Patents by Inventor Peter P. McCann

Peter P. McCann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polyamine derivatives
    Patent number: 5753714
    Abstract: This invention relates to certain polyamine derivatives, to the methods and intermediates useful for their preparation, and to their use in treating diseases caused by infestation with a variety of parasitic protozoa.
    Type: Grant
    Filed: March 15, 1994
    Date of Patent: May 19, 1998
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: David M. Stemerick, Alan J. Bitonti, Michael L. Edwards, Peter P. McCann, Albert Sjoerdsma
  • Despiramine in the treatment of drug-resistant malarial infections
    Patent number: 5373005
    Abstract: Drug-resistant malarial infection in humans can be effectively treated with standard antimalarial agents if administered in conjunction with desipramine.
    Type: Grant
    Filed: March 5, 1993
    Date of Patent: December 13, 1994
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Peter P. McCann, Albert Sjoerdsma, Alan J. Bitonti
  • Esters of castanospermine in the treatment of cerebral malaria
    Patent number: 5214050
    Abstract: Red blood cells which are infected with the parasite P. falciparum cause the cells to become sticky and less deformable. This results in a build-up of cells on the vascular wall and creates occlusions to blood flow which are thought to cause the cerebral, renal and liver complications of P. falciparum infections. Certain esters of castanospermine prevent or reduce the adhesion of falciparum infected blood cells to the vascular endothelial wall and are a useful adjunct in the treatment of malaria.
    Type: Grant
    Filed: March 5, 1992
    Date of Patent: May 25, 1993
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Alan J. Bitonti, Peter P. McCann, Albert Sjoerdsma
  • Method of inhibiting protozoal growth
    Patent number: 5196450
    Abstract: This invention relates to the use of .alpha.- halomethyl, .alpha.-acetylenic or .alpha.-allenic derivatives of arginine and agmatine, or their dehydro analogs, in the treatment of Chagas disease and Coccidiosis.
    Type: Grant
    Filed: September 30, 1991
    Date of Patent: March 23, 1993
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Albert Sjoerdsma, Peter P. McCann, Philippe Bey, Patrick J. Casara
  • Method of controlling phytopathogenic fungus
    Patent number: 4760091
    Abstract: This invention relates to a method of controlling phytopathogenic rust and smut fungi of the Uredinales order in a plant locus which comprises applying a fungicidally effective amount of an ornithine decarboxylase inhibitor.
    Type: Grant
    Filed: February 18, 1987
    Date of Patent: July 26, 1988
    Assignee: The Dow Chemical Company
    Inventors: Chrislyn M. Carson, Peter P. McCann
  • Method of inhibiting the growth of protozoa
    Patent number: 4399151
    Abstract: .alpha.-Substituted amines and .alpha.-substituted-.alpha.-amino acids are described which are useful in inhibiting the growth of protozoa in animals.
    Type: Grant
    Filed: May 11, 1981
    Date of Patent: August 16, 1983
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Albert Sjoerdsma, Peter P. McCann