Abstract: Disclosed are various embodiments of permanent active sensors in a tire achieved by partially embedding a sensor component in a green tire and adding a removable power source after the tire is cured. The printed circuit board can be encapsulated in the rubber of the tire with a power source housing connected to the electronics through the rubber. In another aspect, the printed circuit board can be directly connected to the power source housing. The sensor interlocks with the rubber of the tire. Various structural features of the sensor, such as a flange or channels for the rubber, can be used to secure the sensor in the rubber of the tire.

Abstract: The invention relates to a pneumatic tool with a handle (26), valve (22), a safety switch lever (18) arranged on the handle (26) for actuating the valve (22) and a pressure medium connection (16), wherein the valve (22) comprises a valve body (28) movable between a home position and at least one further position, wherein a connection between the pressure medium connection (16) and a pressure cylinder (12) of the tool is interrupted in the home position and the connection between the pressure medium connection (16) and the pressure cylinder (12) of the tool is established in the further position. It is proposed that the pressure cylinder (12) is vented with the displacement of the valve body (28) to the home position and a pressure applied to the pressure medium connection (16) displaces the valve body (28) toward the home position when the safety switch lever (18) is released.

Abstract: This disclosure provides modulators of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) having core structure (I), pharmaceutical compositions containing at least one such modulator, methods of treatment of CFTR mediated diseases, including cystic fibrosis, using such modulators and pharmaceutical compositions, combination pharmaceutical compositions and combination therapies employing those modulators, and processes and intermediates for making such modulators.

Abstract: In various embodiments, an energy storage mounting system includes an inverter wall bracket mounted to a wall, wherein an inverter is coupled to the inverter wall bracket. The system includes a battery wall bracket to which a battery block is coupled. The battery wall bracket interfaces with an auxiliary bracket that is mounted to the wall, is vertically translatable relative to the auxiliary bracket, and is at least in part ground-supported. The battery block is electrically connected to the inverter.

Abstract: The invention relates to a breathing assistance apparatus that may be configured to reduce the risk of damage to electronics within the apparatus as a result of liquid leaks within the apparatus or impacts to the apparatus. In other forms, the apparatus may be configured to allow for easy assembly and/or safe operation.

Abstract: Electrophoresis is used to identify presence of a target compound in a patient sample based on a charge state of the compound and a label. The charge state of the compound correlates to a total net charge of a binder conjugated to the compound. The bound complex or “bound complex” with the label is then applied to the electrophoresis substrate. An electric potential is applied to the substrate for a time period and causes the labeled bound complex to migrate toward the electrode with opposite charge of the labeled bound complex at a migration velocity to form a migration pattern over the time period. At some time during or at the end of the time period, the labeled bound complex produces a bound complex band as a result of its migration across the substrate. The presence of the compound is identified based on the labeled bound complex band and one or both of the migration pattern and the migration velocity.

Abstract: A fluid cooled mold plate is disclosed. The fluid cooled mold plate has a front side, a rear side, and a perimeter that extends between its front and rear sides. A cooling chamber is formed within the mold plate. The cooling chamber has a front wall, a rear wall, and a perimeter wall that extends between the front and rear walls. An inlet fluid duct extends from a first side of the mold plate perimeter to a first end of the cooling chamber and an outlet fluid duct extends from a second side of the mold plate perimeter to a second end of the cooling chamber. The cooling chamber is occupied by a turbulence generating dispersion mesh that is secured between the front and rear walls the cooling chamber.

Abstract: A device (102) provides respiratory treatment for SDB (including mild OSA) and other respiratory conditions. A flow generator warms and humidifies gas at controlled flow levels. For example, the device (102) delivers breathable gas to the upper airway at flow rates of about 10-35 Liters/minute. Levels of flow rate, temperature and/or humidification of the device may be automatically adjusted in response to the detection of SDB events. The device may also automatically deliver adjustments of any of the levels in accordance with detected phases of respiratory cycles. In some embodiments, the device automatically delivers distinct levels to either of the nares based on independent control of flow to each nare. A warm-up procedure controls temperature and humidity at a desired target during a ramp-up of flow to the set therapy level. A cool-down procedure controls temperature above the dewpoint to avoid condensation internal to the device and patient interface.

Abstract: A wiring harness for a battery and inverter system includes a main cable. It further includes an inverter connector configured to plug the main cable into an inverter module. It further includes a first spur of the main cable terminating in a first-type battery device connector. It further includes a second spur of the main cable terminating in a second type battery device connector.

Abstract: A cover is disclosed, including: a first gasket that is placed along a portion of the cover that is to join with a heat sink; a second gasket that is placed around a cutout region of the cover, wherein the cover is configured to couple to a circuit board associated with the power module and expose a component on the circuit board through the cutout region; and a fastener that is configured to engage with the heat sink.

Abstract: In various embodiments, an energy storage mounting system includes an inverter wall bracket mounted to a wall, wherein an inverter is coupled to the inverter wall bracket. The system includes a battery wall bracket to which a battery block is coupled. The battery wall bracket interfaces with an auxiliary bracket that is mounted to the wall, is vertically translatable relative to the auxiliary bracket, and is at least in part ground-supported. The battery block is electrically connected to the inverter.

Abstract: A vacuum cleaner with a battery unit for powering the vacuum cleaner is provided. The battery unit includes a plurality of serially connected battery cells and battery management electronics operatively coupled to the battery cells. Two enclosures are provided on either side of a central axis of the vacuum cleaner, each enclosure including a portion of the plurality of battery cells, and a portion of the battery management electronics operatively coupled to the respective portion of the plurality of the battery cells. A link strap interconnects the portions of the battery management electronics.

Abstract: A vacuum system, including a condenser including a first inlet, a first outlet, and a second outlet, a first ejector connected to a motive fluid source, and a second ejector connected to the motive fluid source and the condenser.

Abstract: Methods and apparatus for manufacturing a microfluidic arrangement are disclosed. In one arrangement, a continuous body of a first liquid is provided in direct contact with a first substrate. A second liquid covers the first liquid. A separation fluid, immiscible with the first liquid, is propelled through at least the first liquid and into contact with the first substrate along all of a selected path on the surface of the first substrate. First liquid that was initially in contact with all of the selected path is displaced away from the selected path. The first liquid is divided to form sub-bodies of first liquid that are separated from each other. For each of one or more of the sub-bodies, a sub-body footprint represents an area of contact between the sub-body and the first substrate, and all of a boundary of the sub-body footprint is in contact with a closed loop of the selected path surrounding the sub-body footprint.

Abstract: Precision digital chronography based on detected changes in state of a processor is described. The changes in state may be detected by another processor and an averaged time interval generated. A signal corresponding to the averaged time interval may be communicated to a distributed database and propagated to remote systems. Devices associated with the remote systems may adjust or set a device clock in accordance with the averaged time interval.

Abstract: Systems and methods include a wearable device with an electrically conductive skin interface that excites the underlying nerves from a transcutaneous surface stimulator. The device may be sized for a range of user sizes with stimulation electrodes positioned to target the appropriate nerves, such as the saphenous and/or posterior tibial nerves. The therapy may be adjusted based on leg restlessness or movement.

Abstract: Presenting ancestral origin information, comprising: receiving a request to display ancestry data of an individual; obtaining ancestry composition information of the individual, the ancestry composition information including information pertaining to a proportion of the individual's genotype data that is deemed to correspond to a specific ancestry; and presenting the ancestry composition information to be displayed.

Abstract: A fluid cooled mold plate is disclosed. The fluid cooled mold plate has a front side, a rear side, and a perimeter that extends between its front and rear sides. A cooling chamber is formed within the mold plate. The cooling chamber has a front wall, a rear wall, and a perimeter wall that extends between the front and rear walls. An inlet fluid duct extends from a first side of the mold plate perimeter to a first end of the cooling chamber and an outlet fluid duct extends from a second side of the mold plate perimeter to a second end of the cooling chamber. The cooling chamber is occupied by a turbulence generating dispersion mesh that is secured between the front and rear walls the cooling chamber.

Abstract: A projectile for piercing a casing of a mine containing an explosive material. The projectile includes a projectile body having a nose portion and a tail portion and a longitudinal axis, a switch, and electrodes separated such that in use an electrical discharge can flow between them through an explosive material contained within a mine, or to initiate an energetic material provided between the electrodes to detonate an explosive material contained within a mine. Also provided is a method of mine disposal.

Abstract: Projectile launch apparatus (20) for use in a fluid environment. The apparatus (20) comprises a launch tube (21) having a supercavitating projectile (24) with cavitator (29) received within the launch tube (21). A means for generating expulsion gas (not visible) is arranged to provide expulsion gas to propel the projectile (24) from the launch tube (21), with means for bleeding expulsion gas (31, 32) being provided to bleed a portion of expulsion gas around the projectile (24). This allows expulsion gases to contribute to the formation of the gas cavity around the supercavitating projectile (24) as the projectile (24) is launched from the launch tube (21). Particularly suited to the deployment of supercavitating projectiles underwater, such as in underwater mine disposal applications.