Abstract: A thermoset material containing ?-hydroxyesters wherein said thermoset material is subject to a mechano-chemical process to regenerate an epoxide and a carboxylic acid functionality. A curative for epoxidized plant-based oils and epoxidized natural rubber is created from the reaction between a naturally occurring polyfunctional acid and an epoxidized plant-based oil is disclosed. The curative may be used to produce porosity-free castable resins and vulcanize rubber formulations based on epoxidized natural rubber. Materials made from disclosed materials may be advantageously used as leather substitutes.

Abstract: A dielectric waveguide to transmit an electromagnetic signal, comprises: a first conductor region and a second conductor region. The first and second conductor regions extend along a longitudinal axis of the dielectric waveguide, wherein the first conductor region is formed from a first thermoplastic material and the second conductor region is formed from a second thermoplastic material. The first thermoplastic material has a higher effective permittivity than the second thermoplastic material.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for training a neural network that includes one or more graph neural network layers. In one aspect, a method comprises: generating data defining a graph, comprising: generating a respective final feature representation for each node, wherein, for each of one or more of the nodes, the respective final feature representation is a modified feature representation that is generated from a respective feature representation for the node using respective noise; processing the data defining the graph using one or more of the graph neural network layers of the neural network to generate a respective updated node embedding of each node; and processing, for each of one or more of the nodes having modified feature representations, the updated node embedding of the node to generate a respective de-noising prediction for the node.

Abstract: The present invention is directed to certain (hetero)aroyl 4-aminopyrazole derivatives of Formula (I) and pharmaceutically acceptable salts thereof, wherein A, R1, R2, and R3 are as defined herein, which are potent inhibitors of LRRK2 kinase and may be useful in the treatment or prevention of diseases in which the LRRK2 kinase is involved, such as Parkinson's Disease and other diseases and disorders described herein. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which LRRK-2 kinase is involved.

Abstract: A neural stimulus comprises at least three stimulus components, each comprising at least one of a temporal stimulus phase and a spatial stimulus pole. A first stimulus component delivers a first charge which is unequal to a third charge delivered by a third stimulus component, and the first charge and third charge are selected so as to give rise to reduced artefact at recording electrodes. In turn this may be exploited to independently control a correlation delay of a vector detector and an artefact vector to be non-parallel or orthogonal.

Abstract: A system includes a housing and a first circuit board positioned inside the housing. The housing has a top panel, a bottom panel, a left side panel, a right side panel, a front panel, and a rear panel. The front panel is at an angle relative to the bottom panel in which the angle is in a range from 30 to 150°. The first circuit board has a length, a width, and a thickness, in which the length is at least twice the thickness, the width is at least twice the thickness, and the first circuit board has a first surface defined by the length and the width. The first surface of the first circuit board is at a first angle relative to the bottom panel in which the first angle is in a range from 30 to 150°. The first surface of the first circuit board is substantially parallel to the front panel or at a second angle relative to the front panel in which the second angle is less than 60°.

Abstract: Sensor systems can be used to measure an analyte concentration. Sensor systems can include a base having a distal side configured to face towards a person's skin. An adhesive can couple the base to the skin. A transcutaneous analyte measurement sensor can be coupled to the base and can be located at least partially in the host. A transmitter can be coupled to the base and can transmit analyte measurement data to a remote device.

Abstract: A system including a plurality of photovoltaic shingles installed on a roof deck, a plurality of roofing shingles, such as asphalt shingles, installed on the roof deck, and a plurality of step flaps. One end of the roofing shingle overlays a first side of a corresponding one of the step flaps, and one end of photovoltaic shingle overlays a second side of the corresponding one of the step flaps.

Abstract: The present disclosure provides controllers for power distribution network circuit interrupting devices and provides electronic control circuits for inclusion in such controllers. The electronic control circuit has a boost circuit, a capacitor storage unit and a pulse width modulator control circuit. The boost circuit boosts an input voltage to a value to supply sufficient energy to a protective relay solenoid to energize the solenoid. The capacitor storage unit stores the boosted voltage from the boost circuit. The pulse width modulator control circuit is responsive to a control and enable circuit to selectively enable energy from the capacitor to energize the one or more protective relays in power distribution system circuit interrupting device.

Abstract: An endoluminal punch and introducer sheath are described wherein the endoluminal punch comprises a guidewire lumen through which a user is capable of placing a guidewire. The endoluminal punch system further comprises a mechanism affixed to the hub which is capable of controlling the axial positioning of the guidewire relative to the endoluminal punch distal end. The control mechanism can be released so that the endoluminal punch can be removed from a patient while retaining the guidewire in place within the patient. The endoluminal punch introducer, including a sheath and dilator, can comprise energy emitting electrodes or transducers for cutting larger size holes in stubborn (friable, scarred, or fibrotic) tissue. In other embodiments, the endoluminal punch can comprise a guidewire or stylet, wherein the guidewire or stylet is capable of emitting energy to cut through tissue.