Abstract: A dispenser cap comprising an axially moveable collar that surrounds an inner unit, the inner unit comprising a mounting ring at its bottom that is suitable for placement on a container, a cylindrical wall having a section that defines a radial outlet hole, said radial outlet hole being located towards the upper end of the inner unit, and a release trigger at the upper end of the inner unit, said collar being moveable between a raised position in which it covers the radial outlet hole and a lowered position in which it does not cover the radial outlet hole, the axially moveable collar comprising an internal structure that blocks the depression of the release trigger when the collar is in its raised position.

Abstract: A dispenser cap comprising an axially moveable collar that surrounds an inner unit, the inner unit comprising a mounting ring at its bottom that is suitable for placement on a container, a cylindrical wall having a section that defines a radial outlet hole, said radial outlet hole being located towards the upper end of the inner unit, and a release trigger at the upper and of the inner unit, said collar being moveable between a raised position in which it covers the radial outlet hole and a lowered position in which it does not cover the radial outlet hole, the axially moveable collar comprising an internal structure that blocks the depression of the release trigger when the collar is in its raised position.

Abstract: The present invention relates generally to viral variants exhibiting reduced sensitivity to particular agents and/or reduced interactivity with immunological reagents. More particularly, the present invention is directed to hepatitis B virus (HBV) variants exhibiting complete or partial resistance to nucleoside or nucleotide analogs and/or reduced interactivity with antibodies to viral surface components including reduced sensitivity to these antibodies. The present invention further contemplates assays for detecting such viral variants, which assays are useful in monitoring anti-viral therapeutic regimens and in developing new or modified vaccines directed against viral agents and in particular HBV variants. The present invention also contemplates the use of the viral variants to screen for and/or develop or design agents capable of inhibiting infection, replication and/or release of the virus.

Abstract: The present invention relates generally to viral variants exhibiting reduced sensitivity to particular agents and/or reduced interactivity with immunological reagents. More particularly, the present invention is directed to hepatitis B virus (HBV) variants exhibiting complete or partial resistance to nucleoside analogs and/or reduced interactivity with antibodies to viral surface components including reduced sensitivity to these antibodies. The present invention further contemplates assays for detecting such viral variants, which assays are useful in monitoring anti-viral therapeutic regimens and in developing new or modified vaccines directed against viral agents and in particular HBV variants. The present invention also contemplates the use of the viral variants to screen for agents capable of inhibiting infection, replication and/or release of the virus.

Abstract: A passive shimming system for a superconducting magnet to improve bore magnetic homogeneity includes a plurality of axially extending non-magnetic drawers each including a plurality of pockets along the drawer with a securable cover for each pocket to enclose the selected ferromagnetic shim disks and compressible spring material to enable individual access and shimming of selected pockets.