Patents by Inventor Peter M. Stewart

Peter M. Stewart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of inhibiting muscle protein degradation
    Patent number: 4677121
    Abstract: Muscle protein breakdown or degradation may be reduced or inhibited in mammals, particularly humans recovering from surgery or suffering from a muscle wasting disorder, by administering daily doses of alpha-ketoisocaproic acid (ketoleucine) or an appropriate salt of the acid. Seventy millimoles per day of sodium alpha-ketoisocaproate administered for five days after major abdominal surgery was found to significantly reduce urinary 3-methylhistidine/creatinine, which is a measure of muscle protein breakdown, and thereby to improve nitrogen balance.
    Type: Grant
    Filed: October 31, 1985
    Date of Patent: June 30, 1987
    Assignee: The Johns Hopkins University
    Inventors: Mackenzie Walser, Daniel G. Sapir, Peter M. Stewart