Patents by Inventor Peter Philip Gray

Peter Philip Gray has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of screening multiply transformed cells using bicistronic expression of fluorescent proteins
    Patent number: 7977097
    Abstract: A method of screening multiply transformed/transfected cells to identify those cells expressing at least two peptides or proteins of interest. The method comprising: 1. Simultaneously or sequentially transforming a cell with at least two different expression cassettes in which the gene of interest is linked via an IRES to a fluorescent marker gene. Each marker gene is different. 2. Providing conditions in which expression of the genes will occur. 3. Identifying cells expressing proteins by detecting the different fluorescent signals.
    Type: Grant
    Filed: November 24, 2000
    Date of Patent: July 12, 2011
    Assignee: The University of New South Wales
    Inventors: Robert D. Gay, Noelle-Anne Sunstrom, Peter Philip Gray
  • Regulated autocrine growth of mammalian cells
    Patent number: 6797515
    Abstract: Methods of production of desired recombinant proteins, polypeptides and peptides are disclosed which utilize mammalian host cells engineered for autonomous and regulated growth in low cost protein/serum-free culture media. Preferred host cells express insulin or an insulin-like growth factor, and/or transferrin and are engineered so that addition of an inducer (e.g., ZnCl2+CdCl2) halts growth and simultaneously induces the expression of the desired recombinant protein, polypeptide or peptide.
    Type: Grant
    Filed: September 28, 2001
    Date of Patent: September 28, 2004
    Assignees: Unisearch Limited, Commonwealth Scientific and Industrial Research Organisation
    Inventors: Sybille Marie Hunt, Peter Philip Gray, Merilyn Joy Sleigh
  • Regulated autocrine growth of mammalian cells
    Publication number: 20020102650
    Abstract: Methods of production of desired recombinant proteins, polypeptides and peptides are disclosed which utilize mammalian host cells engineered for autonomous and regulated growth in low cost protein/serum-free culture media. Preferred host cells express insulin or an insulin-like growth factor, and/or transferrin and are engineered so that addition of an inducer (e.g., ZnCl2+CdCl2) halts growth and simultaneously induces the expression of the desired recombinant protein, polypeptide or peptide.
    Type: Application
    Filed: September 28, 2001
    Publication date: August 1, 2002
    Inventors: Sybille Marie Hunt, Peter Philip Gray, Merilyn Joy Sleigh
  • Regulated autocrine growth of mammalian cells
    Patent number: 6340574
    Abstract: Methods of production of desired recombinant proteins, polypeptides and peptides are disclosed which utilize mammalian host cells engineered for autonomous and regulated growth in low cost protein/serum-free culture media. Preferred host cells express insulin or an insulin-like growth factor, and/or transferrin and are engineered so that addition of an inducer (e.g., ZnCl2+CdCl2) halts growth and simultaneously induces the expression of the desired recombinant protein, polypeptide or peptide.
    Type: Grant
    Filed: January 26, 1998
    Date of Patent: January 22, 2002
    Assignees: Unisearch Limited, Commonwealth Scientific and Industrial Research Organization
    Inventors: Sybille Marie Hunt, Peter Philip Gray, Merilyn Joy Sleigh