Patents by Inventor Peter Michael Andreoli

Peter Michael Andreoli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transformed industrial bacillus strains and methods for making and using them
    Patent number: 6083718
    Abstract: Novel methods and novel industrial unicellular microorganism strains, particularly industrial Bacillus strains, are provided for enhanced production of endogenous and exogenous polypeptides. Cloning vehicles containing the gene expressing the polypeptide of interest are introduced into a compatible host. Transformed hosts harboring the introduced vehicle in a stable way by integration of the vehicle into the host cells chromosome are selected. Efficient transfer of the vehicle containing the gene of interest is achieved, with the resulting industrial strain transformants being effective, stable producers of the desired polypeptide product.
    Type: Grant
    Filed: November 5, 1997
    Date of Patent: July 4, 2000
    Assignee: Gist-Brocades, N.V.
    Inventors: Johan Pieter Marinus Sanders, Johannes Abel Van Den Berg, Peter Michael Andreoli, Yvonne Johanna Vos, Jan Hendrik Van Ee, Leo J. S. M. Mulleners
  • Cloning and expression of DNA molecules incoding arabinan-degrading enzymes of fungal origin
    Patent number: 5989887
    Abstract: The present invention provides the cloning and expression of purified and isolated DNA molecules, obtainable from fungi, which encode enzymes having arabinan-degrading activity. The present invention also provides DNA constructs containing these DNA molecules and methods for their enhanced expression in selected microbial host cells. The present invention further provides methods for the use of the thus-produced arabinan-degrading enzymes.
    Type: Grant
    Filed: August 18, 1997
    Date of Patent: November 23, 1999
    Assignee: DSM N.V.
    Inventors: Margaretha Van Heuvel, Janna Gardina Bakhuis, Yves Coutel, Abraham Harder, Leendert Hendrik De Graaff, Michel Johannes Anthonie Flipphi, Peter Van Der Veen, Jacob Visser, Peter Michael Andreoli
  • Cloning and expression of DNA molecules encoding arabinan-degrading enzymes of fungal origin
    Patent number: 5863783
    Abstract: The present invention provides the cloning and expression of purified and isolated DNA molecules, obtainable from fungi, which encode enzymes having arabinan-degrading activity. The present invention also provides DNA constructs containing these DNA molecules and methods for their enhanced expression in selected microbial host cells. The present invention further provides methods for the use of the thus-produced arabinan-degrading enzymes.
    Type: Grant
    Filed: November 25, 1992
    Date of Patent: January 26, 1999
    Assignee: Gist-brocades, N.V.
    Inventors: Margaretha Van Heuvel, Janna Gardina Bakhuis, Yves Coutel, Abraham Harder, Leendert Hendrick De Graaff, Michel Johannes Anthonie Flipphi, Peter Van Der Veen, Jacob Visser, Peter Michael Andreoli
  • Method for producing lipolytic enzymes using transformed Pseudomonas
    Patent number: 5830735
    Abstract: Novel microbial host strains are provided which are transformed by a vector molecule comprising a DNA fragment encoding a lipolytic enzyme and a marker for selection, capable of producing active lipase. Said DNA fragment is preferably derived from a Pseudomonas species.
    Type: Grant
    Filed: December 1, 1992
    Date of Patent: November 3, 1998
    Assignee: Gist-Brocades NV
    Inventors: Peter Michael Andreoli, Maria Mathilde Josphina Cox, Farrokh Farin, Suzanne Wohlfarth-Rippel
  • Transformed industrial bacillus strains and methods for making and using them
    Patent number: 5716807
    Abstract: Novel methods and novel industrial unicellular microorganism strains, particularly industrial Bacillus strains, are provided for enhanced production of endogenous and exogenous polypeptides. Cloning vehicles containing the gene expressing the polypeptide of interest are introduced into a compatible host. Transformed hosts harboring the introduced vehicle in a stable way by integration of the vehicle into the host cells chromosome are selected. Efficient transfer of the vehicle containing the gene of interest is achieved, with the resulting industrial strain transformants being effective, stable producers of the desired polypeptide product.
    Type: Grant
    Filed: August 16, 1996
    Date of Patent: February 10, 1998
    Assignee: Gist-Brocades
    Inventors: Johan Pieter Marinus Sanders, Johannes Abel Van den Berg, Peter Michael Andreoli, Yvonne Johanna Vos, Jan Hendrik van Ee, Leo J. S. M. Mulleners