Abstract: Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.

Abstract: Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems; and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.

Abstract: Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.

Abstract: Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.

Abstract: Intravenous, or indwelling, or integratedmulti-functional devices and systems reduce levels of a targeted compound in blood by selective adsorption. The devices and systems can be used, e.g., to reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices and systems are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices and systems serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.

Abstract: Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.

Abstract: Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.

Abstract: Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in physiologic fluid by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.

Abstract: A hemo- and biocompatible polymeric adsorbing material for purification of physiological fluids of organism has a plurality of beads each having a generally hydrophobic core provided with a plurality of pores, and a hydrophilic hemo- and biocompatible coating which coats at least a part of a surface of the core, wherein a thickness of the hemo- and biocompatible coating is selected between about 20 angstrom and about 1 micron. A method of producing the material includes the new coating of the surface of the core. A device for and a method of purification of physiological fluids of organism includes the use of the new material.

Abstract: For sieving biocompatible adsorbent beaded polymeric materials a column is filled with beads, a fluid is supplied into the column upwardly, a screening element located in the column between a bottom of the column and a top of the column so that beads below a predetermined threshold are displaced by the fluid flowing upwardly and through the screening element, while beads above the predetermined threshold are retained under the screening element, and another fluid is supplied downwardly so as to prevent clogging of said screening element and to agitate the polymeric beads in the column under the screening element.

Abstract: A hemo- and biocompatible polymeric adsorbing material for purification of physiological fluids of an organism has a plurality of beads, each having a core having hydrophobic properties and a plurality of pores, and a coating having a hydrophilic, hemo- and bicompatible property applied on a surface of the core and occupying about 20%-90% of the surface of the core so as to form on the surface of the core alternating portions of the hydrophilic hemo- and biocompatible coating and portions of hydrophobic core which are not covered with the coating. A method of producing the material includes the selective coating of the surface of the core. A device for and a method of purification of physiological fluids of organism includes the use of the new material.

Abstract: For sieving biocompatible adsorbent beaded polymeric materials, a column is formed for accommodating beads of the polymeric material, a fluid is formed into the column upwardly, a plurality of screening elements located in the column between a bottom of the column and a top of the column and spaced from one another in a vertical direction, the screening elements having openings of different sizes, so that beads of the polymeric material below a predetermined threshold are displaced by a fluid flowing upwardly and through a respect to one of the screening elements, while beads above the predetermined threshold are retained under a respective one of the screening elements, and a plurality of further fluids are supplied downwardly onto each of the screening elements so as to prevent clogging of a respective one of the screening elements and to agitate the polymeric beads in the column under a respective one of the screening elements.

Abstract: A device for preventing infections during introduction of a fluid into a body, has an element which is formed so as to surround an introducer over its periphery and extend over a part of its elongation, so that when the introducer is introduced through an opening into the body the element completely covers an area of the opening, the element being composed of a material which is biocompatible and does not cause growth of germs, bacteria, and the like.