Patents by Inventor Peter Toogood
Peter Toogood has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20230221223Abstract: A sample processing assembly for treatment of a sample on a substrate includes a mounting surface for the substrate and a closure body configured to releasably retain a cover member. The closure body is movable between an open position and a substantially closed position. When a substrate is placed in the assembly and the closure body is in the substantially closed position while retaining a cover member, a reaction chamber is formed for processing a sample. A cover member for use with the sample processing assembly is also provided.Type: ApplicationFiled: March 13, 2023Publication date: July 13, 2023Applicant: LEICA BIOSYSTEMS MELBOURNE PTY LTDInventors: Kenneth HENG-CHONG NG, Mark Brian Dockrill, Peter Toogood, Martin Limon, Daniel Dobrogorsky, Mark Wilcock, Greg Boyes, Brendyn Rodgers, Stephen John Bagnato, Ashan Chiranga Perera
-
Patent number: 11635356Abstract: A sample processing assembly for treatment of a sample on a substrate includes a mounting surface for the substrate and a closure body configured to releasably retain a cover member. The closure body is movable between an open position and a substantially closed position. When a substrate is placed in the assembly and the closure body is in the substantially closed position while retaining a cover member, a reaction chamber is formed for processing a sample. A cover member for use with the sample processing assembly is also provided.Type: GrantFiled: June 24, 2020Date of Patent: April 25, 2023Assignee: LEICA BIOSYSTEMS MELBOURNE PTY LTDInventors: Kenneth Heng-Chong Ng, Mark Brian Dockrill, Peter Toogood, Martin Limon, Daniel Dobrogorsky, Mark Wilcock, Greg Boyes, Brendyn Rodgers, Stephen John Bagnato, Ashan Chiranga Perera
-
Publication number: 20230077728Abstract: A cover member for a substrate supporting a biological sample comprises first and second opposing ends, first and second opposing surfaces, a void in the second surface which, when juxtaposed with a substrate, forms a chamber, and a fluid inlet toward the first end and in fluid communication with the void. The void is bounded by void walls having one or more contoured regions for enhancing fluid movement within the chamber. A treatment module for a biological sample comprises the cover member, a support surface for a substrate bearing the biological sample and clamp means operable to releasably retain the cover member in juxtaposition with the substrate for an incubation period. A method for incubating the biological sample with one or more reagents uses the cover member.Type: ApplicationFiled: July 20, 2022Publication date: March 16, 2023Applicant: LEICA BIOSYSTEMS MELBOURNE PTY LTDInventors: Mark Brian DOCKRILL, Anthony FAVALORO, Kenneth HE-CHO NG, Martin LIMON, Peter TOOGOOD, Stephen John BAGNATO
-
Patent number: 11420200Abstract: A cover member for a substrate supporting a biological sample comprises first and second opposing ends, first and second opposing surfaces, a void in the second surface which, when juxtaposed with a substrate, forms a chamber, and a fluid inlet toward the first end and in fluid communication with the void. The void is bounded by void walls having one or more contoured regions for enhancing fluid movement within the chamber. A treatment module for a biological sample comprises the cover member, a support surface for a substrate bearing the biological sample and clamp means operable to releasably retain the cover member in juxtaposition with the substrate for an incubation period. A method for incubating the biological sample with one or more reagents uses the cover member.Type: GrantFiled: January 3, 2020Date of Patent: August 23, 2022Assignee: LEICA BIOSYSTEMS MELBOURNE PTY LTDInventors: Mark Brian Dockrill, Anthony Favaloro, Kenneth Heng-Chong Ng, Martin Limon, Peter Toogood, Stephen John Bagnato
-
Publication number: 20210080359Abstract: A thermal system for controllably altering a temperature within a reaction chamber in a sample processing assembly is described. The reaction chamber is bounded by a substrate and cover member in the sample processing assembly. The thermal system includes at least one thermal generator for generating temperature changes, one or more transfer layers for transferring temperature changes between the thermal generator and the sample on the substrate and a fluid isolator for isolating the thermal generator from fluid dispensed into the reaction chamber.Type: ApplicationFiled: November 10, 2020Publication date: March 18, 2021Applicant: LEICA BIOSYSTEMS MELBOURNE PTY LTDInventors: Peter TOOGOOD, Kenneth HENG-CHONG NG, Anthony FAVALORO, Stephen John BAGNATO, Gregory William BOYES
-
Patent number: 10876936Abstract: A thermal system for controllably altering a temperature within a reaction chamber in a sample processing assembly is described. The reaction chamber is bounded by a substrate and cover member in the sample processing assembly. The thermal system includes at least one thermal generator for generating temperature changes, one or more transfer layers for transferring temperature changes between the thermal generator and the sample on the substrate and a fluid isolator for isolating the thermal generator from fluid dispensed into the reaction chamber.Type: GrantFiled: December 3, 2013Date of Patent: December 29, 2020Assignee: LEICA BIOSYSTEMS MELBOURNE PTY LTDInventors: Peter Toogood, Kenneth Heng-Chong Ng, Anthony Favaloro, Stephen John Bagnato, Gregory William Boyes
-
Patent number: 10718695Abstract: A sample processing assembly for treatment of a sample on a substrate includes a mounting surface for the substrate and a closure body configured to releasably retain a cover member. The closure body is movable between an open position and a substantially closed position. When a substrate is placed in the assembly and the closure body is in the substantially closed position while retaining a cover member, a reaction chamber is formed for processing a sample. A cover member for use with the sample processing assembly is also provided.Type: GrantFiled: October 30, 2018Date of Patent: July 21, 2020Assignee: LEICA BIOSYSTEMS MELBOURNE PTY LTDInventors: Kenneth Heng-Chong Ng, Mark Brian Dockrill, Peter Toogood, Martin Limon, Daniel Dobrogorsky, Mark Wilcock, Greg Boyes, Brendyn Rodgers, Stephen John Bagnato, Ashan Chiranga Perera
-
Publication number: 20200188904Abstract: A cover member for a substrate supporting a biological sample comprises first and second opposing ends, first and second opposing surfaces, a void in the second surface which, when juxtaposed with a substrate, forms a chamber, and a fluid inlet toward the first end and in fluid communication with the void. The void is bounded by void walls having one or more contoured regions for enhancing fluid movement within the chamber. A treatment module for a biological sample comprises the cover member, a support surface for a substrate bearing the biological sample and clamp means operable to releasably retain the cover member in juxtaposition with the substrate for an incubation period. A method for incubating the biological sample with one or more reagents uses the cover member.Type: ApplicationFiled: January 3, 2020Publication date: June 18, 2020Applicant: LEICA BIOSYSTEMS MELBOURNE PTY LTDInventors: Mark Brian Dockrill, Anthony Favaloro, Kenneth Heng-Chong Ng, Martin Limon, Peter Toogood, Stephen John Bagnato
-
Patent number: 10549271Abstract: A cover member for a substrate supporting a biological sample comprises first and second opposing ends, first and second opposing surfaces, a void in the second surface which, when juxtaposed with a substrate, forms a chamber, and a fluid inlet toward the first end and in fluid communication with the void. The void is bounded by void walls having one or more contoured regions for enhancing fluid movement within the chamber. A treatment module for a biological sample comprises the cover member, a support surface for a substrate bearing the biological sample and clamp means operable to releasably retain the cover member in juxtaposition with the substrate for an incubation period. A method for incubating the biological sample with one or more reagents uses the cover member.Type: GrantFiled: November 15, 2012Date of Patent: February 4, 2020Assignee: LEICA BIOSYSTEMS MELBOURNE PTY LIMITEDInventors: Mark Brian Dockrill, Anthony Favaloro, Kenneth Heng-Chong Ng, Martin Limon, Peter Toogood, Stephen John Bagnato
-
Publication number: 20190078986Abstract: A sample processing assembly for treatment of a sample on a substrate includes a mounting surface for the substrate and a closure body configured to releasably retain a cover member. The closure body is movable between an open position and a substantially closed position. When a substrate is placed in the assembly and the closure body is in the substantially closed position while retaining a cover member, a reaction chamber is formed for processing a sample. A cover member for use with the sample processing assembly is also provided.Type: ApplicationFiled: October 30, 2018Publication date: March 14, 2019Applicant: LEICA BIOSYSTEMS MELBOURNE PTY LTDInventors: Kenneth Heng-Chong NG, Mark Brian DOCKRILL, Peter TOOGOOD, Martin LIMON, Daniel DOBROGORSKY, Mark WILCOCK, Greg BOYES, Brendyn RODGERS, Stephen John BAGNATO, Ashan Chiranga PERERA
-
Patent number: 10145767Abstract: A sample processing assembly for treatment of a sample on a substrate includes a mounting surface for the substrate and a closure body configured to releasably retain a cover member. The closure body is movable between an open position and a substantially closed position. When a substrate is placed in the assembly and the closure body is in the substantially closed position while retaining a cover member, a reaction chamber is formed for processing a sample. A cover member for use with the sample processing assembly is also provided.Type: GrantFiled: November 1, 2013Date of Patent: December 4, 2018Assignee: LEICA BIOSYSTEMS MELBOURNE PTY LTDInventors: Kenneth Heng-chong Ng, Mark Brian Dockrill, Peter Toogood, Martin Limon, Daniel Dobrogorsky, Mark Wilcock, Greg Boyes, Brendyn Rodgers, Stephen John Bagnato, Ashan Chiranga Perera
-
Publication number: 20150308931Abstract: A thermal system for controllably altering a temperature within a reaction chamber in a sample processing assembly is described. The reaction chamber is bounded by a substrate and cover member in the sample processing assembly. The thermal system includes at least one thermal generator for generating temperature changes, one or more transfer layers for transferring temperature changes between the thermal generator and the sample on the substrate and a fluid isolator for isolating the thermal generator from fluid dispensed into the reaction chamber.Type: ApplicationFiled: December 3, 2013Publication date: October 29, 2015Applicant: LEICA BIOSYSTEMS MELBOURNE PTY LTDInventors: Peter TOOGOOD, Kenneth Heng-Chong NG, Anthony FAVALORO, Stephen John BAGNATO, Gregory William BOYES
-
Publication number: 20150253225Abstract: A sample processing assembly for treatment of a sample on a substrate includes a mounting surface for the substrate and a closure body configured to releasably retain a cover member. The closure body is movable between an open position and a substantially closed position. When a substrate is placed in the assembly and the closure body is in the substantially closed position while retaining a cover member, a reaction chamber is formed for processing a sample. A cover member for use with the sample processing assembly is also provided.Type: ApplicationFiled: November 1, 2013Publication date: September 10, 2015Applicant: LEICA BIOSYSTEMS MELBOURNE PTY LTDInventors: Kenneth Heng-chong Ng, Mark Brian Dockrill, Peter Toogood, Martin Limon, Daniel Dobrogorsky, Mark Wilcock, Greg Boyes, Brendyn Rodgers, Stephen John Bagnato, Ashan Chiranga Perera
-
Publication number: 20140315256Abstract: A cover member for a substrate supporting a biological sample comprises first and second opposing ends, first and second opposing surfaces, a void in the second surface which, when juxtaposed with a substrate, forms a chamber, and a fluid inlet toward the first end and in fluid communication with the void. The void is bounded by void walls having one or more contoured regions for enhancing fluid movement within the chamber. A treatment module for a biological sample comprises the cover member, a support surface for a substrate bearing the biological sample and clamp means operable to releasably retain the cover member in juxtaposition with the substrate for an incubation period. A method for incubating the biological sample with one or more reagents uses the cover member.Type: ApplicationFiled: November 15, 2012Publication date: October 23, 2014Applicant: LEICA BIOSYSTEMS MELBOURNE PTY LTDInventors: Mark Brian Dockrill, Anthony Favaloro, Kenneth Heng-Chong Ng, Martin Limon, Peter Toogood, Stephen John Bagnato
-
Patent number: 8497307Abstract: The invention provides to a family of aryl guanidine—based F1F0—ATPase inhibitors, e.g., mitochondrial F1F0—ATPase inhibitors, methods for their discovery, and their use as therapeutic agents for treating certain disorders.Type: GrantFiled: September 11, 2009Date of Patent: July 30, 2013Assignee: The Regents of the University of MichiganInventors: Gary D. Glick, Peter Toogood, Gina Ney
-
Publication number: 20110251200Abstract: The invention provides to a family of aryl guanidine-based F1F0-ATPase inhibitors, e.g., mitochondrial F1F0-ATPase inhibitors, methods for their discovery, and their use as therapeutic agents for treating certain disorders.Type: ApplicationFiled: September 11, 2009Publication date: October 13, 2011Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGANInventors: Gary D. Glick, Peter Toogood, Gina Ney
-
Patent number: 7501425Abstract: This invention provides substituted pyrimido-pyrimidines that are useful for treating cell proliferative disorders, such as cancer and restenosis, as well as angiogenesis and atherosclerosis. The invention compounds have Formula I: where W is NH, S, SO, or SO2, R1 includes alkyl, cycloalkyl, phenyl, substituted phenyl, heteroaryl and substituted heteroaryl; R2 includes alkyl, cycloalkyl, phenyl and substituted phenyl; R3 includes alkyl and aryl such as phenyl and substituted phenyl; R8 and R9 include hydrogen and alkyl, and the pharmaceutically acceptable salts thereof. The invention also provides pharmaceutical formulations comprising a compound of Formula I together with a pharmaceutically acceptable carrier, diluent, or excipient therefor, and a method for treating angiogenesis using said compounds.Type: GrantFiled: May 10, 1999Date of Patent: March 10, 2009Assignee: Warner Lambert CompanyInventors: Ellen Myra Dobrusin, James Marino Hamby, James Bernard Kramer, Mel Conrad Schroeder, Howard Daniel Hollis Showalter, Peter Toogood, Susanne A. Trumpp-Kallmeyer
-
Publication number: 20080021037Abstract: Disclosed are polymorphs of the isethionate salt of 6-acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one, which is a selective cyclin-dependent kinase 4 (CDK4) inhibitor useful for treating inflammation and cell proliferative diseases such as cancer and restenosis.Type: ApplicationFiled: September 26, 2007Publication date: January 24, 2008Inventors: Vladimar Beylin, Anthony Blackburn, David Erdman, Peter Toogood
-
Publication number: 20070197518Abstract: Described herein are antibacterial compounds, methods for making the compounds, pharmaceutical compositions containing the compounds and methods of treating bacterial infections utilizing the compounds and pharmaceutical composition.Type: ApplicationFiled: December 19, 2006Publication date: August 23, 2007Inventors: Timothy Johnson, Dennis McNamara, Debra Sherry, Peter Toogood
-
Publication number: 20070179118Abstract: The present invention provides substituted 2-aminopyridines useful in treating cell proliferative disorders. The novel compounds of the present invention are potent inhibitors of cyclin-dependent kinases 4 (cdk4).Type: ApplicationFiled: April 11, 2007Publication date: August 2, 2007Inventors: Mark Barvian, Richard Booth, John Quin, Joseph Repine, Derek Sheehan, Peter Toogood, Scott Vanderwel, Hairong Zhou