Patents by Inventor Peter Klimko

Peter Klimko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HETEROCYCLIC INHIBITORS OF HISTAMINE RECEPTORS FOR THE TREATMENT OF DISEASE
    Publication number: 20110257137
    Abstract: The present invention relates to compounds and methods which may be useful as inhibitors of H1R and/or H4R for the treatment or prevention of inflammatory, autoimmune, allergic, and ocular diseases.
    Type: Application
    Filed: March 10, 2011
    Publication date: October 20, 2011
    Applicant: KALYPSYS, INC.
    Inventors: Allen Borchardt, Robert Davis, Clay Beauregard, Daniel Becker, Daniel Gamache, Stewart A. Noble, Mark Hellberg, Peter Klimko, Zhihai Qiu, Joseph Payne, John Yanni
  • HETEROCYCLIC INHIBITORS OF HISTAMINE RECEPTORS FOR THE TREATMENT OF DISEASE
    Publication number: 20110237599
    Abstract: The present invention relates to compounds and methods which may be useful as inhibitors of H1R and/or H4R for the treatment or prevention of inflammatory, autoimmune, allergic, and ocular diseases.
    Type: Application
    Filed: March 9, 2011
    Publication date: September 29, 2011
    Applicant: Kalypsys, Inc.
    Inventors: Allen Borchardt, Robert Davis, Clay Beauregard, Daniel Gamache, Mark Hellberg, Peter Klimko, John Yanni
  • Method of Treating Asthma, Allergic Rhinitis, and Skin Disorders
    Publication number: 20080108695
    Abstract: The use of 5,6,7-trihydroxyheptanoic acid and analogs is disclosed for the treatment of asthma, allergic rhinitis, and skin disorders such as allergic dermatitis, contact hypersensitivity, urticaria (hives), rosacea, or psoriasis.
    Type: Application
    Filed: November 6, 2007
    Publication date: May 8, 2008
    Applicant: Alcon Manufacturing Ltd.
    Inventors: Peter Klimko, Clay Beauregard, Bryon Severns
  • SUPEROXIDE DISMUTASE-2 EXPRESSION AND MODULATION FOR GLAUCOMA DIAGNOSIS AND THERAPY
    Publication number: 20080085878
    Abstract: The present invention concerns a method for diagnosing or monitoring elevated intraocular pressure or glaucoma in a patient comprising providing a biological sample from the patient and measuring the expression level of a superoxide dismutase-2 (SOD-2) gene in the biological sample. The present invention also concerns methods for treating glaucoma or elevated intraocular pressure in a patient comprising administering to a patient an effective amount of an agent that modulates SOD-2 expression or SOD-2 activity.
    Type: Application
    Filed: February 28, 2007
    Publication date: April 10, 2008
    Applicant: ALCON MANUFACTURING, LTD.
    Inventors: Wan-Heng WANG, Loretta McNatt, Abbot CLARK, Peter KLIMKO
  • CONTROL OF INTRAOCULAR PRESSURE USING ALK5 MODULATION AGENTS
    Publication number: 20070142376
    Abstract: An ophthalmic pharmaceutical composition useful in the treatment of glaucoma and control of intraocular pressure comprising an effective amount of a selective modulator of ALK5 receptor activity is disclosed. Also disclosed is a method of treating glaucoma and controlling intraocular pressure comprising applying a therapeutically effective amount of a pharmaceutical composition comprising a selective modulator of ALK5 receptor activity to an affected eye of a patient.
    Type: Application
    Filed: December 15, 2006
    Publication date: June 21, 2007
    Applicant: ALCON, INC.
    Inventors: Debra FLEENOR, Iok-Hou PANG, Allan SHEPARD, Mark HELLBERG, Abbot CLARK, Peter KLIMKO
  • Superoxide dismutase mimics for the treatment of optic nerve and retinal damage
    Publication number: 20070060557
    Abstract: Methods for preventing and treating damage to the optic nerve and/or retina by the use of SOD mimics, particularly pentaazacycle Mn(II) complex SOD mimics, are disclosed.
    Type: Application
    Filed: November 30, 2004
    Publication date: March 15, 2007
    Inventor: Peter Klimko
  • Method of reducing intraocular pressure and treating glaucoma
    Publication number: 20060154981
    Abstract: The use of 5,6,7-trihydroxyheptanoic acid and analogs for the treatment of ocular hypertension and glaucoma is disclosed.
    Type: Application
    Filed: January 12, 2006
    Publication date: July 13, 2006
    Inventors: Peter Klimko, Mark Hellberg, Wan-Heng Wang, Abbot Clark, Loretta McNatt
  • Method of treating dry eye disorders using 13(S)-HODE and its analogs
    Publication number: 20060128803
    Abstract: The topical use of 13(S)-HODE and analogs are disclosed for the treatment of dry eye disorders.
    Type: Application
    Filed: December 14, 2005
    Publication date: June 15, 2006
    Inventors: Peter Klimko, Daniel Gamache, Gustav Graff, Mark Hellberg, John Falck, John Yanni
  • 5,6,7-Trihydroxyheptanoic acid and analogs for the treatment of ocular diseases and diseases associated with hyperproliferative and angiogenic responses
    Publication number: 20060099248
    Abstract: Compositions containing 5,6,7-trihydroxyheptanoic acid and analogs and their use for treating posterior segment ocular diseases and diseases characterized by cellular hyperproliferation or angiogenesis, are disclosed.
    Type: Application
    Filed: November 8, 2005
    Publication date: May 11, 2006
    Inventors: Peter Klimko, Mark Hellberg, David Bingaman, Daniel Gamache
  • Superoxide dismutase mimics for the treatment of ocular disorders and diseases
    Publication number: 20060089343
    Abstract: The use of SOD mimics, particularly Mn(III) porphyrin complexes, for the treatment of AMD, DR, and retinal edema is disclosed.
    Type: Application
    Filed: December 5, 2003
    Publication date: April 27, 2006
    Inventors: Peter Klimko, Robert Collier, Mark Hellberg
  • Histone deacetylase inhibitors for the treatment of ocular neovascular or edematous disorders and diseases
    Publication number: 20060074100
    Abstract: Ophthalmic compositions containing HDAC inhibitors and their use for treating ocular neovascular or edematous diseases and disorders are disclosed.
    Type: Application
    Filed: October 30, 2003
    Publication date: April 6, 2006
    Inventors: Peter Klimko, David Bingaman
  • Method of treating dry eye disorders and uveitis
    Publication number: 20060058375
    Abstract: The topical use of 5,6,7-trihydroxyheptanoic acid and analogs are disclosed for the treatment of dry eye disorders and uveitis.
    Type: Application
    Filed: November 7, 2005
    Publication date: March 16, 2006
    Inventors: Peter Klimko, Mark Hellberg, Daniel Gamache
  • Superoxide dismutase mimics for the treatment of ocular disorders and diseases
    Publication number: 20060035880
    Abstract: The use of SOD mimics, particularly Mn(III) salen SOD mimics, for the treatment of AMD, DR, and retinal edema is disclosed.
    Type: Application
    Filed: December 5, 2003
    Publication date: February 16, 2006
    Inventors: Peter Klimko, Robert Collier, Mark Hellberg
  • Inhibitors of adenosine kinase for the treatment of optic nerve and retinal damage
    Publication number: 20050282769
    Abstract: Methods for preventing and treating damage to the optic nerve and/or retina with adenosine kinase inhibitors are disclosed.
    Type: Application
    Filed: July 18, 2005
    Publication date: December 22, 2005
    Inventor: Peter Klimko
  • Method of treating dry eye disorders and uveitis
    Publication number: 20050256189
    Abstract: The topical use of 5,6,7-trihydroxyheptanoic acid and analogs are disclosed for the treatment of dry eye disorders and uveitis.
    Type: Application
    Filed: May 12, 2005
    Publication date: November 17, 2005
    Inventors: Peter Klimko, Mark Hellberg, Daniel Gamache
  • Superoxide dismutase mimics for the treatment of optic nerve and retinal damage
    Publication number: 20050130951
    Abstract: Methods for preventing and treating damage to the optic nerve and/or retina by the use of SOD mimics, particularly pentaazacycle Mn(II) complex SOD mimics, are disclosed.
    Type: Application
    Filed: November 30, 2004
    Publication date: June 16, 2005
    Inventor: Peter Klimko
  • Superoxide dismutase mimics for the treatment of ocular disorders and diseases
    Publication number: 20050032768
    Abstract: The use of SOD mimics particularly pentsaaacycle Mn(II) complex SOD mimics, for the treatment of AMD, DR, and retinal edema is disclosed.
    Type: Application
    Filed: December 6, 2002
    Publication date: February 10, 2005
    Inventors: Peter Klimko, Robert Collier Jr., Mark Hellberg