Patents by Inventor Peter Probst

Peter Probst has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240132589
    Abstract: The disclosure relates to LILRB2 antibody products and methods of use thereof. The antibody products specifically bind to LILRB2 on cells such as myeloid cells or cancer cells. The antibody products can be used in methods of treatment of disease, such as methods cancer immunotherapy.
    Type: Application
    Filed: October 17, 2023
    Publication date: April 25, 2024
    Inventors: Meghan Zuck, Peter Probst, Thomas J. Graddis, Myriam N. Bouchlaka Bay, Kamal D. Puri
  • Publication number: 20240101696
    Abstract: Provided herein are antibodies and methods of use thereof. The antibodies as disclosed herein bind to CD163+ on cells, such as on macrophages. These antibodies can be used in methods of treatment, such as methods of treating cancer.
    Type: Application
    Filed: March 17, 2023
    Publication date: March 28, 2024
    Inventors: Kamal D. Puri, Siddarth Chandrasekaran, Melissa L. Conerly, Peter Probst, Tyrel T. Smith, Mark E. Branum, Randi M. Simmons
  • Patent number: 11827715
    Abstract: Provided herein are antibodies and methods of use thereof. The antibodies as disclosed herein bind to CD163+ on cells, such as on macrophages. These antibodies can be used in methods of treatment, such as methods of treating cancer.
    Type: Grant
    Filed: April 22, 2021
    Date of Patent: November 28, 2023
    Assignee: OncoResponse, Inc.
    Inventors: Kamal D. Puri, Siddarth Chandrasekaran, Melissa L. Conerly, Randi M. Simmons, Tyrel T. Smith, Mark E. Branum, Peter Probst
  • Publication number: 20230251156
    Abstract: The present disclosure relates to a piston diaphragm seal for transmitting a pressure of a medium to a pressure-measuring sensor a base body having a recess and a bore which is connected to the recess. The recess and the bore can be filled with a pressure transfer medium. A piston is arranged in the recess and can be moved within a predetermined region in the recess. A surface of the piston facing the medium can be loaded with the pressure of the medium, wherein the piston is separated by at least two sealing elements from the medium and the pressure transfer medium. A cavity is arranged in the piston between the at least two sealing elements. An attachment region is provided for connecting the piston diaphragm seal to the pressure-measuring sensor. A monitoring unit is designed to determine and/or monitor entry of medium and/or pressure transfer medium into the cavity.
    Type: Application
    Filed: February 6, 2023
    Publication date: August 10, 2023
    Inventors: Dietmar Leuthner, Klaus Behrendt, Jacobo Carrasco Heres, Peter Probst, Alfred Schmelzle
  • Publication number: 20230181732
    Abstract: Provided herein are uses of antibodies that bind to CD163 expressed on a human myeloid cell in combination with checkpoint inhibitors. Among other things, these CD163 antibodies can be used with checkpoint inhibitors in methods of treatment of humans, such as methods of treating a cancer or methods of relieving T cell suppression.
    Type: Application
    Filed: September 2, 2022
    Publication date: June 15, 2023
    Inventors: Siddarth Chandrasekaran, Tyrel T. Smith, Kamal D. Puri, Randi M. Simmons, Peter Probst, Robert J. Lechleider
  • Patent number: 11634501
    Abstract: Provided herein are antibodies and methods of use thereof. The antibodies as disclosed herein bind to CD163+ on cells, such as on macrophages. These antibodies can be used in methods of treatment, such as methods of treating cancer.
    Type: Grant
    Filed: July 17, 2020
    Date of Patent: April 25, 2023
    Assignee: OncoResponse, Inc.
    Inventors: Kamal D. Puri, Siddarth Chandrasekaran, Melissa L. Conerly, Peter Probst, Tyrel T. Smith, Mark E. Branum, Randi M. Simmons
  • Publication number: 20220289861
    Abstract: Provided herein are antibodies and methods of use thereof. The antibodies as disclosed herein bind to CD163+ on cells, such as on macrophages. These antibodies can be used in methods of treatment, such as methods of treating cancer.
    Type: Application
    Filed: July 17, 2020
    Publication date: September 15, 2022
    Inventors: Kamal D. Puri, Siddarth Chandrasekaran, Melissa L. Conerly, Peter Probst, Tyrel T. Smith, Mark E. Branum, Randi M. Simmons
  • Publication number: 20210253733
    Abstract: Provided herein are antibodies and methods of use thereof. The antibodies as disclosed herein bind to CD163+ on cells, such as on macrophages. These antibodies can be used in methods of treatment, such as methods of treating cancer.
    Type: Application
    Filed: April 22, 2021
    Publication date: August 19, 2021
    Inventors: Kamal D. PURI, Siddarth Chandrasekaran, Melissa L. Conerly, Randi M. Simmons, Tyrel T. Smith, Mark E. Branum, Peter Probst
  • Patent number: 11034770
    Abstract: Provided herein are antibodies and methods of use thereof. The antibodies as disclosed herein bind to CD163+ on cells, such as on macrophages. These antibodies can be used in methods of treatment, such as methods of treating cancer.
    Type: Grant
    Filed: July 22, 2020
    Date of Patent: June 15, 2021
    Assignee: OncoResponse, Inc.
    Inventors: Kamal D. Puri, Siddarth Chandrasekaran, Melissa L. Conerly, Randi M. Simmons, Tyrel T. Smith, Mark E. Branum, Peter Probst
  • Publication number: 20210047424
    Abstract: Provided herein are antibodies and methods of use thereof. The antibodies as disclosed herein bind to CD163+ on cells, such as on macrophages. These antibodies can be used in methods of treatment, such as methods of treating cancer.
    Type: Application
    Filed: July 22, 2020
    Publication date: February 18, 2021
    Inventors: Kamal D. PURI, Siddarth CHANDRASEKARAN, Melissa L. CONERLY, Randi M. SIMMONS, Tyrel T. SMITH, Mark E. BRANUM, Peter PROBST
  • Publication number: 20200071316
    Abstract: The present invention is directed to compounds of Formula (I), which are activators of the RIG-I pathway.
    Type: Application
    Filed: August 9, 2019
    Publication date: March 5, 2020
    Inventors: Daniel R. Goldberg, Peter Probst, Kristin M. Bedard
  • Publication number: 20200055871
    Abstract: The present invention is directed to compounds of Formula (I), which are activators of the RIG-I pathway.
    Type: Application
    Filed: August 9, 2019
    Publication date: February 20, 2020
    Inventors: Daniel R. Goldberg, Peter Probst, Kristin M. Bedard
  • Patent number: 9114729
    Abstract: A seat rail for a vehicle seat of a motor vehicle, including a seat rail profiled element, which has at least one profile region into which at least one corresponding retaining element of the vehicle seat can be inserted in at least one retaining position. The seat rail includes at least one ramp element extending at an angle from the longitudinal extension of the seat rail profiled element, by which ramp element the retaining element can be moved out of the profile region from the retaining position to at least one removal position by moving the retaining element along the ramp element.
    Type: Grant
    Filed: November 12, 2011
    Date of Patent: August 25, 2015
    Assignee: KEIPER GMBH & CO. KG
    Inventors: Andreas Kinzer, Joachim Mühlberger, Jürgen Nasshan, Peter Probst, Boris Willems
  • Publication number: 20140292018
    Abstract: A seat rail for a vehicle seat of a motor vehicle, including a seat rail profiled element, which has at least one profile region into which at least one corresponding retaining element of the vehicle seat can be inserted in at least one retaining position. The seat rail includes at least one ramp element extending at an angle from the longitudinal extension of the seat rail profiled element, by which ramp element the retaining element can be moved out of the profile region from the retaining position to at least one removal position by moving the retaining element along the ramp element.
    Type: Application
    Filed: November 12, 2011
    Publication date: October 2, 2014
    Inventors: Andreas Kinzer, Joachim Mühlberger, Jürgen Nasshan, Peter Probst, Boris Willems
  • Patent number: 8683261
    Abstract: Instructions within a processor are managed by receiving, at a recovery unit of the processor, an instruction that modifies a control register residing within the recovery unit. The recovery unit receives a first set of data associated with the instruction from a general register. A second set of data associated with the instruction is retrieved from the control register by the recovery unit. The recovery unit performs at least one binary logic operation on the first set of data and the second data.
    Type: Grant
    Filed: July 20, 2011
    Date of Patent: March 25, 2014
    Assignee: International Business Machines Corporation
    Inventors: Michael Cremer, Guenter Gerwig, Frank Lehnert, Peter Probst
  • Publication number: 20140056967
    Abstract: The present invention relates to compositions comprising proteins or polynucleotides of Chlamydia sp., in particular combinations of proteins or polynucleotides encoding them, and methods for the use of the proteins or polynucleotides in the treatment, prevention and diagnosis of Chlamydia infection.
    Type: Application
    Filed: August 13, 2013
    Publication date: February 27, 2014
    Applicants: GlaxoSmithKline Biologicals S.A., Corixa Corporation
    Inventors: Brenda Barth, India Ajay, Mark Alderson, Jean-Francois L. Maisonneuve, Yves Lobert, Florence Bernadette Nozay, Martine Marchand, Pascal Mettens, Yasir A. Skeiky, Peter Probst
  • Patent number: 8541007
    Abstract: The present invention relates to compositions comprising proteins or polynucleotides of Chlamydia sp., in particular combinations of proteins or polynucleotides encoding them, and methods for the use of the proteins or polynucleotides in the treatment, prevention and diagnosis of Chlamydia infection.
    Type: Grant
    Filed: December 21, 2010
    Date of Patent: September 24, 2013
    Assignees: GlaxoSmithKline Biologicals S.A., Corixa Corporation
    Inventors: Mark Alderson, Ajay Bhatia, Yves Lobet, Brenda Maisonneuve, Jean-Francois L Maisonneuve, Martine Marchand, Pascal Mettens, Florence Bernadette Nozay, Peter Probst, Samira H Skeiky
  • Patent number: 8377448
    Abstract: Provide herein are fusion polypeptides that comprise a CD47 extracellular domain or a variant thereof that is fused to a Fc polypeptide. The fusion polypeptides are useful for treating an immunological disease or disorder in a subject according to the methods described herein. The fusion polypeptides are capable of suppressing immunoresponsiveness of an immune cell, inhibiting production of proinflammatory cytokines, including inhibiting immune complex-induced production of cytokines.
    Type: Grant
    Filed: January 14, 2010
    Date of Patent: February 19, 2013
    Assignee: The Board of Trustees of the Leland Standford Junior University
    Inventors: Craig A. Smith, Steven Wiley, Ajamete Kaykas, Peter Probst
  • Publication number: 20130024725
    Abstract: Instructions within a processor are managed by receiving, at a recovery unit of the processor, an instruction that modifies a control register residing within the recovery unit. The recovery unit receives a first set of data associated with the instruction from a general register. A second set of data associated with the instruction is retrieved from the control register by the recovery unit. The recovery unit performs at least one binary logic operation on the first set of data and the second data.
    Type: Application
    Filed: July 20, 2011
    Publication date: January 24, 2013
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Michael CREMER, Guenter GERWIG, Frank LEHNERT, Peter PROBST
  • Patent number: 8263089
    Abstract: Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: September 11, 2012
    Assignee: Corixa Corporation
    Inventors: Ajay Bhatia, Yasir A. W. Skeiky, Peter Probst