Patents by Inventor Peter Herwig Maria Tomme

Peter Herwig Maria Tomme has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for identification, and compounds useful for the treatment of degenerative & inflammatory diseases
    Patent number: 7306923
    Abstract: The present invention relates to in vivo and in vitro methods, agents and compound screening assays for inhibiting extra-cellular matrix degradation, including joint degenerative inhibiting and/or anti-inflammatory pharmaceutical compositions, and the use thereof in treating and/or preventing a disease involving extra-cellular matrix degradation in a subject.
    Type: Grant
    Filed: June 14, 2005
    Date of Patent: December 11, 2007
    Assignee: Galapagos N.V.
    Inventors: Reginald Brys, Nick Vandeghinste, Peter Herwig Maria Tomme
  • Modulators of bone homeostasis identified in a high-throughput screen
    Publication number: 20030119771
    Abstract: The invention relates to the field of molecular genetics and medicine. In particular, the present invention relates to the field of functional genomics, i.e., to a method for the identification of genes that function in regulating bone homeostasis, such as the induction of osteogenesis.
    Type: Application
    Filed: August 22, 2002
    Publication date: June 26, 2003
    Inventors: Luc Van Rompaey, Helmuth Hendrikus Gerardus Van Es, Peter Herwig Maria Tomme, Hubertus Johannes Matheus Klaassen
  • Adenoviral library assay for E2F regulatory genes and methods and compositions for screening compounds
    Publication number: 20030059794
    Abstract: The invention relates to the field of molecular genetics and medicine. In particular the present invention relates to the field of functional genomics. The present invention provides the methods and means for the identification of nucleic acids and the polypeptides encoded by these nucleic acids that have a function related to the E2F pathway, which were isolated in a high-throughput screening assay using the E2F transcription factor activity as a read-out. The identified compounds are suitable drug-targets to treat human diseases.
    Type: Application
    Filed: March 5, 2002
    Publication date: March 27, 2003
    Inventors: Ronald Vogels, Abraham Bout, Helmuth van Es, Govert Schouten, Rene Bernards, Godefridus A.M. Michiels, Reginald C.X. Brys, Peter Herwig Maria Tomme