Abstract: Disclosed is a centrifugal microconcentrator and methods for using the microconcentrator to concentrate macromolecules from a solution without filtering to dryness and to centrifugally recover a maximal amount of concentrated macromolecular retentate.

Abstract: Particles having a mean diameter from 0.1 to 50 micrometers and having a solid core of water-impermeable polyacrylonitrile and a partially hydrolyzed hydrophilic surface layer enclosing the core containing from 0.001 to 0.8 milliequivalents of carboxyl or carboxylate groups per dry gram, the surface layer amounting to 0.01 to 20% by weight of the particles, are useful as a solid phase insoluble support to which biospecific reagents such as antigens or antibodies can be coupled. Variants include supports in which N-hydroxysuccinimide or various spacer arms are coupled to the carboxyl or carboxylate groups.

Abstract: A process for separating blood plasma from whole blood that dispenses with the known centrifugal-separation techniques and involves passing whole blood along a flow path which is shallow and substantially parallel to the upstream side of filtration membrane, recovering plasma from the downstream side of said membrane, and recovering the retained blood components (formed elements) from the upstream side of the membrane. .Iadd .