Abstract: Disclosed are monoclonal antibodies, antigen binding fragments, and bi-specific antibodies that specifically bind a coronavirus spike protein, such as SARS-CoV-2. Also disclosed is the use of these antibodies for inhibiting a coronavirus infection, such as a SARS-CoV-2 infection. In addition, disclosed are methods for detecting a coronavirus, such as SARS-CoV-2, in a biological sample, using the disclosed antibodies.

Abstract: Position detecting apparatus having a target comprising radiation emitting eans for emitting radiation to define four points in non-planar relationship such that a first set of three of the points lies in a first target plane while a second set of three of the points lies in a second target plane which may for example be substantially normal to the first target plane; a camera having a focal plane on which images of objects presented to the camera are formed, the camera being arranged for viewing said target, and being provided at said focal plane with a two-dimensional array of photo sensitive elements which can receive radiation from the radiation emitting means of the said target; and a computer arranged to scan said two dimensional array to generate signals indicative of the position of images of the radiation emitting means on the array, whereby the position of the target, and hence of an object to which it is attached, may be determined in relation to a selected reference plane.