Patents by Inventor Pernille Ravn

Pernille Ravn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HYPERTHERMIA AUGMENTED IN-VITRO IMMUNE RECOGNITION
    Publication number: 20130078657
    Abstract: The present invention relates to a method for generation of a test-antigen specific cell-mediated immune response by incubating at hyperthermic conditions and, more particularly, a method for generation of a test-antigen specific cell-mediated immune response by incubating at hyperthermic conditions and optionally adding IL-7 and/or blocking IL-10. Even more particularly, the present invention provides a method for generating a cell-mediated response to an antigen using whole blood or other suitable bio-logical samples. The method is useful in for immune diagnosis of many infectious diseases, as a marker of immunocompetence, and for detection of T-cell responses to non-self antigens (i.e. infections and vaccines).
    Type: Application
    Filed: May 4, 2011
    Publication date: March 28, 2013
    Applicant: Hvidovre Hospital
    Inventors: Morten Ruhwald, Jesper Eugen-Olsen, Pernille Ravn, Martine Grosos Aabye
  • IP-10 BASED IMMUNOLOGICAL MONITORING
    Publication number: 20120015386
    Abstract: The present invention relates to an immunological method and, more particularly, a method for measuring cell-mediated immune reactivity (CMI) in mammals based on the production of IP-10. The invention further discloses an assay and a kit for measuring CMI to an antigen using whole blood or other suitable biological samples. The methods of the present invention are useful in therapeutic and diagnostic protocols for human, livestock and veterinary and wild life applications, thus the invention further relates to a method for diagnosing an infection in a mammal.
    Type: Application
    Filed: September 26, 2011
    Publication date: January 19, 2012
    Applicant: HVIDOVRE HOSPITAL
    Inventors: Morten Ruhwald, Pernille Ravn, Jesper Eugen-Olsen
  • IP-10 based immunological monitoring
    Patent number: 8026076
    Abstract: The present invention relates to an immunological method and, more particularly, a method for measuring cell-mediated immune reactivity (CMI) in mammals based on the production of IP-10. The invention further discloses an assay and a kit for measuring CMI to an antigen using whole blood or other suitable biological samples. The methods of the present invention are useful in therapeutic and diagnostic protocols for human, livestock and veterinary and wild life applications, thus the invention further relates to a method for diagnosing an infection in a mammal.
    Type: Grant
    Filed: September 5, 2007
    Date of Patent: September 27, 2011
    Assignee: Hvidovre Hospital
    Inventors: Morten Ruhwald, Pernille Ravn, Jesper Eugen-Olsen