Patents by Inventor Peter Tseng
Peter Tseng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230314181Abstract: Systems and methods for passive and/or active wireless sensor networks with augmented telemetry using coupled magnetic resonances in accordance with embodiments of the invention are disclosed. In one embodiment, a wireless sensor network is provided, the wireless sensor network comprising a transmitter configured to couple with a reader, a receiver configured to couple with a sensor, wherein the sensor is configured to detect at least one parameter and generate sensor data, wherein the sensor data maps onto the receiver, and wherein the transmitter and the receiver are inductively coupled creating a link between the reader and the sensor.Type: ApplicationFiled: August 20, 2021Publication date: October 5, 2023Inventors: Peter Tseng, Amirhossein Hajiaghajani
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Patent number: 11592438Abstract: A system for assaying forces applied by cells includes an optically transparent substrate comprising a soft material having a Young's modulus within the range of about 3 kPa to about 100 kPa. An array of molecular patterns is disposed on a surface of the optically transparent substrate, the molecular patterns include fluorophore-conjugated patterns adherent to cells. The system includes at least one light source configured to excite the fluorophore-conjugated patterns and an imaging device configured to capture fluorescent light emitted from the fluorophore-conjugated patterns. Dimensional changes in the size of the patterns are used to determine contractile forces imparted by cells located on the patterns.Type: GrantFiled: October 7, 2021Date of Patent: February 28, 2023Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Dino Di Carlo, Peter Tseng, Ivan Pushkarsky
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Publication number: 20220384081Abstract: Embodiments herein are directed to a system and a method of selectively manipulating magnetically-barcoded materials from background magnetic materials. Magnetic barcodes include layers of magnetic anisotropy. These are then manipulated by a magnetic system that can drive spatio-temporal magnetic fields that can “match” a barcode to drive a specific interaction, thereby providing a “lock-key” interaction. This technique is able to selectively manipulate magnetically-barcoded materials, and can have applications across a variety of magnetic systems such as cell separation, drug delivery, valves, and motors.Type: ApplicationFiled: September 29, 2020Publication date: December 1, 2022Applicant: The Regents of the University of CaliforniaInventors: Peter TSENG, Amirhossein HAJIAGHAJANI
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Publication number: 20220255356Abstract: A sensor device includes an inner hydrogel layer, a first planar metallic structure adjacent to a first surface of the inner hydrogel layer, and a second planar metallic structure adjacent to a second surface of the inner hydrogel layer opposite to the first surface. A sensor device further includes an encasing layer at least partially enclosing at least one of the inner hydrogel layer, the first planar metallic structure, and the second planar metallic structure. A method for use of the sensor device includes receiving at least one environmental stimulus, modifying a capacitance of a hydrogel in response to the received environmental stimulus, and generating an electrical stimulus response based on the modified capacitance. The method further includes modifying the capacitance of the hydrogel by modifying a resonant frequency of the hydrogel.Type: ApplicationFiled: July 22, 2020Publication date: August 11, 2022Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Peter Tseng, Manik Dautta, Muhannad Alshetaiwi
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Patent number: 11248313Abstract: This present disclosure provides methods for utilizing such forces in when generating nanofibrillar constructs with engineered morphology from the nano- to macro-scales. Using for example, a biopolymer silk fibroin as a base material, patterns an intermediate hydrogel were generated within a deformable mold. Subsequently, mechanical tension was introduced via either hydrogel contraction or mold deformation, and finally a material is reentrapped in this transformed shape via beta-sheet crystallization and critical point drying. Topdown engineered anchorages, cables, and shapes act in concert to mediate precision changes in nanofiber alignment/orientation and a macroscale form of provided nanofibrillar structure. An ability of this technique to engineer large gradients of nano- and micro-scale order, manipulate mechanical properties (such as plasticity and thermal transport), and the in-situ generation of 2D and 3D, multi-tiered and doped, nanofibrillar constructs was demonstrated.Type: GrantFiled: August 1, 2017Date of Patent: February 15, 2022Assignee: Trustees of Tufts CollegeInventors: Fiorenzo G. Omenetto, Peter Tseng
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Publication number: 20220026412Abstract: A system for assaying forces applied by cells includes an optically transparent substrate comprising a soft material having a Young's modulus within the range of about 3 kPa to about 100 kPa. An array of molecular patterns is disposed on a surface of the optically transparent substrate, the molecular patterns include fluorophore-conjugated patterns adherent to cells. The system includes at least one light source configured to excite the fluorophore-conjugated patterns and an imaging device configured to capture fluorescent light emitted from the fluorophore-conjugated patterns. Dimensional changes in the size of the patterns are used to determine contractile forces imparted by cells located on the patterns.Type: ApplicationFiled: October 7, 2021Publication date: January 27, 2022Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Dino Di Carlo, Peter Tseng, Ivan Pushkarsky
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Publication number: 20220013212Abstract: A system for tracking diet and nutrition includes an oral module configured to be affixed within a mouth of a user and including a set of salivary sensors responsive to a level of at least one nutrient. The system also includes a set of eating event sensors responsive to an eating event. The set of eating event sensors can be included in the oral module, or can be included in a body module configured to be affixed adjacent to a body part of the user.Type: ApplicationFiled: November 15, 2019Publication date: January 13, 2022Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Peter TSENG, Mohammad AL FARUQUE, Fadi KURDAHI
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Patent number: 11175280Abstract: A system for assaying forces applied by cells includes an optically transparent substrate comprising a soft material having a Young's modulus within the range of about 3 kPa to about 100 kPa. An array of molecular patterns is disposed on a surface of the optically transparent substrate, the molecular patterns include fluorophore-conjugated patterns adherent to cells. The system includes at least one light source configured to excite the fluorophore-conjugated patterns and an imaging device configured to capture fluorescent light emitted from the fluorophore-conjugated patterns. Dimensional changes in the size of the patterns are used to determine contractile forces imparted by cells located on the patterns.Type: GrantFiled: September 25, 2020Date of Patent: November 16, 2021Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Dino Di Carlo, Peter Tseng, Ivan Pushkarsky
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Patent number: 11026603Abstract: This disclosure provides a dielectric sensor configured to detect a physiological variable within a subject. The dielectric sensor having at least one split-ring resonator configured to be positioned within an oral cavity of the subject and to be bioresponsive to at least one physiological variable. The split-ring resonator having a first resonator loop, a second resonator loop, and a dielectric interlayer interposed between and contacting the first resonator and the second resonator.Type: GrantFiled: April 3, 2019Date of Patent: June 8, 2021Assignee: Trustees of Tufts CollegeInventors: Fiorenzo G. Omenetto, Peter Tseng, Bradley Napier, Mark Brenckle, Logan Garbarini
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Publication number: 20210018491Abstract: A system for assaying forces applied by cells includes an optically transparent substrate comprising a soft material having a Young's modulus within the range of about 3 kPa to about 100 kPa. An array of molecular patterns is disposed on a surface of the optically transparent substrate, the molecular patterns include fluorophore-conjugated patterns adherent to cells. The system includes at least one light source configured to excite the fluorophore-conjugated patterns and an imaging device configured to capture fluorescent light emitted from the fluorophore-conjugated patterns. Dimensional changes in the size of the patterns are used to determine contractile forces imparted by cells located on the patterns.Type: ApplicationFiled: September 25, 2020Publication date: January 21, 2021Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Dino Di Carlo, Peter Tseng, Ivan Pushkarsky
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Patent number: 10816540Abstract: A system for assaying forces applied by cells includes an optically transparent substrate comprising a soft material having a Young's modulus within the range of about 3 kPa to about 100 kPa. An array of molecular patterns is disposed on a surface of the optically transparent substrate, the molecular patterns include fluorophore-conjugated patterns adherent to cells. The system includes at least one light source configured to excite the fluorophore-conjugated patterns and an imaging device configured to capture fluorescent light emitted from the fluorophore-conjugated patterns. Dimensional changes in the size of the patterns are used to determine contractile forces imparted by cells located on the patterns.Type: GrantFiled: September 26, 2019Date of Patent: October 27, 2020Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Dino Di Carlo, Peter Tseng, Ivan Pushkarsky
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Publication number: 20200025745Abstract: A system for assaying forces applied by cells includes an optically transparent substrate comprising a soft material having a Young's modulus within the range of about 3 kPa to about 100 kPa. An array of molecular patterns is disposed on a surface of the optically transparent substrate, the molecular patterns include fluorophore-conjugated patterns adherent to cells. The system includes at least one light source configured to excite the fluorophore-conjugated patterns and an imaging device configured to capture fluorescent light emitted from the fluorophore-conjugated patterns. Dimensional changes in the size of the patterns are used to determine contractile forces imparted by cells located on the patterns.Type: ApplicationFiled: September 26, 2019Publication date: January 23, 2020Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Dino Di Carlo, Peter Tseng, Ivan Pushkarsky
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Patent number: 10473644Abstract: A system for assaying forces applied by cells includes an optically transparent substrate comprising a soft material having a Young's modulus within the range of about 3 kPa to about 100 kPa. An array of molecular patterns is disposed on a surface of the optically transparent substrate, the molecular patterns include fluorophore-conjugated patterns adherent to cells. The system includes at least one light source configured to excite the fluorophore-conjugated patterns and an imaging device configured to capture fluorescent light emitted from the fluorophore-conjugated patterns. Dimensional changes in the size of the patterns are used to determine contractile forces imparted by cells located on the patterns.Type: GrantFiled: August 20, 2018Date of Patent: November 12, 2019Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Dino Di Carlo, Peter Tseng, Ivan Pushkarsky
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Publication number: 20190292688Abstract: This present disclosure provides methods for utilizing such forces in when generating nanofibrillar constructs with engineered morphology from the nano- to macro-scales. Using for example, a biopolymer silk fibroin as a base material, patterns an intermediate hydrogel were generated within a deformable mold. Subsequently, mechanical tension was introduced via either hydrogel contraction or mold deformation, and finally a material is reentrapped in this transformed shape via beta-sheet crystallization and critical point drying. Topdown engineered anchorages, cables, and shapes act in concert to mediate precision changes in nanofiber alignment/orientation and a macroscale form of provided nanofibrillar structure. An ability of this technique to engineer large gradients of nano- and micro-scale order, manipulate mechanical properties (such as plasticity and thermal transport), and the in-situ generation of 2D and 3D, multi-tiered and doped, nanofibrillar constructs was demonstrated.Type: ApplicationFiled: August 1, 2017Publication date: September 26, 2019Applicant: Trustees of Tufts CollegeInventors: Fiorenzo G. OMENETTO, Peter TSENG
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Publication number: 20190105488Abstract: The present disclosure relates to programmable hydrogel ionic circuits having properties that are advantageous for use in biological systems. In particular, provided herein are programmable hydrogel ionic circuit that exhibit transparency, stretchability, aqueous-based connective interfaces, high-resolution routing of ionic currents between engineered and biological systems, and reduced tissue damage from electrochemical reactions. As described herein, the programmable hydrogel ionic circuits are produced using a combination of microfluidics and aqueous two-phase systems.Type: ApplicationFiled: October 6, 2018Publication date: April 11, 2019Inventors: Siwei Zhao, Peter Tseng, Jonathan Grasman, Yu Wang, Fiorenzo G. Omenetto, David L. Kaplan
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Publication number: 20180356396Abstract: A system for assaying forces applied by cells includes an optically transparent substrate comprising a soft material having a Young's modulus within the range of about 3 kPa to about 100 kPa. An array of molecular patterns is disposed on a surface of the optically transparent substrate, the molecular patterns include fluorophore-conjugated patterns adherent to cells. The system includes at least one light source configured to excite the fluorophore-conjugated patterns and an imaging device configured to capture fluorescent light emitted from the fluorophore-conjugated patterns. Dimensional changes in the size of the patterns are used to determine contractile forces imparted by cells located on the patterns.Type: ApplicationFiled: August 20, 2018Publication date: December 13, 2018Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Dino Di Carlo, Peter Tseng, Ivan Pushkarsky
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Patent number: 10144911Abstract: A system is provided for the quantitative magnetic separation of magnetic objects (e.g., particles or cells). The system uses magnetic ratcheting over arrays of ferromagnetic elements having gradient spacing manifested in various pitch zones that are encountered by the magnetic objects as they traverse the array. The system can be used to separate and concentrate magnetic objects based on iron oxide content. For cells, different phenotypes may be separated based, for example, on surface expression of proteins or molecules that are bound to magnetic particles. The system includes a substrate or chip having the array of ferromagnetic elements with increasing lateral pitch and an externally driven magnet device that generates a cycling magnetic field. Magnetic objects with higher IOC separate and equilibrate along the array at larger pitches. The system can be used for the differential sorting of particles and cells of interest.Type: GrantFiled: December 15, 2015Date of Patent: December 4, 2018Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Dino Di Carlo, Coleman Murray, Edward Pao, Peter Tseng
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Publication number: 20180333295Abstract: An IV pole mountable, therapeutic infusate processing device is incorporated into a hypothermia system to receive therapeutic fluid(s), such as normal saline, peritioneal dialysis solution, or other crystalloid solution, to heat such therapeutic fluid(s) a few degrees centigrade above normal body temperature and to direct the resulting heated infusate to and through a selected anatomical portion of a patients body to raise the temperature of that body portion so as to affect any cancerous or other tumors that may be located therein. The processing device is provided with touch screen controls and visual indicators to facilitate its proper use; while the system further includes temperature and pressure sensors to monitor the hyperthermia processing to insure patient safety.Type: ApplicationFiled: June 15, 2018Publication date: November 22, 2018Inventors: John Landy, Michael Gildersleeve, Yeu Wen Peter Tseng
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Patent number: 10082497Abstract: A system for assaying forces applied by cells includes an optically transparent substrate comprising a soft material having a Young's modulus within the range of about 3 kPa to about 100 kPa. An array of molecular patterns is disposed on a surface of the optically transparent substrate, the molecular patterns include fluorophore-conjugated patterns adherent to cells. The system includes at least one light source configured to excite the fluorophore-conjugated patterns and an imaging device configured to capture fluorescent light emitted from the fluorophore-conjugated patterns. Dimensional changes in the size of the patterns are used to determine contractile forces imparted by cells located on the patterns.Type: GrantFiled: March 27, 2015Date of Patent: September 25, 2018Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Dino Di Carlo, Peter Tseng, Ivan Pushkarsky
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Publication number: 20180147370Abstract: Presented herein are various systems, methods, and apparatuses for heating infusate by an induction heater e.g., an electromagnetic heater, and storing thermal energy in a reservoir of thusly heated infusate. In certain embodiments, a system includes a reservoir for containing an infusate, a fluid heater, a diversion valve, a patient line, and a recirculation line.Type: ApplicationFiled: November 30, 2016Publication date: May 31, 2018Inventors: John J. Landy, III, Yeu Wen Peter Tseng