Patents by Inventor Peter C. Rahn
Peter C. Rahn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10603604Abstract: A slurry chamber is fastened to and held in coaxial alignment with a chromatography column by a V-band. One end of the column has an end cap and frit. A slurry of fluid and chromatographic media is placed in the column and chamber. A piston is forced through the chamber and into the column by a hydraulic ram to expel the fluid and form a media bed in the column. The slurry chamber is removed, and a split end cap is fastened to the column. A threaded recess in the split end cap receives a split, threaded collet. The collet is tightened until it pushes against the piston with the same force as the ram, at which point the ram is released and the column removed for use.Type: GrantFiled: July 19, 2017Date of Patent: March 31, 2020Assignee: Phenomenex, Inc.Inventors: Peter C. Rahn, Romaine R. Maiefski, Tivadar Farkas, Emmet E. Welch
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Publication number: 20180078877Abstract: A slurry chamber is fastened to and held in coaxial alignment with a chromatography column by a V-band. One end of the column has an end cap and frit. A slurry of fluid and chromatographic media is placed in the column and chamber. A piston is forced through the chamber and into the column by a hydraulic ram to expel the fluid and form a media bed in the column. The slurry chamber is removed, and a split end cap is fastened to the column. A threaded recess in the split end cap receives a split, threaded collet. The collet is tightened until it pushes against the piston with the same force as the ram, at which point the ram is released and the column removed for use.Type: ApplicationFiled: July 19, 2017Publication date: March 22, 2018Inventors: Peter C. Rahn, Romaine R. Maiefski, Tivadar Farkas, Emmet E. Welch
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Publication number: 20100181240Abstract: A slurry chamber is fastened to and held in coaxial alignment with a chromatography column by a V-band. One end of the column has an end cap and frit. A slurry of fluid and chromatographic media is placed in the column and chamber. A piston is forced through the chamber and into the column by a hydraulic ram to expel the fluid and form a media bed in the column. The slurry chamber is removed, and a split end cap is fastened to the column. A threaded recess in the split end cap receives a split, threaded collet. The collet is tightened until it pushes against the piston with the same force as the ram, at which point the ram is released and the column removed for use.Type: ApplicationFiled: January 22, 2010Publication date: July 22, 2010Applicant: Phenomenex, Inc.Inventors: Peter C. Rahn, Romaine R. Maiefski, Tivadar Farkas, Emmet E. Welch
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Publication number: 20100126921Abstract: A slurry chamber is fastened to and held in coaxial alignment with a chromatography column by a V-band. One end of the column has an end cap and fit. A slurry of fluid and chromatographic media is placed in the column and chamber. A piston is forced through the chamber and into the column by a hydraulic ram to expel the fluid and form a media bed in the column. The slurry chamber is removed, and a split end cap is fastened to the column. A threaded recess in the split end cap receives a split, threaded collet. The collet is tightened until it pushes against the piston with the same force as the ram, at which point the ram is released and the column removed for use.Type: ApplicationFiled: February 3, 2010Publication date: May 27, 2010Applicant: Phenomenex, Inc.Inventors: Peter C. Rahn, Romaine R. Maiefski, Tivadar Farkas, Emmet E. Welch
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Patent number: 7674383Abstract: A slurry chamber is fastened to and held in coaxial alignment with a chromatography column by a V-band. One end of the column has an end cap and frit. A slurry of fluid and chromatographic media is placed in the column and chamber. A piston is forced through the chamber and into the column by a hydraulic ram to expel the fluid and form a media bed in the column. The slurry chamber is removed, and a split end cap is fastened to the column. A threaded recess in the split end cap receives a split, threaded collet. The collet is tightened until it pushes against the piston with the same force as the ram, at which point the ram is released and the column removed for use.Type: GrantFiled: October 25, 2005Date of Patent: March 9, 2010Assignee: Phenomenex, Inc.Inventors: Peter C. Rahn, Romaine R. Maiefski, Tivadar Farkas, Emmet E. Welch
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Patent number: 7063784Abstract: A method of processing a sample comprising introducing a sample into a flow-through device containing a porous solid media therein, and thereafter subjecting the device to microwave energy.Type: GrantFiled: December 15, 2003Date of Patent: June 20, 2006Assignee: Biotage ABInventors: Shahnaz Ghassemi Jamalabadi, Peter C. Rahn, Kelvin J. Hammond, Omar Mneimne, Jeffrey A. Horsman, Peter C. Van Davelaar
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Patent number: 6802968Abstract: An apparatus for use in liquid chromatography involves a column filled with media bounded axially by first and second porous plates. The column has an inlet end with an inflow region between the inlet end and the first porous plate. The column also has an outlet end with an outflow region between the outlet end and the second porous plate. The inflow region may be substantially longer than the outflow region. The porous plates may be moveable under pressure so as to compress the media.Type: GrantFiled: June 14, 2002Date of Patent: October 12, 2004Assignee: Biotage, Inc.Inventors: Peter J. Leavesley, Peter C. Van Davelaar, Robert D. Lockman, Ivan Hargro, Jeffrey A. Horsman, Peter C. Rahn
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Publication number: 20040188354Abstract: A method of processing a sample comprising introducing a sample into a flow-through device containing a porous solid media therein, and thereafter subjecting the device to microwave energy.Type: ApplicationFiled: December 15, 2003Publication date: September 30, 2004Inventors: Shahnaz Ghassemi Jamalabadi, Peter C. Rahn, Kelvin J. Hammond, Omar Mneimne, Jeffrey A. Horsman, Peter C. Van Davelaar
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Patent number: 6649051Abstract: A method of processing a sample comprising introducing a sample into a flow-through device containing a porous solid media therein, and thereafter subjecting the device to microwave energy. Also disclosed is a flow through device including solid porous media therein and attached active components.Type: GrantFiled: May 1, 2002Date of Patent: November 18, 2003Assignee: Biotage, Inc.Inventors: Shahnaz Ghassemi Jamalabadi, Peter C. Rahn, Kelvin Hammond, Omar Mneimne, Jeffrey A. Horsman
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Publication number: 20030205456Abstract: A method of processing a sample comprising introducing a sample into a flow-through device containing a porous solid media therein, and thereafter subjecting the device to microwave energy.Type: ApplicationFiled: December 17, 2002Publication date: November 6, 2003Inventors: Shahnaz Ghassemi Jamalabadi, Peter C. Rahn, Kelvin J. Hammond, Omar Mneimne, Jeffrey A. Horsman
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Publication number: 20030205455Abstract: A method of processing a sample comprising introducing a sample into a flow-through device containing a porous solid media therein, and thereafter subjecting the device to microwave energy. Also disclosed is a flow through device including solid porous media therein and attached active components.Type: ApplicationFiled: May 1, 2002Publication date: November 6, 2003Inventors: Shahnaz Ghassemi Jamalabadi, Peter C. Rahn, Kelvin Hammond, Omar Mneimne, Jeffrey A. Horsman
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Publication number: 20020153294Abstract: An apparatus for use in liquid chromatography involves a column filled with media bounded axially by first and second porous plates. The column has an inlet end with an inflow region between the inlet end and the first porous plate. The column also has an outlet end with an outflow region between the outlet end and the second porous plate. The inflow region may be substantially longer than the outflow region. The porous plates may be moveable under pressure so as to compress the media.Type: ApplicationFiled: June 14, 2002Publication date: October 24, 2002Applicant: Biotage, Inc., a Delaware corporationInventors: Peter J. Leavesley, Peter C. Van Davelaar, Robert D. Lockman, Ivan Hargro, Jeffrey A. Horsman, Peter C. Rahn
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Patent number: 6436284Abstract: An apparatus for use in liquid chromatography involves a column filled with media bounded axially by at least one porous member. The column has an inlet end with an inflow region between the inlet and a porous member. The inflow region may be sufficiently long so that a chromatography sample module may be disposed therein. The column may be sufficiently long so that a chromatography sample module may be disposed therein. The column may also have an outlet end with an outflow region between the outlet end and a second porous member. The inflow region may be substantially longer than the outflow region. The porous members may be moveable relative to the column.Type: GrantFiled: October 13, 2000Date of Patent: August 20, 2002Assignee: Biotage, Inc.Inventors: Peter J. Leavesley, Peter C. Van Davelaar, Robert D. Lockman, Ivan Hargo, Jeffrey A. Horsman, Peter C. Rahn
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Patent number: 6294087Abstract: A chromatography column includes a tubular member with an inlet end and a slidable porous member that bounds a chromatography media. The porous member is spaced sufficiently from the inlet end to define a receiving region.Type: GrantFiled: April 12, 2000Date of Patent: September 25, 2001Assignee: Dyax CorporationInventors: Ivan Hargro, Jeffrey A. Horsman, Peter C. Rahn, Peter C. Van Davelaar
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Patent number: 6221252Abstract: A chromatography sample module including a flow-through member having an inlet and an outlet, chromatography media within the flow-through member, and a sample carried on the media. The module can fit within a chromatography column, and a plurality of modules can be arranged in an array in a rack to facilitate processing of multiple samples.Type: GrantFiled: April 12, 2000Date of Patent: April 24, 2001Assignee: Dyax CorporationInventors: Ivan Hargro, Jeffrey A. Horsman, Peter C. Rahn, Peter C. Van Davelaar
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Patent number: 6139733Abstract: A chromatography sample module including a flow-through member having an inlet and an outlet, chromatography media within the flow-through member, and a sample carried on the media. The module can fit within a chromatography column, and a plurality of modules can be arranged in an array in a rack to facilitate processing of multiple samples.Type: GrantFiled: August 20, 1998Date of Patent: October 31, 2000Assignee: Dyax CorporationInventors: Ivan Hargro, Jeffrey A. Horsman, Peter C. Rahn, Peter C. Van Davelaar
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Patent number: 6019897Abstract: Apparatus for simultaneously supplying solvent to a plurality of chromatography columns using a plurality of pumps. Each pump has a chamber with a movable solvent piston therein and inflow and outflow valves. The outflow valve of each pump is connected to a respective chromatography column. The solvent pistons are simultaneously moved in one direction to pull solvent into the respective chambers until all pistons have achieved an adjustable stop position corresponding to a desired delivery volume. The solvent pistons are then simultaneously moved in the opposite direction to deliver solvent to the respective columns until all pistons have delivered the desired delivery volumes. The solvent pistons are driven by a common pneumatic or hydraulic system.Type: GrantFiled: August 20, 1998Date of Patent: February 1, 2000Assignee: Dyax CorporationInventors: Jeffrey A. Horsman, Peter J. Leavesley, Peter C. Rahn, Thomas R. Schumacher, Peter C. Van Davelaar