amyloid Polypeptide (IAPP) may be isolated and purified from amyloid fibrils using depolymerizing agent and chromatographic techniques. The sequences of the purified Islet Amyloid Polypeptides have been determined Purified Islet Amyloid Polypeptides are suitable for induction of anti-IAPP antibodies.