Patents by Inventor Peter Paul Zilla
Peter Paul Zilla has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20120059447Abstract: A stent deployment device (1) over which a stent (2) is securable for the purpose of delivery into an operative position in a human body is provided. The device comprises a plurality of elongate wings (16), each of which has a length consistent with the length of a stent to be deployed using the deployment device, the wings being arranged circumferentially about a central body (10) which extends from, and is operable through, a catheter (14). The wings are movable between a radially withdrawn delivery position and expanded positions in which they are displaced radially outwards of the body. A flow path (105) is defined internally of the wings in the expanded positions thereof and a temporary valve (68) is provided in such flow path to permit the flow of blood though the flow path predominantly in one direction. An inflatable annular balloon (80) is preferably provided over the wings to cause final expansion of the stent.Type: ApplicationFiled: October 8, 2009Publication date: March 8, 2012Applicant: SOUTHERN ACCESS TECHNOLOGIES (PTY) LIMITEDInventors: Peter Paul Zilla, Deon Bezuidenhout, David Franklyn Williams
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Publication number: 20110213454Abstract: A vascular prosthesis is constructed from a structure having interconnected, helically oriented channel-porosity to allow oriented ingrowth of connective tissue into a wall of the prosthesis. The prosthesis can have a small internal diameter of 6 mm or less. Several different methods can be used to produce the prosthesis, including a fiber winding and extraction technique, a melt extrusion technique, and a particle and fiber extraction technique using either a layered method or a continuous method. Furthermore, mechanical properties of prosthesis are matched with mechanical properties of the host vessel, thereby overcoming problems of compliance mismatch.Type: ApplicationFiled: May 14, 2010Publication date: September 1, 2011Inventors: Peter Paul Zilla, Deon Bezuidenhout
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Patent number: 7998188Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.Type: GrantFiled: May 4, 2007Date of Patent: August 16, 2011Assignee: Kips Bay Medical, Inc.Inventors: Peter Paul Zilla, Nasser Rafiee, Deon Bezuidenhout, Thomas Franz, Mark Yeoman, Hellmut Bowles, Nareak Douk, Michael F. Wolf, Paul Human
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Patent number: 7632306Abstract: A vascular prosthesis is constructed from a well-defined pore structure to allow uninterrupted ingrowth of connective tissue into a wall of the prosthesis. Several different methods can be used to produce the prosthesis, including a vacuum impregnation technique, a paste molding technique, a paste extrusion technique, a dip coating technique, and a melt extrusion technique. Furthermore, mechanical properties of the prosthesis are matched with mechanical properties of the host vessel, thereby overcoming problems of compliance mismatch.Type: GrantFiled: July 2, 2003Date of Patent: December 15, 2009Assignee: Medtronic, Inc.Inventors: Peter Paul Zilla, Deon Bezuidenhout
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Patent number: 7033388Abstract: A vascular prosthesis is constructed from a structure having interconnected, helically oriented channel-porosity to allow oriented ingrowth of connective tissue into a wall of the prosthesis. The prosthesis can have a small internal diameter of 6 mm or less. Several different methods can be used to produce the prosthesis, including a fiber winding and extraction technique, a melt extrusion technique, and a particle and fiber extraction technique using either a layered method or a continuous method. Furthermore, mechanical properties of the prosthesis are matched with mechanical properties of the host vessel, thereby overcoming problems of compliance mismatch.Type: GrantFiled: July 2, 2002Date of Patent: April 25, 2006Assignee: Medtronic, Inc.Inventors: Peter Paul Zilla, Deon Bezuidenhout
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Patent number: 7022135Abstract: A vascular graft prosthesis having ingrowth-permissive lumenal wall features with a thin film or layer of sealant-like material placed at a lumenal wall location to promote improved transmural tissue growth and healing.Type: GrantFiled: August 15, 2002Date of Patent: April 4, 2006Assignee: Medtronic, Inc.Inventors: Peter Paul Zilla, Deon Bezuidenhout, Jacobus Petrus Theron
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Patent number: 6702848Abstract: A vascular prosthesis is constructed from a well-defined pore structure to allow uninterrupted ingrowth of connective tissue into a wall of the prosthesis. Several different methods can be used to produce the prosthesis, including a vacuum impregnation technique, a paste molding technique, a paste extrusion technique, a dip coating technique, and a melt extrusion technique. Furthermore, mechanical properties of the prosthesis are matched with mechanical properties of the host vessel, thereby overcoming problems of compliance mismatch.Type: GrantFiled: November 5, 1999Date of Patent: March 9, 2004Inventors: Peter Paul Zilla, Deon Bezuidenhout
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Publication number: 20040006383Abstract: A vascular prosthesis is constructed from a well-defined pore structure to allow uninterrupted ingrowth of connective tissue into a wall of the prosthesis. Several different methods can be used to produce the prosthesis, including a vacuum impregnation technique, a paste molding technique, a paste extrusion technique, a dip coating technique, and a melt extrusion technique. Furthermore, mechanical properties of the prosthesis are matched with mechanical properties of the host vessel, thereby overcoming problems of compliance mismatch.Type: ApplicationFiled: July 2, 2003Publication date: January 8, 2004Applicant: Medtronic, Inc.Inventors: Peter Paul Zilla, Deon Bezuidenhout
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Patent number: 6673108Abstract: A multilayer ingrowth matrix is constructed within well-defined porosity of a prosthetic material. The matrix consists of either proteinaceous or synthetic layers or gradients, or a combination of proteinaceous and synthetic layers or gradients. Each layer within the matrix is designed to achieve a specific function, such as facilitation of ingrowth of a particular cell type or release of a particular growth factor. The well-defined porosity is in the form of either helically oriented, interconnected transmural ingrowth channels, or a porous wall structure containing uniformly shaped pores (i.e. voids) in a very narrow size range, or a combination of channels and pores. This invention allows for uninterrupted ingrowth of connective tissue into walls of a synthetic graft prosthesis made from the prosthetic material. Furthermore, this invention can produce small diameter prostheses having an internal diameter of 6 mm or less.Type: GrantFiled: May 10, 2002Date of Patent: January 6, 2004Assignee: Medtronic, IncInventors: Peter Paul Zilla, Deon Bezuidenhout, Theresa Yvonne Dower
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Patent number: 6616699Abstract: A vascular prosthesis is constructed from a well-defined pore structure to allow uninterrupted ingrowth of connective tissue into a wall of the prosthesis. Several different methods can be used to produce the prosthesis, including a vacuum impregnation technique, a paste molding technique, a paste extrusion technique, a dip coating technique, and a melt extrusion technique. Furthermore, mechanical properties of the prosthesis are matched with mechanical properties of the host vessel, thereby overcoming problems of compliance mismatch.Type: GrantFiled: January 9, 2001Date of Patent: September 9, 2003Inventors: Peter Paul Zilla, Deon Bezuidenhout
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Patent number: 6554857Abstract: A multilayer ingrowth matrix is constructed within well-defined porosity of a prosthetic material. The matrix consists of either proteinaceous or synthetic layers or gradients, or a combination of proteinaceous and synthetic layers or gradients. Each layer within the matrix is designed to achieve a specific function, such as facilitation of ingrowth of a particular cell type or release of a particular growth factor. The well-defined porosity is in the form of either helically oriented, interconnected transmural ingrowth channels, or a porous wall structure containing uniformly shaped pores (i.e. voids) in a very narrow size range, or a combination of channels and pores. This invention allows for uninterrupted ingrowth of connective tissue into walls of a synthetic graft prosthesis made from the prosthetic material. Furthermore, this invention can produce small diameter prostheses having an internal diameter of 6 mm or less.Type: GrantFiled: November 5, 1999Date of Patent: April 29, 2003Assignee: Medtronic, INCInventors: Peter Paul Zilla, Deon Bezuidenhout, Theresa Yvonne Dower
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Patent number: 6540780Abstract: A vascular prosthesis is constructed from a structure having interconnected, helically oriented channel-porosity to allow oriented ingrowth of connective tissue into a wall of the prosthesis. The prosthesis can have a small internal diameter of 6 mm or less. Several different methods can be used to produce the prosthesis, including a fiber winding and extraction technique, a melt extrusion technique, and a particle and fiber extraction technique using either a layered method or a continuous method. Furthermore, mechanical properties of the prosthesis are matched with mechanical properties of the host vessel, thereby overcoming problems of compliance mismatch.Type: GrantFiled: November 5, 1999Date of Patent: April 1, 2003Assignee: Medtronic, Inc.Inventors: Peter Paul Zilla, Deon Bezuidenhout
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Publication number: 20030045927Abstract: A vascular graft prosthesis having ingrowth-permissive lumenal wall features with a thin film or layer of sealant-like material placed at a lumenal wall location to promote improved transmural tissue growth and healing.Type: ApplicationFiled: August 15, 2002Publication date: March 6, 2003Inventors: Peter Paul Zilla, Deon Bezuidenhout, Jacobus Petrus Theron
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Publication number: 20020169499Abstract: A vascular prosthesis is constructed from a structure having interconnected, helically oriented channel-porosity to allow oriented ingrowth of connective tissue into a wall of the prosthesis. The prosthesis can have a small internal diameter of 6 mm or less. Several different methods can be used to produce the prosthesis, including a fiber winding and extraction technique, a melt extrusion technique, and a particle and fiber extraction technique using either a layered method or a continuous method. Furthermore, mechanical properties of the prosthesis are matched with mechanical properties of the host vessel, thereby overcoming problems of compliance mismatch.Type: ApplicationFiled: July 2, 2002Publication date: November 14, 2002Applicant: Medtronic, Inc.Inventors: Peter Paul Zilla, Deon Bezuidenhout
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Publication number: 20020151968Abstract: A multilayer ingrowth matrix is constructed within well-defined porosity of a prosthetic material. The matrix consists of either proteinaceous or synthetic layers or gradients, or a combination of proteinaceous and synthetic layers or gradients. Each layer within the matrix is designed to achieve a specific function, such as facilitation of ingrowth of a particular cell type or release of a particular growth factor. The well-defined porosity is in the form of either helically oriented, interconnected transmural ingrowth channels, or a porous wall structure containing uniformly shaped pores (i.e. voids) in a very narrow size range, or a combination of channels and pores. This invention allows for uninterrupted ingrowth of connective tissue into walls of a synthetic graft prosthesis made from the prosthetic material. Furthermore, this invention can produce small diameter prostheses having an internal diameter of 6 mm or less.Type: ApplicationFiled: May 10, 2002Publication date: October 17, 2002Applicant: Medtronic, Inc.Inventors: Peter Paul Zilla, Deon Bezuidenhout, Theresa Yvonne Dower
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Publication number: 20010002444Abstract: A vascular prosthesis is constructed from a well-defined pore structure to allow uninterrupted ingrowth of connective tissue into a wall of the prosthesis. Several different methods can be used to produce the prosthesis, including a vacuum impregnation technique, a paste molding technique, a paste extrusion technique, a dip coating technique, and a melt extrusion technique. Furthermore, mechanical properties of the prosthesis are matched with mechanical properties of the host vessel, thereby overcoming problems of compliance mismatch.Type: ApplicationFiled: January 9, 2001Publication date: May 31, 2001Applicant: Medtronic, Inc.Inventors: Peter Paul Zilla, Deon Bezuidenhout