Patents by Inventor Peter Alan Hunt

Peter Alan Hunt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PEPTIDE TURN MIMETICS
    Publication number: 20110040087
    Abstract: Peptide mimetics of structure X herein which (i) provide a wide range of sidechain functions at all sidechain positions, (ii) can be incorporated in a peptide sequence, (iii) can be readily synthesized and (iv) have a variety of conformations. There is also provided a novel process which can provide valuable intermediates in relation to production of peptide mimetics of structure X which intermediates have a high degree of chemo- and stereo-selectivity. Preferred mimetics include structures I, II, III, IV, V and VI.
    Type: Application
    Filed: August 18, 2010
    Publication date: February 17, 2011
    Applicant: Mimetica Pty Ltd.
    Inventors: Peter Joseph Cassidy, Peter Alan Hunt, Paul Francis Alewood, Tracie Elizabeh Ramsdale
  • AMINOTHIAZOLE DERIVATIVES AS INHIBITORS OF MARK
    Publication number: 20100009987
    Abstract: Compounds of formula (I): inhibit microtubule affinity regulating kinase (MARK) and therefore find use in treatment of neurodegenerative diseases associated with hyperphosphorylation of tau.
    Type: Application
    Filed: June 1, 2007
    Publication date: January 14, 2010
    Inventors: Michela Bettati, Ian Churcher, Peter Alan Hunt, Victoria Alexandra Steadman
  • Diarylsulfones as 5-HT2A antagonists
    Patent number: 7468393
    Abstract: Compounds of formula I: are potent and selective antagonists of the human 5-HT2A receptor, and hence useful in treatment of a variety of adverse conditions of the CNS.
    Type: Grant
    Filed: April 27, 2007
    Date of Patent: December 23, 2008
    Assignee: Merck Sharp & Dohme Ltd.
    Inventors: Jose Luis Castro Pineiro, Laura Catherine Cooper, Myra Gilligan, Alexander Charles Humphries, Peter Alan Hunt, Tamara Ladduwahetty, Angus Murray MacLeod, Kevin John Merchant, Monique Bodil Van Niel, Kevin Wilson
  • 5-HTreceptor antagonists
    Patent number: 7276607
    Abstract: Substituted carbocyclic sulphonamide derivatives of formula (I), in which n is 0 or 1 and the other variables are as defined in the claims, are selective 5-HT7 receptor antagonists and are thereby effective in the treatment of a variety of neurological conditions, including depression and sleep disorders.
    Type: Grant
    Filed: November 29, 2002
    Date of Patent: October 2, 2007
    Assignee: Merck Sharp & Dohme Limited
    Inventors: Neil Roy Curtis, Peter Alan Hunt, Janusz Jozef Kulagowski
  • Pyrazole derivatives as gamma-secretase inhibitors useful in the treatment of Alzheimer's disease
    Patent number: 7271191
    Abstract: The compounds of formula I: inhibit gamma secretase and hence are of utility in the treatment or prevention of Alzheimer's Disease.
    Type: Grant
    Filed: April 1, 2004
    Date of Patent: September 18, 2007
    Assignee: Merck Sharp & Dohme Ltd.
    Inventors: Michela Bettati, Mark Stuart Chambers, Peter Alan Hunt, Philip Jones, Angus Murray MacLeod, Helen Jane Szekeres, Martin Richard Teall
  • Diarylsulfones as 5-HT2A antagonists
    Patent number: 7217740
    Abstract: Compounds of formula I: are potent and selective antagonists of the human 5-HT2A receptor, and hence useful in treatment of a variety of adverse conditions of the CNS.
    Type: Grant
    Filed: August 26, 2005
    Date of Patent: May 15, 2007
    Assignee: Merck Sharp and Dohme
    Inventors: Jose Luis Castro Pineiro, Laura Catherine Cooper, Myra Gilligan, Alexander Charles Humphries, Peter Alan Hunt, Tamara Ladduwahetty, Angus Murray MacLeod, Kevin John Merchant, Monique Bodil Van Niel, Kevin Wilson
  • Sulfone derivatives as 5-HT7 receptor ligands
    Patent number: 7101892
    Abstract: The present invention relates to sulfone derivatives of formula (I): Ar—SO2—CR2R3-L-N(R1)2I wherein Ar, L, R1, R2 and R3 are as defined herein, and pharmaceutically acceptable salts and N-oxides thereof, useful in the treatment of a condition which is susceptible to treatment by modulation of 5-HT7 receptor activity, such as depression or a sleep disorder.
    Type: Grant
    Filed: May 14, 2004
    Date of Patent: September 5, 2006
    Assignee: Merck Sharp & Dohme Ltd.
    Inventors: Sylvie Bourrain, Peter Alan Hunt, Ian Thomas Huscroft, Janusz Jozef Kulagowski, Clare London, Elizabeth Mary Naylor, Piotr Antoni Raubo, Eileen Mary Seward
  • Sulfone derivatives as 5-HT7 receptor ligands
    Publication number: 20040229864
    Abstract: The present invention relates to sulfone derivatives of formula (I):
    Type: Application
    Filed: May 14, 2004
    Publication date: November 18, 2004
    Inventors: Sylvie Bourrain, Peter Alan Hunt, Ian Thomas Huscroft, Janusz Jozef Kulagowski, Clare London, Elizabeth Mary Naylor, Piotr Antoni Raubo, Eileen Mary Seward
  • Gamma-secretase inhibitors
    Patent number: 6756511
    Abstract: Gamma-secretase inhibitors, useful in the treatment or prevention of Alzheimer's disease, are disclosed. The preferred compounds have, as the central portion of the molecule, the structure (a) and are di-astereoisomers of known protease inhibitors.
    Type: Grant
    Filed: July 18, 2002
    Date of Patent: June 29, 2004
    Assignee: Merck Sharp & Dohme Limited
    Inventors: Jose Luis Castro Pineiro, Timothy Harrison, Peter Alan Hunt, Alan John Nadin
  • Methods for classifying and searching chemical reactions
    Publication number: 20030182094
    Abstract: There is disclosed a method of characterising a chemical reaction, in terms of the structural changes occurring thereby, by means of a reaction vector value. The method may be used to identify and quantify objective similarities among members of a selected group of reactions, or between a probe reaction and members of a selected group of reactions.
    Type: Application
    Filed: February 14, 2003
    Publication date: September 25, 2003
    Inventors: Howard Barff Broughton, Peter Alan Hunt, Mark Denis MacKey
  • Gamma secretase inhibitors
    Publication number: 20030114387
    Abstract: Gamma-secretase inhibitors, useful in the treatment or prevention of Alzheimer's disease, are disclosed. The preferred compounds have, as the central portion of the molecule, the structure (a) and are diastereoisomers of known protease inhibitors.
    Type: Application
    Filed: July 18, 2002
    Publication date: June 19, 2003
    Inventors: Jose Luis Castro Pineiro, Timothy Harrison, Peter Alan Hunt, Alan John Nadin