Abstract: A cushioned in-line skate shoe comprises: an in-line skate shoe body, including: an outer side wall which has an outer lower edge, an inner side wall which has an inner lower edge, a sole provided on a bottom of the shoe body and connected between the outer and inner lower edges, at least one outer hole and at least one inner hole formed on the outer lower edge and the inner lower edge, respectively; an air cushion foot pad including: an upper surface, a lower surface opposing to the upper surface, a circumferential edge which is formed between the upper and lower surfaces, a plurality of flexible columns connecting the upper surface and the lower surface to define a plurality of air chambers formed within the circumferential edge so as to rigidly support the air chambers, a plurality of transverse protrusions formed on the circumferential edge of the foot pad, thereby when the foot pad is positioned over and contact with the sole of the shoe body, the protrusions are inserted into the outer and inner holes o