Abstract: The invention relates to the production of biofuels, proteins, peptides and other value-added compounds from crude carbon sources. The inventors identified genes encoding novel pentose transporters, in particular transporters of L-arabinose and/or D-xylose. Regulation of the Aspergillus niger genes by xlnR and araR was instrumental in the identification of these genes and their substrate specificities. Provided are novel pentose transporters and their encoding nucleic acids. Also provided are host cells (over)expressing a transporter, and industrial applications thereof, for instance in biofuel production.

Abstract: Embodiments of the present invention are directed toward providing a method utilizing project management software for creating a project plan utilizing a top-down strategy allowing a user to describe high-level objectives before filling in details for the underlying tasks of which the high-level objectives are comprised. As an alternative to basing summary task dates and durations solely on subtask data, the present invention allows a user to enter dates and duration values into summary tasks regardless of when the corresponding subtasks occur. By utilizing a top-down project management approach, embodiments of the present invention promote utilizing summary tasks as a starting point of project planning. Users are able to input high-level objectives of a project when more specific details of subtasks are unknown. Because summary task data is not rolled-up from the subtask data, a user may specify details such as dates and durations of subtasks at a later time.

Abstract: A project management application provides an environment in which a user can transform a project sketch, which is based on mostly “freeform” data, into a defined project plan. The project management application facilitates the mixture of freeform task attribute values with structured attribute values of one or more project tasks. The project management application can utilize an internal calculation model to manage the relationships between task attribute values despite accepting freeform values for task attributes. The project management application calculates the attribute values to the extent allowed by the calculation model's recognition of the attribute values.

Abstract: A method of and system for handling allocation of task work to resources with flexibly configured availability contours (work calendars) is disclosed. The method includes defining one or more base calendars, a resource calendar associated with each resource, wherein the resource calendar inherits from a base calendar. A calendar reader, a set of recurring exception records, and a set of effective weeks for each calendar are also defined. For a specific date, the method determines whether an exception exists in one of the base calendar and resource calendar, and if an exception exists, computes a cached effective week honoring the exception data from an associated recurring exception record. If an exception does not exist, a cached effective week for the resource is computed from a combination of the calendar's standard week and associated effective week records.

Abstract: Embodiments of the present invention are directed toward providing a method utilizing project management software for creating a project plan utilizing a top-down strategy allowing a user to describe high-level objectives before filling in details for the underlying tasks of which the high-level objectives are comprised. As an alternative to basing summary task dates and durations solely on subtask data, the present invention allows a user to enter dates and duration values into summary tasks regardless of when the corresponding subtasks occur. By utilizing a top-down project management approach, embodiments of the present invention promote utilizing summary tasks as a starting point of project planning. Users are able to input high-level objectives of a project when more specific details of subtasks are unknown. Because summary task data is not rolled-up from the subtask data, a user may specify details such as dates and durations of subtasks at a later time.

Abstract: We describe a recombinant host cell for the production of a compound of interest as well as isolated fungal promoter DNA sequences, to DNA constructs, vectors, and fungal host cells comprising these promoters in operative association with coding sequences encoding a compound of interest. We also describe methods for expressing a gene of interest and/or producing compounds of interest using a promoter according to the invention.

Abstract: A project management application is provided in which an active or not active task state for each task may be displayed in a user interface. The active or not active task state would indicate whether the task is inactive or active. If the state of a task is active, the project management application may treat the active task as a normal task in the project plan. If the state of a task is inactive, the project management application may treat the inactive task as having no effect and may ignore the inactive task for scheduling purposes in the project plan. The project management application may maintain and display information of the inactive tasks in the project plan. The project management application may display the inactive tasks in a different style from the active tasks in the user interface.

Abstract: Technologies are described herein for showing and correcting irregularities in a schedule. A project management application allows a user to manually define tasks within a schedule. The application evaluates the manually defined tasks to determine if the tasks cause an irregularity within the schedule. If so, the application provides one or more visual indications of the irregularity to the user. The application also provides functionality for allowing a user to resolve or ignore the irregularity.

Abstract: A project management application provides an environment in which a user can transform a project sketch, which is based on mostly “freeform” data, into a defined project plan. The project management application facilitates the mixture of freeform task attribute values with structured attribute values of one or more project tasks. The project management application can utilize an internal calculation model to manage the relationships between task attribute values despite accepting freeform values for task attributes. The project management application calculates the attribute values to the extent allowed by the calculation model's recognition of the attribute values.

Abstract: The invention provides polyglutamic acid-therapeutic agent conjugates and methods for their preparation and use.

Abstract: The invention provides polyglutamic acid-therapeutic agent conjugates and methods for their preparation and use.

Abstract: A method of and system for handling allocation of task work to resources with flexibly configured availability contours (work calendars) is disclosed. The method includes defining one or more base calendars, a resource calendar associated with each resource, wherein the resource calendar inherits from a base calendar. A calendar reader, a set of recurring exception records, and a set of effective weeks for each calendar are also defined. For a specific date, the method determines whether an exception exists in one of the base calendar and resource calendar, and if an exception exists, computes a cached effective week honoring the exception data from an associated recurring exception record. If an exception does not exist, a cached effective week for the resource is computed from a combination of the calendar's standard week and associated effective week records.

Abstract: The invention includes a magnetic recording head that has at least one structure or substructure that is made of a semiconductor material that protects the head from damage or destruction arising from stray current flow or unwanted electrostatic discharge during manufacture, assembly or use. The semiconductor material acts as a dissipative pathway to drain unwanted charges from the structure. The invention also includes a magnetic recording head that includes a substrate and a reader portion in the substrate, the substrate comprising a semiconductor material.

Abstract: The invention provides polyglutamic acid-therapeutic agent conjugates and methods for their preparation and use.

Abstract: The invention provides polyglutamic acid-therapeutic agent conjugates and methods for their preparation and use.

Abstract: Recombinantly produced &agr;-glucuronidases which are useful in food manufacturing and as a feed additive to enhance the utilization of the feed components, and in other industrial applications such as pulp processing are provided. Genes coding for such enzymes can e.g. be isolated from Aspergillus sp. including A. tubigensis or A. niger.

Abstract: The invention provides polyglutamic acid-therapeutic agent conjugates and methods for their preparation and use.

Abstract: The invention provides polyglutamic acid-therapeutic agent conjugates and methods for their preparation and use.

Abstract: The invention provides polyglutamic acid-therapeutic agent conjugates and methods for their preparation and use.

Abstract: A refuse handling assembly for use with a vehicle, including a receptacle for receiving refuse the receptacle having a delivery inlet opening at the forward end of the receptacle and a discharge outlet opening at the rearward end of the receptacle. The receptacle is operatively mounted to the vehicle for pivotal movement about a pivot mounting at or near the rear end of the vehicle for pivotal movement between a lowered position and a tilted position. There is further provided a compactor at the delivery inlet opening having a sweep blade which has its pivot axis laterally offset with respect to the longitudinal axis of the receptacle.