Abstract: Disclosed is a method of increasing the rate of delivery of an active compound or agent to the brain across the blood brain barrier of a subject. In one aspect, the disclosure provides an accelerated method of providing an active compound to a targeted region of the brain of a subject, served by the cerebral medial artery, the method comprising: administering a sub-anesthetic dose of xenon as an inhalant to the subject; and administering an efficacious amount of the active compound to the bloodstream of the subject, the active compound reaching the targeted region of the brain in less time relative to a time it takes to reach the targeted region without xenon administration.

Abstract: This disclosure relates to methods of determining if a subject not manifesting any clinical symptoms of a dopaminergic disorder is afflicted with the dopaminergic disorder using radiolabeled DatT020 or a derivative thereof.

Abstract: A filtering device for fluids which includes a barrel with an open end and a flow discharge end. A plunger is slidably disposed in the barrel through the open end toward the discharge end and an exhaust nipple projects from the discharge end. The nipple is in communication with the interior of the barrel. A filter is disposed adjacent the barrel inwardly of and adjacent to the discharge nipple, and an annular, integral support stand is disposed at the discharge end of the barrel and surrounds the nipple. The nipple terminates at a point spaced from a planar surface defined by the support stand, which surface is normal to the axis of the barrel and the direction of movement of the plunger whereby the device will stand on a surface with the exhaust nipple spaced from the surface.

Abstract: A filtering device of the piston-cylinder type having a piston (P) and a cylinder (C) with reduced cross-sections (36) and (16) to create a pressurization chamber to force all fluids within the closed end of the cylinder into the piston as the piston is urged toward the closed end of the cylinder.