Patents by Inventor Peter DUBRUEL

Peter DUBRUEL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240060216
    Abstract: Fibrous materials are provided that comprise a cross-linkable urethane-based polymer (CUP) and an oligomeric or macromonomeric urethane-based cross-linker. The fibrous materials may be used in hydrogels, in filtration devices, in affinity membranes, in (protective) clothing, in drug delivery systems, and in tissue scaffolds, for example. The fibrous materials are useable also in human and/or veterinary medicine, such as in skin care and/or wound care.
    Type: Application
    Filed: September 11, 2020
    Publication date: February 22, 2024
    Inventors: Arn MIGNON, Tom GHEYSENS, Sandra VAN VLIERBERGHE, Peter DUBRUEL
  • Patent number: 11732084
    Abstract: Hydrogels are provided that include an antimicrobial agent and a cross-linkable urethane-based polymer (CUP). Such hydrogels may be used for the controlled-release of antimicrobial agents as well as in the manufacturing of wound dressings. Wound dressings are provided that comprise a hydrogel as defined herein.
    Type: Grant
    Filed: September 11, 2020
    Date of Patent: August 22, 2023
    Assignee: UNIVERSITEIT GENT
    Inventors: Arn Mignon, Tom Gheysens, Sandra Van Vlierberghe, Peter Dubruel
  • Publication number: 20220325030
    Abstract: Hydrogels are provided that include an antimicrobial agent and a cross-linkable urethane-based polymer (CUP). Such hydrogels may be used for the controlled-release of antimicrobial agents as well as in the manufacturing of wound dressings. Wound dressings are provided that comprise a hydrogel as defined herein.
    Type: Application
    Filed: September 11, 2020
    Publication date: October 13, 2022
    Inventors: Arn Mignon, Tom GHEYSENS, Sandra VAN VLIERBERGHE, Peter DUBRUEL
  • Publication number: 20210388151
    Abstract: The present invention in general relates to acrylate end-capped urethane-based polymers, which are in particular characterized by the presence of at least 3 acrylate end-groups, thereby making them particularly suitable for further processing using multiple kinds of technologies such as 2-photon polymerization, stereolithography (SLA printing), electrospinning, film casting, porogen leaching, extrusion based 3D-printing, spray drying, cryogenic treatment, coatings, cross-linkable micelles, spincoating, and electrospraying.
    Type: Application
    Filed: November 5, 2019
    Publication date: December 16, 2021
    Applicants: Universiteit Gent, Allnex Belgium SA
    Inventors: Aysu Arslan, Hugues van den Bergen, Patrice Roose, Dirk Bontinck, Sandra van Vlierberghe, Peter Dubruel
  • Patent number: 11192977
    Abstract: The present invention relates to poly(alkylene terephthalate) polyesters having long poly-methylene segments and their use in a wide variety of applications. Particularly, said PAT polyesters are used in biotechnological or biomedical applications, wherein the extent of cell adhesion, cell growth or cell interaction, in particular endothelial cells, depends on the odd or even number of carbon atoms in the aliphatic segments. Also provided are methods for the preparation of poly(alkylene terephthalates) (PAT) having long poly-methylene segments, wherein the bifunctional monomers, in particular terephthalic acid (or a derivative thereof) and an aliphatic diol, are dissolved in a solvent and the polycondensation reaction takes place in solution.
    Type: Grant
    Filed: March 23, 2017
    Date of Patent: December 7, 2021
    Assignee: UNIVERSITEIT GENT
    Inventors: Elena Diana Giol, Peter Dubruel, Sandra Van Vlierberghe
  • Patent number: 11098155
    Abstract: The invention pertains to the technical field of urethane based materials, in particular to radiation curable urethane precursors that are cross-linkable in solid form and materials obtainable therefrom. In addition the invention pertains to methods for manufacturing these precursors and materials, and their uses. The invention is advantageous to the fields of i.e. coatings and biomedical applications.
    Type: Grant
    Filed: January 24, 2020
    Date of Patent: August 24, 2021
    Assignee: UNIVERSITEIT GENT
    Inventors: Peter Dubruel, Sandra Van Vlierberghe, Annemie Houben, Hugues Van Den Bergen, Patrice Roose, Dirk Bontinck
  • Publication number: 20200157274
    Abstract: The invention pertains to the technical field of urethane based materials, in particular to radiation curable urethane precursors that are cross-linkable in solid form and materials obtainable therefrom. In addition the invention pertains to methods for manufacturing these precursors and materials, and their uses. The invention is advantageous to the fields of i.e. coatings and biomedical applications.
    Type: Application
    Filed: January 24, 2020
    Publication date: May 21, 2020
    Applicants: Universiteit Gent, Allnex Beligum SA
    Inventors: Peter Dubruel, Sandra Van Vlierberghe, Annemie Houben, Hugues Van Den Bergen, Patrice Roose, Dirk Bontinck
  • Patent number: 10584199
    Abstract: The invention pertains to the technical field of urethane based materials, in particular to radiation curable urethane precursors that are cross-linkable in solid form and materials obtainable therefrom. In addition the invention pertains to methods for manufacturing these precursors and materials, and their uses. The invention is advantageous to the fields of i.e. coatings and biomedical applications.
    Type: Grant
    Filed: June 30, 2016
    Date of Patent: March 10, 2020
    Assignees: UNIVERSITEIT GENT, ALLNEX BELGIUM SA
    Inventors: Peter Dubruel, Sandra Van Vlierberghe, Annemie Houben, Hugues Van Den Bergen, Patrice Roose, Dirk Bontinck
  • Publication number: 20190031824
    Abstract: The present invention relates to poly(alkylene terephthalate) polyesters having long poly-methylene segments and their use in a wide variety of applications. Particularly, said PAT polyesters are used in biotechnological or biomedical applications, wherein the extent of cell adhesion, cell growth or cell interaction, in particular endothelial cells, depends on the odd or even number of carbon atoms in the aliphatic segments. Also provided are methods for the preparation of poly(alkylene terephthalates) (PAT) having long poly-methylene segments, wherein the bifunctional monomers, in particular terephthalic acid (or a derivative thereof) and an aliphatic diol, are dissolved in a solvent and the polycondensation reaction takes place in solution.
    Type: Application
    Filed: March 23, 2017
    Publication date: January 31, 2019
    Inventors: Elena Diana GIOL, Peter DUBRUEL, Sandra VAN VLIERBERGHE
  • Publication number: 20180194890
    Abstract: The invention pertains to the technical field of urethane based materials, in particular to radiation curable urethane precursors that are cross-linkable in solid form and materials obtainable therefrom. In addition the invention pertains to methods for manufacturing these precursors and materials, and their uses. The invention is advantageous to the fields of i.e. coatings and biomedical applications.
    Type: Application
    Filed: June 30, 2016
    Publication date: July 12, 2018
    Applicants: Universiteit Gent, Allnex Belgium SA
    Inventors: Peter DUBRUEL, Sandra VAN VLIERBERGHE, Annemie HOUBEN, Hugues VAN DEN BERGEN, Patrice ROOSE, Dirk BONTINCK
  • Patent number: 9062194
    Abstract: A method for preparing a solid composite material comprising a structural polymer matrix and a thermo-responsive hydrogel involves forming a substantially homogeneous blend of a cross-linkable compound and monomer, oligomer or polymer particles in a blended aqueous liquid, inducing the cross-linkable compound to cross-link to form the thermo-responsive hydrogel and forming the structural polymer matrix from the structural polymer by a further induction means, wherein the resulting solid composite material provides a textile or membrane which presents a thermally insulating layer, through which air and/or liquid water cannot easily pass at low temperatures, but which also provides a more open structure at higher temperatures so that air and moisture vapor can pass through the textile or membrane.
    Type: Grant
    Filed: November 5, 2012
    Date of Patent: June 23, 2015
    Assignees: WETENSCHAPPELIJK EN TECHNISCH CENTRUM VAN DE BELGISCHE TEXTIELNIJVERHEID, UNIVERSITEIT GENT
    Inventors: Geert Hebbrecht, Peter Dubruel, Myriam Vanneste, Jan Laperre, Etienne Schacht, Jorg Schelfhout
  • Publication number: 20130245606
    Abstract: A hydrogel based occlusion system, a method for occluding vessels, appendages or aneurysms, and a method for hydrogel synthesis are disclosed. The hydrogel based occlusion system includes a hydrogel having a shrunken and a swollen state and a delivery tool configured to deliver the hydrogel to a target occlusion location. The hydrogel is configured to permanently occlude the target occlusion location in the swollen state. The hydrogel may be an electro-activated hydrogel (EAH) which could be electro-activated with a delivery system to control the degree of swelling/shrinking.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 19, 2013
    Applicants: UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK, UNIVERSITEIT GENT, TECHNISCHE UNIVERSITEIT DELFT, RAMOT AT TEL-AVIV UNIVERSITY, LTD., KATHOLIEKE UNVIVERSITEIT LEUVEN - KU LEUVEN RESEARCH & DEVELOPMENT, INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM VZW
    Inventors: Frank Albert STAM, Nathan JACKSON, Peter DUBRUEL, Kehinde ADESANYA, Anika EMBRECHTS, Eduardo MENDES, JR., Hurcules Pereira NEVES, Paul HERIJGERS, Peter VERBRUGGHE, Yosi SHACHAM, Leeya ENGEL, Viacheslav KRYLOV