Patents by Inventor Peter C. Michels
Peter C. Michels has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220213428Abstract: The disclosure provides systems and methods for producing a cannabinoid product, which comprises contacting a cannabinoid precursor in a first phase with a cannabinoid synthase in a second phase, wherein the first phase and the second phase are substantially immiscible or immiscible. The disclosure also provides a composition comprising the cannabinoid precursor in a first phase and a cannabinoid synthase in a second phase, wherein the first phase and the second phase are substantially immiscible or immiscible.Type: ApplicationFiled: March 21, 2022Publication date: July 7, 2022Applicant: TEEWINOT LIFE SCIENCES CORPORATIONInventors: Richard PEET, Malcolm J. KAVARANA, Mingyang SUN, Peter C. MICHELS, John D. RABENSTEIN, C. Seth PEARSON, Geoffrey M. FOX
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Patent number: 11319525Abstract: The disclosure provides systems and methods for producing a cannabinoid product, which comprises contacting a cannabinoid precursor in a first phase with a cannabinoid synthase in a second phase, wherein the first phase and the second phase are substantially immiscible or immiscible. The disclosure also provides a composition comprising the cannabinoid precursor in a first phase and a cannabinoid synthase in a second phase, wherein the first phase and the second phase are substantially immiscible or immiscible.Type: GrantFiled: June 26, 2019Date of Patent: May 3, 2022Assignee: TEEWINOT LIFE SCIENCES CORPORATIONInventors: Richard Peet, Malcolm J. Kavarana, Mingyang Sun, Peter C. Michels, John D. Rabenstein, C. Seth Pearson, Geoffrey M. Fox
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Publication number: 20220025424Abstract: The present disclosure relates to compositions and methods for producing stereoisomerically pure aminocyclopropanes.Type: ApplicationFiled: August 16, 2017Publication date: January 27, 2022Inventors: Amy E. TAPPER, Cassandra CELATKA, Arthur Glenn ROMERO, John M. MCCALL, Toni CHANCELLOR, He ZHAO, Betina BIOLATTO, Jian-Xie CHEN, Elisabeth C.A. BROT, Peter C. MICHELS, Venkat K. CHARI, Ian C. COTTERILL
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Publication number: 20190382708Abstract: The disclosure provides systems and methods for producing a cannabinoid product, which comprises contacting a cannabinoid precursor in a first phase with a cannabinoid synthase in a second phase, wherein the first phase and the second phase are substantially immiscible or immiscible. The disclosure also provides a composition comprising the cannabinoid precursor in a first phase and a cannabinoid synthase in a second phase, wherein the first phase and the second phase are substantially immiscible or immiscible.Type: ApplicationFiled: June 26, 2019Publication date: December 19, 2019Inventors: Richard PEET, Malcolm J. KAVARANA, Mingyang SUN, Peter C. Michels, John D. Rabenstein, C. Seth Pearson, Geoffrey M. Fox
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Patent number: 10336978Abstract: The disclosure provides systems and methods for producing a cannabinoid product, which comprises contacting a cannabinoid precursor in a first phase with a cannabinoid synthase in a second phase, wherein the first phase and the second phase are substantially immiscible or immiscible. The disclosure also provides a composition comprising the cannabinoid precursor in a first phase and a cannabinoid synthase in a second phase, wherein the first phase and the second phase are substantially immiscible or immiscible.Type: GrantFiled: May 10, 2018Date of Patent: July 2, 2019Assignee: TEEWINOT TECHNOLOGIES LIMITEDInventors: Richard Peet, Malcolm J. Kavarana, Mingyang Sun, Peter C. Michels, John D. Rabenstein, C. Seth Pearson, Geoffrey M. Fox
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Publication number: 20180346866Abstract: The disclosure provides systems and methods for producing a cannabinoid product, which comprises contacting a cannabinoid precursor in a first phase with a cannabinoid synthase in a second phase, wherein the first phase and the second phase are substantially immiscible or immiscible. The disclosure also provides a composition comprising the cannabinoid precursor in a first phase and a cannabinoid synthase in a second phase, wherein the first phase and the second phase are substantially immiscible or immiscible.Type: ApplicationFiled: May 10, 2018Publication date: December 6, 2018Applicant: TEEWINOT TECHNOLOGIES LIMITEDInventors: Richard PEET, Malcolm J. KAVARANA, Mingyang SUN, Peter C. Michels, John D. Rabenstein, C. Seth Pearson, Geoffrey M. Fox
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Publication number: 20140179624Abstract: Disclosed herein are novel cytoprotective derivatives of avicin D, including those of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising these derivative compounds. Methods and intermediates useful for making the derivatives, and methods of using the derivatives and compositions thereof, including for the treatment of cancer, are also provided.Type: ApplicationFiled: December 20, 2013Publication date: June 26, 2014Applicant: Research Development FoundationInventors: Jordan GUTTERMAN, Valsala HARIDAS, Peter C. MICHELS, Yuri L. KHMELNITSKY, Vadim M. MOZHAEV
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Patent number: 8754054Abstract: The present invention relates to novel therapeutics with antibacterial activity, processes for their preparation, and pharmaceutical, veterinary and nutritional compositions containing them as active ingredients. The present invention also relates to uses of the novel therapeutics, for example, as medicants or food additives in the treatment of bacterial infections or to aid body mass gain in a subject.Type: GrantFiled: September 17, 2010Date of Patent: June 17, 2014Assignee: Albany Molecular Research, Inc.Inventors: Grant J. Carr, David D. Manning, Zhicai Yang, Cheng Guo, Jun-Ho Maeng, Peter C. Michels, Matthew W. Chase
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Publication number: 20130237490Abstract: The present invention relates to novel therapeutics with antibacterial activity, processes for their preparation, and pharmaceutical, veterinary and nutritional compositions containing them as active ingredients. The present invention also relates to uses of the novel therapeutics, for example, as medicants or food additives in the treatment of bacterial infections or to aid body mass gain in a subject.Type: ApplicationFiled: September 17, 2010Publication date: September 12, 2013Applicant: Albany Molecular Research, Inc.Inventors: Grant J. CARR, David D. MANNING, Zhicai YANG, Cheng GUO, Jun-Ho MAENG, John RABENSTEIN, Peter C. MICHELS, Matthew W. CHASE
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Publication number: 20120010163Abstract: The present invention relates to novel therapeutics with antibacterial activity, processes for their preparation, and pharmaceutical, veterinary and nutritional compositions containing them as active ingredients. The present invention also relates to uses of the novel therapeutics, for example, as medicants or food additives in the treatment of bacterial infections or to aid body mass gain in a subject.Type: ApplicationFiled: September 17, 2010Publication date: January 12, 2012Applicant: Albany Molecular Research, Inc.Inventors: GRANT J. CARR, DAVID D. MANNING, ZHICAL YANG, CHENG GUO, JUN-HO MAENG, JOHN RABENSTEIN, PETER C. MICHELS, MATTHEW W. CHASE
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Patent number: 7842122Abstract: A gas remover apparatus suitable for electrical substation high-voltage transformer load tap changers and similar oil-filled equipment removes potentially hazardous and destructive gases from the air-filled volume above the insulating oil bath in which the load tap changer electrical contacts are immersed. The apparatus applies a continuous supply of nitrogen to the load tap changer, and has an orifice to maintain a slight overpressure over an extreme range of climatic conditions. The substantially continuous venting of nitrogen entrains and expels contaminants such as oxygen, water, and potentially explosive breakdown products from the oil, all of which can degrade the performance of the load tap changer.Type: GrantFiled: October 31, 2003Date of Patent: November 30, 2010Assignee: Waukesha Electric Systems IncorporatedInventors: Thomas M. Golner, Peter C. Michel
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Patent number: 7691615Abstract: The present invention relates to the production of a product compound having a structure according to Formulae IA and/or IB: wherein n is 0 or 1; R1 is hydrogen or hydroxy; R2 is hydrogen; or, when n is 0, R1 and R2 taken together form a second bond between the carbon atoms bearing R1 and R2, provided that when n is 1, R1 and R2 are each hydrogen; R3 is —COOH or —COOR4; R4 is an alkyl or aryl moiety; A, B, and D are the substituents of their rings, each of which may be different or the same, and are selected from the group consisting of hydrogen, halogens, alkyl, hydroxy, and alkoxy. This process involves incubating a starting compound having a structure according to Formulae IIA and/or IIB: wherein R3 is —CH3 and R1, R2, A, B, and D are defined above in the presence of a microorganism under conditions effective to produce the product compound.Type: GrantFiled: January 17, 2007Date of Patent: April 6, 2010Assignee: Albany Molecular Research, Inc.Inventors: Peter C. Michels, Eric L. Zirbes
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Patent number: 7538084Abstract: The compounds of the present invention are represented by the chemical structure found in Formula I: Formula I where A is an amino acid of Formula II: or a pharmaceutically acceptable salt thereof, with R0, R1, B, C, D, E, F, G, H, I, J, and K defined herein.Type: GrantFiled: March 16, 2004Date of Patent: May 26, 2009Assignee: AMR Technology, Inc.Inventors: Bruce F. Molino, Simon N. Haydar, Zhicai Yang, Peter C. Michels, Michael S. Hemenway, Joseph O. Rich, Yuri Khmelnitsky
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Patent number: 7232908Abstract: The present invention relates to a process for the production of piperidine derivatives with microorganisms. This is carried out by incubating starting compounds in the presence of a microorganism under conditions effective to produce piperidine derivative products. Suitable microorganisms can be from any one of the genus of Stemphylium, Gliocladium, Bacillus, Botrytis, Cyathus, Rhizopus, Pycniodosphora, Pseudomonas, Helicostylum, Mucor, Gelasinospora, Rhodotorula, Candida, Mycobacterium, and Penicillium. In another aspect of the invention, starting compounds are incubated in the presence of Cunninghamella bainieria under conditions effective to produce piperidine derivative products.Type: GrantFiled: August 11, 2003Date of Patent: June 19, 2007Assignee: AMR Technology, Inc.Inventors: Peter C. Michels, Eric L. Zirbes
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Publication number: 20040235716Abstract: The compounds of the present invention are represented by the chemical structure found in Formula I: 1 Formula I 1Type: ApplicationFiled: March 16, 2004Publication date: November 25, 2004Inventors: Bruce F. Molino, Simon N. Haydar, Zhicai Yang, Peter C. Michels, Michael S. Hemenway, Joseph O. Rich, Yuri Khmelnitsky
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Patent number: 6613907Abstract: The present invention relates to the production of a product compound having a structure according to Formulae IA and/or IB: wherein n is 0 or 1; R1 is hydrogen or hydroxy; R2 is hydrogen; or, when n is 0, R1 and R2 taken together form a second bond between the carbon atoms bearing R1 and R2, provided that when n is 1, R1 and R2 are each hydrogen; R3 is —COOH or —COOR4; R4 is an alkyl or aryl moiety; A, B, and D are the substituents of their rings, each of which may be different or the same, and are selected from the group consisting of hydrogen, halogens, alkyl, hydroxy, and alkoxy. This process involves incubating a starting compound having a structure according to Formulae IIA and/or IIB: wherein R3 is —CH3 and R1, R2, A, B, and D are defined above In the presence of a microorganism under conditions effective to produce the product compound.Type: GrantFiled: January 4, 2001Date of Patent: September 2, 2003Assignee: AMR Technology, Inc.Inventors: Peter C. Michels, Eric L. Zirbes
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Patent number: 6568287Abstract: An oil sampling system for an electrical power device in which the oil flows through the sampling device in a closed loop with the oil containing apparatus of the electrical power device. Oil is taken in from an active region near the top of the oil containing apparatus and returned to a lower region thereof. This assures that the oil sample is representative of the oil in the system. For the case of a power transformer, the oil flow is by cooling with gravity assistance. For the case of a pumped system, such as a load tap changer, the oil flow is forced. The sampling procedure begins with connecting the sampling device in the closed loop. Oil is then passed through the sampling device until bubble free. The sampling device is then removed for analysis. The procedure does not need a flush operation or a flush container.Type: GrantFiled: December 29, 2000Date of Patent: May 27, 2003Assignee: Waukesha Electric SystemsInventors: Thomas M. Golner, Peter C. Michel
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Patent number: 6465625Abstract: Highly specific biocatalytic reactions have been used to create a population of taxol derivatives.Type: GrantFiled: June 19, 2000Date of Patent: October 15, 2002Assignee: Albany Molecular Research, Inc.Inventors: Jonathan S. Dordick, Douglas S. Clark, Peter C. Michels, Yuri L. Khmelnitsky
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Publication number: 20020083781Abstract: An oil sampling system for an electrical power device in which the oil flows through the sampling device in a closed loop with the oil containing apparatus of the electrical power device. Oil is taken in from an active region near the top of the oil containing apparatus and returned to a lower region thereof. This assures that the oil sample is representative of the oil in the system. For the case of a power transformer, the oil flow is by cooling with gravity assistance. For the case of a pumped system, such as a load tap changer, the oil flow is forced. The sampling procedure begins with connecting the sampling device in the closed loop. Oil is then passed through the sampling device until bubble free. The sampling device is then removed for analysis. The procedure does not need a flush operation or a flush container.Type: ApplicationFiled: December 29, 2000Publication date: July 4, 2002Inventors: Thomas M. Golner, Peter C. Michel
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Publication number: 20020087003Abstract: The present invention relates to the production of a product compound having a structure according to Formulae IA and/or IB: 1Type: ApplicationFiled: January 4, 2001Publication date: July 4, 2002Inventors: Peter C. Michels, Eric L. Zirbes