Abstract: The present invention relates to a biocompatible device which comprises on its surface an adsorbed layer of a polymer P which is a copolymer of at least one macromonomer selected from an ester E of (meth)acrylic acid and polyethylene oxide or a polyethylene glycol (meth)acrylamide, at least one monomer M selected from alkyl (meth)acrylate, aryloxyalkyl (meth)acrylate, alkyl (meth)acrylamide or aryl (meth)acrylamide, and at least one cationic monomer C selected from cationic ethylenically unsaturated N-containing monomers. It further relates to a process for making a biocompatible device which comprises on its surface an adsorbed layer of the polymer P comprising the following steps: providing a biocompatible device, and applying to the surface of the biocompatible device a solution S of the polymer Pin a solvent L.

Abstract: Biosensor BS comprising at least one polymer P wherein said polymer P is a copolymer of at least monomer M and at least one ester E of (meth)acrylic acid and polyethylene oxide, wherein said monomer M is different from ester E and has at least one ethylenically unsaturated double bond, wherein polymer P has a surface adsorption SA of at least 200 ng/cm2 on the respective surface where polymer P is deposited, said SA being determined by quartz crystal microbalance.

Abstract: Process for reducing the fouling of a surface O, wherein an aqueous solution S of at least one polymer P comprising styrene and at least one ester E of (meth)acrylic acid and polyethylene oxide in a molar ratio of 0.05:1 to 50:1 is applied to said surface O.

Abstract: Process for reducing the fouling of a surface O, wherein an aqueous solution S of at least one polymer P comprising styrene and at least one ester E of (meth)acrylic acid and polyethylene oxide in a molar ratio of 0.05:1 to 50:1 is applied to said surface O.

Abstract: The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula: A-L-CR where CR is a cyclical core group, L is a linking group and A is as defined herein. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.

Abstract: With the objective of improving an energy storage device comprising a transducer unit and a capacitor module which interacts with the transducer unit so it can be inserted as a physical device into a motor vehicle in particular, it is proposed to provide a housing to accommodate the capacitor cells of the capacitor module, for the housing to comprise a capacitor chamber accommodating the capacitor cells, and for the capacitor chamber to have a gas-tight seal.

Abstract: The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula: A-L-CR where CR is a cyclical core group, L is a linking group and A is as defined herein. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.

Abstract: The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula: A-L-CR where CR is a cyclical core group, L is a linking group and A is as defined herein. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.

Abstract: The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula: A-L-CR where CR is a cyclical core group, L is a linking group and A is as defined herein. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.

Abstract: With the objective of improving an energy storage device comprising a transducer unit and a capacitor module which interacts with the transducer unit so it can be inserted as a physical device into a motor vehicle in particular, it is proposed to provide a housing to accommodate the capacitor cells of the capacitor module, for the housing to comprise a capacitor chamber accommodating the capacitor cells, and for the capacitor chamber to have a gas-tight seal.

Abstract: A compound of the formula: is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.

Abstract: Compounds having the formula Ia or Ib wherein R1, R2, R3 and R4 are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.

Abstract: Compounds having the formula I wherein A, m and R1 are herein defined are Hepatitis C virus NS5b polymerase inhibitors.

Abstract: A flat panel workstation system that may be retrofitted into an existing desktop/work surface for supporting and pivoting a flat panel display such as a liquid crystal display (LCD) from a closed position to an open, viewable position in front of a user. The system includes a sliding keyboard and mouse platform mounted underneath the front edge of the desk top/work surface and which automatically pivot a support panel atop the work surface (and attached flat panel display) to an upright position or closed flush position upon extension/retraction of the keyboard and mouse platform.

Abstract: A computer workstation having a desktop/work surface defined by a central aperture and a pivoting liquid crystal display (LCD) support panel mounted on pivot shafts in the aperture. In addition, a sliding input device platform is mounted on telescoping roller brackets underneath the front edge of the work surface. Lever arms are rotatably engaged with the pivot shafts and are linked to the roller brackets. The lever arms automatically pivot the LCD support panel to an upright position upon extension of the input device platform, and vice versa, and a hydraulic damper brings the LCD support panel to a safe, gentle stop. Aa mercury switch turns the LCD on and off automatically upon opening or closing. Two or more such LCD support panels and associated hardware can be included in a single desktop/work surface for a computer training and/or conferences.

Abstract: A computer workstation having a desktop/work surface defined by a central aperture and a pivoting liquid crystal display (LCD) support panel mounted on pivot shafts in the aperture. In addition, a sliding input device platform is mounted on telescoping roller brackets underneath the front edge of the work surface. Lever arms are rotatably engaged with the pivot shafts and are linked to the roller brackets. The lever arms automatically pivot the LCD support panel to an upright position upon extension of the input device platform, and vice versa, and a hydraulic damper brings the LCD support panel to a safe, gentle stop. Aa mercury switch turns the LCD on and off automatically upon opening or closing. Two or more such LCD support panels and associated hardware can be included in a single desktop/work surface for a computer training and/or conferences.

Abstract: Compounds having the formula I wherein A, m and R1 are herein defined are Hepatitis C virus polymerase inhibitors. Also disclosed are compositions and methods for treating diseases mediated by HCV and for inhibiting hepatitis replication.

Abstract: The embodiments provide compounds of the general formulas I-XIX, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating flaviviral infection, including hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.

Abstract: A flat panel workstation system that may be retrofitted into an existing desktop/work surface for supporting and pivoting a flat panel display such as a liquid crystal display (LCD) from a closed position to an open, viewable position in front of a user. The system includes a sliding keyboard and mouse platform mounted underneath the front edge of the desk top/work surface and which automatically pivot a support panel atop the work surface (and attached flat panel display) to an upright position or closed flush position upon extension/retraction of the keyboard and mouse platform.