Patents by Inventor Peter T. Beernink

Peter T. Beernink has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Factor H Binding Protein Variants and Methods of Use Thereof
    Publication number: 20240101610
    Abstract: Variant factor H binding proteins that can elicit antibodies that are bactericidal for at least one strain of Neisseria meningitidis, compositions comprising such proteins, and methods of use of such proteins, are provided.
    Type: Application
    Filed: October 24, 2023
    Publication date: March 28, 2024
    Inventor: Peter T. BEERNINK
  • NEISSERIAL SURFACE PROTEIN A (NSPA) VARIANTS AND METHODS OF USE THEREOF
    Publication number: 20240024450
    Abstract: Variant Neisserial surface protein A (NspA) with reduced binding to human factor H (FH) are provided. These variants are useful for eliciting antibodies that are bactericidal for at least one strain of N. meningitidis. Compositions comprising such proteins, and methods of use of such proteins are disclosed.
    Type: Application
    Filed: August 6, 2021
    Publication date: January 25, 2024
    Inventors: Peter T. Beernink, Dhaarini Raghunathan
  • Factor H Binding Protein Variants and Methods of Use Thereof
    Publication number: 20240025951
    Abstract: Variant factor H binding proteins that can elicit antibodies that are bactericidal for at least one strain of Neisseria meningitidis, compositions comprising such proteins, and methods of use of such proteins, are provided.
    Type: Application
    Filed: May 12, 2023
    Publication date: January 25, 2024
    Inventor: Peter T. Beernink
  • Factor H binding protein variants and methods of use thereof
    Patent number: 11834476
    Abstract: Variant factor H binding proteins that can elicit antibodies that are bactericidal for at least one strain of Neisseria meningitidis, compositions comprising such proteins, and methods of use of such proteins, are provided.
    Type: Grant
    Filed: October 7, 2020
    Date of Patent: December 5, 2023
    Assignee: Children's Hospital & Research Center at Oakland
    Inventor: Peter T. Beernink
  • Factor H binding protein variants and methods of use thereof
    Patent number: 11673920
    Abstract: Variant factor H binding proteins that can elicit antibodies that are bactericidal for at least one strain of Neisseria meningitidis, compositions comprising such proteins, and methods of use of such proteins, are provided.
    Type: Grant
    Filed: April 2, 2021
    Date of Patent: June 13, 2023
    Assignee: Children's Hospital & Research Center at Oakland
    Inventor: Peter T. Beernink
  • FACTOR H BINDING PROTEIN VARIANTS AND METHODS OF USE THEREOF
    Publication number: 20210340191
    Abstract: Variant factor H binding proteins that can elicit antibodies that are bactericidal for at least one strain of Neisseria meningitidis, compositions comprising such proteins, and methods of use of such proteins, are provided.
    Type: Application
    Filed: April 2, 2021
    Publication date: November 4, 2021
    Inventor: Peter T. BEERNINK
  • Factor H binding protein variants and methods of use thereof
    Patent number: 10995122
    Abstract: Variant factor H binding proteins that can elicit antibodies that are bactericidal for at least one strain of Neisseria meningitidis, compositions comprising such proteins, and methods of use of such proteins, are provided.
    Type: Grant
    Filed: October 11, 2019
    Date of Patent: May 4, 2021
    Assignee: Children's Hospital & Research Center at Oakland
    Inventor: Peter T. Beernink
  • FACTOR H BINDING PROTEIN VARIANTS AND METHODS OF USE THEREOF
    Publication number: 20210101942
    Abstract: Variant factor H binding proteins that can elicit antibodies that are bactericidal for at least one strain of Neisseria meningitidis, compositions comprising such proteins, and methods of use of such proteins, are provided.
    Type: Application
    Filed: October 7, 2020
    Publication date: April 8, 2021
    Inventor: Peter T. BEERNINK
  • Factor H binding proteins (fHbp) with altered properties and methods of use thereof
    Patent number: 10905754
    Abstract: Factor H binding proteins that can elicit antibodies that are bactericidal for at least one strain of N. meningitidis, and methods of use of such proteins, are provided.
    Type: Grant
    Filed: May 20, 2019
    Date of Patent: February 2, 2021
    Assignee: Children's Hospital & Research Center at Oakland
    Inventors: Peter T. Beernink, Dan M. Granoff
  • Factor H binding protein variants and methods of use thereof
    Patent number: 10836799
    Abstract: Variant factor H binding proteins that can elicit antibodies that are bactericidal for at least one strain of Neisseria meningitidis, compositions comprising such proteins, and methods of use of such proteins, are provided.
    Type: Grant
    Filed: October 11, 2019
    Date of Patent: November 17, 2020
    Assignee: Children's Hospital & Research Center at Oakland
    Inventor: Peter T. Beernink
  • FACTOR H BINDING PROTEIN VARIANTS AND METHODS OF USE THEREOF
    Publication number: 20200109179
    Abstract: Variant factor H binding proteins that can elicit antibodies that are bactericidal for at least one strain of Neisseria meningitidis, compositions comprising such proteins, and methods of use of such proteins, are provided.
    Type: Application
    Filed: October 11, 2019
    Publication date: April 9, 2020
    Inventor: Peter T. BEERNINK
  • FACTOR H BINDING PROTEIN VARIANTS AND METHODS OF USE THEREOF
    Publication number: 20200095288
    Abstract: Variant factor H binding proteins that can elicit antibodies that are bactericidal for at least one strain of Neisseria meningitidis, compositions comprising such proteins, and methods of use of such proteins, are provided.
    Type: Application
    Filed: October 11, 2019
    Publication date: March 26, 2020
    Inventor: Peter T. BEERNINK
  • Factor H Binding Proteins (FHBP) with Altered Properties and Methods of Use Thereof
    Publication number: 20200000907
    Abstract: Factor H binding proteins that can elicit antibodies that are bactericidal for at least one strain of N. meningitidis, and methods of use of such proteins, are provided.
    Type: Application
    Filed: May 20, 2019
    Publication date: January 2, 2020
    Inventors: Peter T. Beernink, Dan M. Granoff
  • Factor H binding protein variants and methods of use thereof
    Patent number: 10487122
    Abstract: Variant factor H binding proteins that can elicit antibodies that are bactericidal for at least one strain of Neisseria meningitidis, compositions comprising such proteins, and methods of use of such proteins, are provided.
    Type: Grant
    Filed: February 28, 2019
    Date of Patent: November 26, 2019
    Assignee: Children's Hospital & Research Center at Oakland
    Inventor: Peter T. Beernink
  • FACTOR H BINDING PROTEIN VARIANTS AND METHODS OF USE THEREOF
    Publication number: 20190225655
    Abstract: Variant factor H binding proteins that can elicit antibodies that are bactericidal for at least one strain of Neisseria meningitidis, compositions comprising such proteins, and methods of use of such proteins, are provided.
    Type: Application
    Filed: February 28, 2019
    Publication date: July 25, 2019
    Inventor: Peter T. Beernink
  • Factor H binding proteins (FHBP) with altered properties and methods of use thereof
    Patent number: 10342860
    Abstract: Factor H binding proteins that can elicit antibodies that are bactericidal for at least one strain of N. meningitidis, and methods of use of such proteins, are provided.
    Type: Grant
    Filed: October 24, 2017
    Date of Patent: July 9, 2019
    Assignee: Children's Hospital & Research Center At Oakland
    Inventors: Peter T. Beernink, Dan M. Granoff
  • Factor H binding protein variants and methods of use thereof
    Patent number: 10266572
    Abstract: Variant factor H binding proteins that can elicit antibodies that are bactericidal for at least one strain of Neisseria meningitidis, compositions comprising such proteins, and methods of use of such proteins, are provided.
    Type: Grant
    Filed: July 22, 2015
    Date of Patent: April 23, 2019
    Assignee: Children's Hospital & Research Center At Oakland
    Inventor: Peter T. Beernink
  • Factor H Binding Proteins (FHBP) with Altered Properties and Methods of Use Thereof
    Publication number: 20180125962
    Abstract: Factor H binding proteins that can elicit antibodies that are bactericidal for at least one strain of N. meningitidis, and methods of use of such proteins, are provided.
    Type: Application
    Filed: October 24, 2017
    Publication date: May 10, 2018
    Inventors: Peter T. Beernink, Dan M. Granoff, Rolando Pajon Feyt
  • Non-naturally occurring factor H binding proteins (fHbp) and methods of use thereof
    Patent number: 9914756
    Abstract: Non-naturally occurring factor H binding proteins derived from variant 3 fHbp that can elicit antibodies that are bactericidal for at least one strain of N. meningitidis, and methods of use of such proteins, are provided. In certain embodiments, a non-naturally occurring factor H binding protein (fHbp) derived from a naturally occurring variant 3 fHbp is disclosed. The non-naturally fHbp may include a substitution of the histidine at position 223 of the naturally occurring variant 3 fHbp with an amino acid selected from the group consisting of arginine, lysine, phenylalanine, tyrosine, or tryptophan, wherein the numbering of position 223 is based on the numbering of the mature fHbp ID 1. The non-naturally occurring fHbp may have a lower affinity for human factor H (fH) than fHbp ID 79.
    Type: Grant
    Filed: August 1, 2014
    Date of Patent: March 13, 2018
    Assignee: CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND
    Inventor: Peter T. Beernink
  • Factor H binding proteins (FHBP) with altered properties and methods of use thereof
    Patent number: 9827300
    Abstract: Factor H binding proteins that can elicit antibodies that are bactericidal for at least one strain of N. meningitidis, and methods of use of such proteins, are provided.
    Type: Grant
    Filed: March 29, 2011
    Date of Patent: November 28, 2017
    Assignee: Children's Hospital & Research Center Oakland
    Inventors: Peter T. Beernink, Dan M. Granoff