Abstract: A training device for training a trainee to operate a defibrillator including a housing having a shape which imitates a shape of a defibrillator, a defibrillator function emulation device attached to the housing and configured to emulate a predefined subset of functions of a defibrillator, and electrodes attached to the housing. The trainer defibrillator of the disclosure simulates a real defibrillator, but, due to limited functionality and construction, will be much less expensive than existing trainer defibrillators and will therefore be able to be distributed more widely.

Abstract: A training device for training a trainee to operate a defibrillator including a housing having a shape which imitates a shape of a defibrillator, a defibrillator function emulation device attached to the housing and configured to emulate a predefined subset of functions of a defibrillator, and electrodes attached to the housing. The trainer defibrillator of the disclosure simulates a real defibrillator, but, due to limited functionality and construction, will be much less expensive than existing trainer defibrillators and will therefore be able to be distributed more widely.

Abstract: A process of forming a tissue scaffold is described, the process comprising electrospinning polymer fibers from a spinneret onto a tissue scaffold template. In embodiments, the fibers are plasma-treated between the spinneret and the template. The scaffold may be constructed of alternating layers of aligned and randomly oriented fibers. The scaffold may be heat treated to control the mechanical properties of the scaffold, such as density, pore size and pore interconnectivity.

Abstract: A process of forming a tissue scaffold is described, the process comprising electrospinning polymer fibers from a spinneret onto a tissue scaffold template. In embodiments, the fibers are plasma-treated between the spinneret and the template. The scaffold may be constructed of alternating layers of aligned and randomly oriented fibers. The scaffold may be heat treated to control the mechanical properties of the scaffold, such as density, pore size and pore interconnectivity.

Abstract: Disclosed herein are methods of modifying a nitinol surface by using abrasive blasting techniques. The surface modification can be performed by abrasively blasting the surface and delivering at least one dopant from one or more fluid jets to cause the at least one dopant to impregnate and/or coat the nitinol surface. The nitinol surface can form a portion or all of a medical device, such as an implantable medical device, e.g., a stent.

Abstract: This invention relates to aggregated compositions comprising short peptides, or sub-sequences, of full length VP22 protein for delivery of substances such as nucleic acids and proteins into cells. The invention relates to such compositions in themselves, and to methods for their manufacture and use.