Patents by Inventor Peter A. Basile

Peter A. Basile has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11878158
    Abstract: The present invention relates to drug delivery systems that cannot be reloaded or reused and further include a passive safety shield system.
    Type: Grant
    Filed: September 16, 2021
    Date of Patent: January 23, 2024
    Assignee: Merck Sharp & Dohme LLC
    Inventors: Peter A. Basile, Steven Carl Persak, Mikhail Gotliboym, Brad Britland, Stephen G. Miggels, Henry J. Mack, Oliver J. Sha
  • Patent number: 11850404
    Abstract: A manually actuated drug-injecting device is configured such that the grip strength of the entire hand (i.e., majority of fingers closing toward the palm or heel of the hand) is employed to discharge medication through a hypodermic needle and into a patient's body. The device is well suited for delivering medications with high viscosity and/or by patients (e.g., elderly patients) with reduced finger strength and dexterity. The device includes a grip member, a push member (which causes the medication to be injected), and a force-transfer mechanism that couples the grip member to the push member. Suitably, the device is configured to be held transverse to the palm of the medication-administering hand, with a discharge port located by the outer, blade edge of the administering hand, when the device is being gripped to administer medication.
    Type: Grant
    Filed: October 6, 2021
    Date of Patent: December 26, 2023
    Assignee: Merck Sharp & Dohme LLC
    Inventors: Peter A. Basile, Henry J. Mack, Jr., Oliver Sha, Stephen G. Miggels
  • Patent number: 11587463
    Abstract: A reusable safety syringe training device is provided. The device comprises a syringe contained within a syringe protective member. The syringe protective member is movable vertically within an outer protective sheath from a first position to a second position and back to the first position. In the first position, the device is in an injection-ready position with the needle exposed and the syringe protective member in a locked vertical position with respect to the outer protective sheath. In the second position, the device is in a post-injection position such that the syringe protective member is no longer vertically locked with respect to the outer protective sheath and has moved vertically upward thereby rendering the needle within the outer protective sheath. The plunger carries a release flange sufficient to engage release latches that otherwise retain the syringe protective member in the first position.
    Type: Grant
    Filed: October 13, 2017
    Date of Patent: February 21, 2023
    Assignee: MERCK SHARP & DOHME LLC
    Inventors: Peter A. Basile, Michael M. Maia
  • Publication number: 20220080128
    Abstract: A manually actuated drug-injecting device is configured such that the grip strength of the entire hand (i.e., majority of fingers closing toward the palm or heel of the hand) is employed to discharge medication through a hypodermic needle and into a patient's body. The device is well suited for delivering medications with high viscosity and/or by patients (e.g., elderly patients) with reduced finger strength and dexterity. The device includes a grip member, a push member (which causes the medication to be injected), and a force-transfer mechanism that couples the grip member to the push member. Suitably, the device is configured to be held transverse to the palm of the medication-administering hand, with a discharge port located by the outer, blade edge of the administering hand, when the device is being gripped to administer medication.
    Type: Application
    Filed: October 6, 2021
    Publication date: March 17, 2022
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Peter A. BASILE, Henry J. MACK, JR., Oliver SHA, Stephen G. MIGGELS
  • Publication number: 20220001116
    Abstract: The present invention relates to drug delivery systems that cannot be reloaded or reused and further include a passive safety shield system.
    Type: Application
    Filed: September 16, 2021
    Publication date: January 6, 2022
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Peter A. Basile, Steven Carl Persak, Mikhail Gotliboym, Brad Britland, Stephen G. Miggels, Henry J. Mack, JR., Oliver J. Sha
  • Patent number: 11173250
    Abstract: A manually actuated drug-injecting device is configured such that the grip strength of the entire hand (i.e., majority of fingers closing toward the palm or heel of the hand) is employed to discharge medication through a hypodermic needle and into a patient's body. The device is well suited for delivering medications with high viscosity and/or by patients (e.g., elderly patients) with reduced finger strength and dexterity. The device includes a grip member, a push member (which causes the medication to be injected), and a force-transfer mechanism that couples the grip member to the push member. Suitably, the device is configured to be held transverse to the palm of the medication-administering hand, with a discharge port located by the outer, blade edge of the administering hand, when the device is being gripped to administer medication.
    Type: Grant
    Filed: November 20, 2017
    Date of Patent: November 16, 2021
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Peter A. Basile, Henry J. Mack, Jr., Oliver Sha, Stephen G. Miggels
  • Patent number: 11141539
    Abstract: An injector for delivering liquid can include a body having a proximal end, a distal end, a longitudinal axis, and a track follower adjacent to the proximal end. A plunger can be disposed at least partially within the body and movable with respect to the body along the longitudinal axis. An actuator can be positioned at the proximal end of the body and operably connected to the plunger. The actuator can include a track having a first portion and a second portion. The first portion can limit travel of the actuator along the longitudinal axis to deliver a first predetermined amount of the liquid. The second portion can limit travel of the actuator along the longitudinal axis to deliver a second predetermined amount of the liquid. The actuator can be positionable to selectively control displacement of the plunger pursuant to the first portion or the second portion of the track.
    Type: Grant
    Filed: December 14, 2016
    Date of Patent: October 12, 2021
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Jeffrey C. Givand, Peter A. Basile
  • Patent number: 11123499
    Abstract: The present invention relates to drug delivery systems that cannot be reloaded or reused and further include a passive safety shield system. The drug delivery devices described herein include a drug container comprising at least one bellow, a needle, wherein the needle is in liquid communication with the drug container; a plunger extending between a proximal end and a distal end, wherein the plunger is in communication with the drug container and where upon axial movement of the plunger, the drug container is compressed.
    Type: Grant
    Filed: January 13, 2017
    Date of Patent: September 21, 2021
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Peter A. Basile, Steven Carl Persak, Mikhail Gotliboym, Brad Britland, Stephen G. Miggels, Henry J. Mack, Jr., Oliver J. Sha
  • Publication number: 20200043372
    Abstract: A reusable safety syringe training device is provided. The device comprises a syringe contained within a syringe protective member. The syringe protective member is movable vertically within an outer protective sheath from a first position to a second position and back to the first position. In the first position, the device is in an injection-ready position with the needle exposed and the syringe protective member in a locked vertical position with respect to the outer protective sheath. In the second position, the device is in a post-injection position such that the syringe protective member is no longer vertically locked with respect to the outer protective sheath and has moved vertically upward thereby rendering the needle within the outer protective sheath. The plunger carries a release flange sufficient to engage release latches that otherwise retain the syringe protective member in the first position.
    Type: Application
    Filed: October 13, 2017
    Publication date: February 6, 2020
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Peter A. Basile, Michael M. Maia
  • Patent number: 10543317
    Abstract: The present invention relates to a drug delivery device comprising a drug container having at least one bellow. The at least one bellow has a first surface and an opposing second surface. The first surface is comprised of a first Belleville spring and the opposing second surface is comprised of a second Belleville spring, wherein the second Belleville spring has a higher spring rate than the first Belleville spring.
    Type: Grant
    Filed: June 1, 2015
    Date of Patent: January 28, 2020
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Peter A. Basile, Steven Carl Persak, Mikhail Gotliboym
  • Publication number: 20190269857
    Abstract: A manually actuated drug-injecting device is configured such that the grip strength of the entire hand (i.e., majority of fingers closing toward the palm or heel of the hand) is employed to discharge medication through a hypodermic needle and into a patient's body. The device is well suited for delivering medications with high viscosity and/or by patients (e.g., elderly patients) with reduced finger strength and dexterity. The device includes a grip member, a push member (which causes the medication to be injected), and a force-transfer mechanism that couples the grip member to the push member. Suitably, the device is configured to be held transverse to the palm of the medication-administering hand, with a discharge port located by the outer, blade edge of the administering hand, when the device is being gripped to administer medication.
    Type: Application
    Filed: November 20, 2017
    Publication date: September 5, 2019
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Peter A. BASILE, Henry J. MACK, Jr., Oliver SHA, Steven G. MIGGELS
  • Publication number: 20190022336
    Abstract: The present invention relates to drug delivery systems that cannot be reloaded or reused and further include a passive safety shield system. The drug delivery devices described herein comprise a drug container comprising at least one bellow, wherein the at least one bellow comprises a first surface and an opposing second surface, wherein the first surface is comprised of a first Belleville spring and the opposing second surface is comprised of a second Belleville spring, wherein the second Belleville spring has a higher spring rate than the first Belleville spring; or a drug container extending between distal and proximal ends, and comprises a continuous change in cross section from proximal end to distal end; a needle, wherein the needle is in liquid communication with the drug container; a plunger extending between a proximal end and a distal end, wherein the plunger is in communication with the drug container and where upon axial movement of the punger, the drug container is compressed.
    Type: Application
    Filed: January 13, 2017
    Publication date: January 24, 2019
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Peter A. Basile, Steven Carl Persak, Mikhail Gotliboym, Brad Britland, Stephen G. Miggels, Henry J. Mack, Jr., Oliver J. Sha
  • Patent number: 10155088
    Abstract: A drug delivery device comprising a main body extending between distal and proximal ends comprising a hollow cylinder comprising an outer and an inner surface, wherein the inner surface comprises threads; a screw within the main body, comprising a hollow cylinder comprising an inner and an outer surface, wherein said outer surface comprises threads, wherein threads of outer surface of the screw are engaged with threads of inner surface of the main body; a plunger extending between distal and proximal ends, wherein the distal end of the plunger engages the proximal end of the screw; and a drug container extending between distal and proximal ends, and comprising a change in cross section from proximal to distal end, wherein the container is within the screw, and wherein the proximal end of the drug container is fixed to the screw and distal end of the container is fixed to the main body.
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: December 18, 2018
    Assignee: Merck Sharp & Dohme Corp.
    Inventor: Peter A. Basile
  • Publication number: 20180326157
    Abstract: An injector for delivering liquid can include a body having a proximal end, a distal end, a longitudinal axis, and a track follower adjacent to the proximal end. A plunger can be disposed at least partially within the body and movable with respect to the body along the longitudinal axis. An actuator can be positioned at the proximal end of the body and operably connected to the plunger. The actuator can include a track having a first portion and a second portion. The first portion can limit travel of the actuator along the longitudinal axis to deliver a first predetermined amount of the liquid. The second portion can limit travel of the actuator along the longitudinal axis to deliver a second predetermined amount of the liquid. The actuator can be positionable to selectively control displacement of the plunger pursuant to the first portion or the second portion of the track.
    Type: Application
    Filed: December 14, 2016
    Publication date: November 15, 2018
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Jeffrey C. Givand, Peter A. Basile
  • Patent number: 9950126
    Abstract: A medication injector that has an alert indicator that alerts the user when the medication injector is approaching near the end of its medication supply is disclosed. The alert indicator gives the user an opportunity to make preparations to obtain additional medication for the injector if there is an insufficient amount of medication in the injector to enable the user to dispense the required dosage amount with the next injection. Initially, the alert indicator is not visible to the user, but becomes visible to the user when the injector is near empty.
    Type: Grant
    Filed: December 5, 2013
    Date of Patent: April 24, 2018
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Peter A. Basile, Jeffrey C. Givand, Steven Carl Persak
  • Publication number: 20170197031
    Abstract: The present invention relates to a drug delivery device comprising a drug container comprising at least one bellow, wherein the at least one bellow comprises a first surface and an opposing second surface, wherein the first surface is comprised of a first Belleville spring and the opposing second surface is comprised of a second Belleville spring, wherein the second Belleville spring has a higher spring rate than the first Belleville spring.
    Type: Application
    Filed: June 1, 2015
    Publication date: July 13, 2017
    Inventors: Peter A. BASILE, Steven Carl PERSAK, Mikhail GOTLIBOYM
  • Publication number: 20170095625
    Abstract: A dry powder inhaler is provided herein which includes a dose chamber having a staging area configured to accommodate an inhalable dose of active pharmaceutical agent. A nozzle is provided having a discharge aperture with an inhalation channel communicating the staging area with the discharge aperture. The inhalation channel is configured such that sufficient negative pressure applied to the discharge aperture draws a dose from the staging area towards the discharge aperture. An arrangement is provided for evaluating the level of depletion of a dose from the staging area. Advantageously, the subject invention allows for evaluating physical depletion of a staged dose so as to recognize the level of delivery thereof.
    Type: Application
    Filed: May 29, 2015
    Publication date: April 6, 2017
    Applicant: MERCK SHARP & DOHME CORP.
    Inventors: PETER A. BASILE, MICHAEL GALLUPPI, MIKHAIL GOTLIBOYM, CHRISTOPHER GRANELLI, SCOTT BROWN
  • Patent number: D777907
    Type: Grant
    Filed: August 27, 2014
    Date of Patent: January 31, 2017
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Angela M. Amend Kwasnik, Benjamin R. Bartfeld, Peter Basile, Jeffrey C. Givand, Philip G. Green, Sharad Gupta, Christin L. O'Neill, Steven Carl Persak, Robert Stianchi, Ari Tao Adler, Florian Altmann, Thomas Junk, Florian Kössler, Martin Meier, Scott R. Mackie, Pernilla Danielsson
  • Patent number: D810283
    Type: Grant
    Filed: November 10, 2016
    Date of Patent: February 13, 2018
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Angela M. Amend Kwasnik, Benjamin R. Bartfield, Peter Basile, Jeffrey C. Givand, Philip G. Green, Sharad Gupta, Christin L. O'Neill, Steven Carl Persak, Robert Stianchi, Ari Tao Adler, Florian Altmann, Thomas Junk, Florian Kössler, Martin Meier, Scott R. Mackie, Pernilla Danielsson
  • Patent number: D819199
    Type: Grant
    Filed: November 11, 2016
    Date of Patent: May 29, 2018
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Angela M. Amend Kwasnik, Benjamin R. Bartfield, Peter Basile, Jeffrey C. Givand, Philip G. Green, Sharad Gupta, Christin L. O'Neill, Steven Carl Persak, Robert Stianchi, Ari Tao Adler, Florian Altmann, Thomas Junk, Florian Kössler, Martin Meier, Scott R. Mackie, Pernilla Danielsson