Abstract: A method for treating an occlusion comprises positioning a catheter at a treatment site in a patient's vasculature. A blockage is located at the treatment site. The method further comprises performing a medical treatment at the treatment site. The medical treatment is configured to reduce the blockage. The method further comprises making a plurality of measurements at the treatment site.

Abstract: An infusion device having a housing with a reusable control portion and an expendable reservoir portion includes a precise drive for an infusion pump. The drive includes a piezoelectric bender assembly, a limiter and at least one contact stop. The piezoelectric bender assembly includes a cantilevered piezoelectric bender having an member of predetermined thickness fixed to move with the second end. A limiter of dimensionally stable material including a gap and at least a first mounting hole extending to the gap. The member of predetermined thickness extends into the gap. A first contact stop is positioned in the gap to define a critical gap distance limiting movement of the member of predetermined thickness in the gap. A base has a mounting surface, a port through the base and extending to the mounting surface. The port includes a first length having a smaller diameter at the mounting surface and a second length displaced from the mounting surface and having a larger diameter.

Abstract: A system for infusing liquid to a body includes an infusion device, a network interface with a cell phone and wireless link and a network server system capable of communication with the infusion device through the network interface. The server system has access to a file of information specific to the controller for the infusion device. The infusion device includes a source of infusion fluid, a delivery port, a pump between the source of infusion fluid and the delivery port and a controller capable of programmable pump rate and sequence. A method for infusing liquid to a body includes controlling infusion using a programmable controller, establishing a file of information specific to the controller accessible to an extended area network server system and remotely transmitting commands to the controller. The information specific to the controller in the file is amended from a control terminal remote from the body.

Abstract: A central venous catheter comprises an ultrasound assembly. In one arrangement, the radiating member is used to remove a blockage from the central venous catheter. In another arrangement, inserting an ultrasound assembly into a central venous catheter. The ultrasound assembly comprises an ultrasound radiating member mounted on an elongate support structure. The method further comprises positioning the ultrasound assembly within the central venous catheter such that the ultrasound radiating member is adjacent to a deposited material formed on a portion of the central venous catheter. The method further comprises supplying an electrical current to the ultrasound radiating member to expose the deposited material to ultrasonic energy. The method further comprises passing a therapeutic compound through the central venous catheter to expose the deposited material to the therapeutic compound simultaneously with ultrasonic energy.

Abstract: An infusion device having a housing with a reusable control portion and an expendable reservoir portion includes a precise drive for an infusion pump. The drive includes a piezoelectric bender assembly, a limiter and at least one contact stop. The piezoelectric bender assembly includes a cantilevered piezoelectric bender having an member of predetermined thickness fixed to move with the second end. A limiter of dimensionally stable material including a gap and at least a first mounting hole extending to the gap. The member of predetermined thickness extends into the gap. A first contact stop is positioned in the gap to define a critical gap distance limiting movement of the member of predetermined thickness in the gap. A base has a mounting surface, a port through the base and extending to the mounting surface. The port includes a first length having a smaller diameter at the mounting surface and a second length displaced from the mounting surface and having a larger diameter.

Abstract: A system for infusing liquid to a body includes an infusion device, a network interface with a cell phone and wireless link and a network server system capable of communication with the infusion device through the network interface. The server system has access to a file of information specific to the controller for the infusion device. The infusion device includes a source of infusion fluid, a delivery port, a pump between the source of infusion fluid and the delivery port and a controller capable of programmable pump rate and sequence. A method for infusing liquid to a body includes controlling infusion using a programmable controller, establishing a file of information specific to the controller accessible to an extended area network server system and remotely transmitting commands to the controller. The information specific to the controller in the file is amended from a control terminal remote from the body.

Abstract: A method for providing a therapeutic effect to a treatment site within a patient's vasculature comprises positioning a catheter at the treatment site. The catheter includes a heating element and a fluid delivery lumen that is coupled to an exit port within a distal region of the catheter. The method further comprises passing the therapeutic compound through the delivery lumen and the exit port at a flow rate. The heated therapeutic compound is provided to the treatment site. The method further comprises exposing at least a portion of the treatment site and at least a portion of the delivered heated therapeutic compound to ultrasonic energy generated by the ultrasound radiating member.